Perlmutter JS - Search Results

1

Cholinergic dysfunction in occupational manganese exposure.

Hutson TN, Nielsen SS, Senini N, O'Donnell J, Flores HP, Hershey T, Perlmutter JS, Soda AK, Moerlein SM, Tu Z, Kasper M, Sheppard L, Racette BA, Criswell SR. Hutson TN, et al. Among authors: perlmutter js. Neurotoxicology. 2025 Dec;111:103313. doi: 10.1016/j.neuro.2025.103313. Epub 2025 Sep 3. Neurotoxicology. 2025. PMID: 40912474 Free PMC article.

2

Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain.

Qiu L, Jiang H, Zhou C, Wang J, Yu Y, Zhao H, Huang T, Gropler R, Perlmutter JS, Benzinger TLS, Tu Z. Qiu L, et al. Among authors: perlmutter js. J Med Chem. 2023 Apr 13;66(7):4671-4688. doi: 10.1021/acs.jmedchem.2c01752. Epub 2023 Mar 16. J Med Chem. 2023. PMID: 36926861 Free PMC article.

3

PET Quantification of [¹⁸F]VAT in Human Brain and Its Test-Retest Reproducibility and Age Dependence.

O'Donnell JL, Soda AK, Jiang H, Norris SA, Maiti B, Karimi M, Campbell MC, Moerlein SM, Tu Z, Perlmutter JS. O'Donnell JL, et al. Among authors: perlmutter js. J Nucl Med. 2024 Jun 3;65(6):956-961. doi: 10.2967/jnumed.123.266860. J Nucl Med. 2024. PMID: 38604762 Free PMC article.

4

Radiation dosimetry of [¹¹C]TZ1964B as determined by whole-body PET imaging of nonhuman primates.

Maiti B, Goldman NL, Hamdi M, Lenox-Krug J, Karimi M, Moerlein SM, Laforest R, Huang T, Tu Z, Perlmutter JS, Norris SA. Maiti B, et al. Among authors: perlmutter js. EJNMMI Res. 2025 May 14;15(1):57. doi: 10.1186/s13550-025-01221-x. EJNMMI Res. 2025. PMID: 40369374 Free PMC article.

5

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain.

Lang J, Zhou W, Huang T, Jiang H, Chen H, Xu S, Qiu L, Heady M, Yu Y, Brier MR, Nai YH, Guglielmetti C, Perlmutter JS, Tu Z. Lang J, et al. Among authors: perlmutter js. J Med Chem. 2025 Jun 26;68(12):12991-13018. doi: 10.1021/acs.jmedchem.5c00881. Epub 2025 Jun 6. J Med Chem. 2025. PMID: 40476381

6

Two F-18 radiochemistry methods to synthesize a promising transient receptor potential canonical 5 (TRPC5) radioligand.

Yu Y, Jadhav SB, Xing Z, Jiang H, Qiu L, Huang T, Perlmutter JS, Li Z, Tu Z. Yu Y, et al. Among authors: perlmutter js. J Fluor Chem. 2024 Nov;280:110367. doi: 10.1016/j.jfluchem.2024.110367. Epub 2024 Oct 22. J Fluor Chem. 2024. PMID: 40520526 Free PMC article.

7

Radiation dosimetry and fasting-dependent hepatobiliary clearance of the VAChT-specific PET radioligand ¹⁸F-VAT in humans.

Norris SA, Goldman NL, Hamdi M, Moerlein SM, Laforest R, Karimi M, Perlmutter JS, Tu Z. Norris SA, et al. Among authors: perlmutter js. EJNMMI Res. 2025 Jul 7;15(1):83. doi: 10.1186/s13550-025-01273-z. EJNMMI Res. 2025. PMID: 40622650 Free PMC article.

8

Evaluation of [¹¹C]CS1P1 in Healthy Young and Older Adults.

Friedrichsen KA, Judge BA, Jones LA, Rajamanickam J, Qiu L, Soda AK, Rahmani F, Benzinger GR, King CR, Chaney AM, Nickels ML, Gropler RJ, Raji CA, White RL, Perlmutter JS, Laforest R, An H, Tu Z, Benzinger TLS, Brier MR. Friedrichsen KA, et al. Among authors: perlmutter js. AJNR Am J Neuroradiol. 2026 Jan 5;47(1):175-183. doi: 10.3174/ajnr.A8944. AJNR Am J Neuroradiol. 2026. PMID: 40721280 Free PMC article.

9

Automated production of radiotracer [¹⁸F]FZTA for imaging sphingosine-1-phosphate receptor 1 (S1PR1) in human.

Qiu L, Bognar C, Tangadanchu VKR, Moerlein SM, Gaehle GG, Gropler RJ, Perlmutter JS, Benzinger TLS, Tu Z. Qiu L, et al. Among authors: perlmutter js. Appl Radiat Isot. 2025 Dec;226:112136. doi: 10.1016/j.apradiso.2025.112136. Epub 2025 Aug 25. Appl Radiat Isot. 2025. PMID: 40884909

10

Discovery and in vivo evaluation of a fluorine-18 pro-drug tracer for imaging sphingosine-1-phosphate receptor 2 in the brain.

Qiu L, Zhou W, Chen H, Jiang H, Lang J, Xing Z, Heady M, Gropler RJ, Guglielmetti C, Perlmutter JS, Tu Z. Qiu L, et al. Among authors: perlmutter js. Bioorg Med Chem. 2026 Mar;134:118536. doi: 10.1016/j.bmc.2025.118536. Epub 2025 Dec 20. Bioorg Med Chem. 2026. PMID: 41448024

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