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Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis.
Weldy CS, Li Q, Monteiro JP, Peters TS, Guo H, Galls D, Gu W, Cheng PP, Ramste M, Li D, Palmisano BT, Sharma D, Worssam MD, Zhao Q, Bhate A, Kundu RK, Nguyen T, Mokry M, Miller CL, van der Laan SW, Li JB, Quertermous T. Weldy CS, et al. Among authors: nguyen t. Nat Cardiovasc Res. 2025 Oct;4(10):1241-1257. doi: 10.1038/s44161-025-00710-5. Epub 2025 Sep 16. Nat Cardiovasc Res. 2025. PMID: 40958051 Free PMC article.
Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.
Miller CL, Pjanic M, Wang T, Nguyen T, Cohain A, Lee JD, Perisic L, Hedin U, Kundu RK, Majmudar D, Kim JB, Wang O, Betsholtz C, Ruusalepp A, Franzén O, Assimes TL, Montgomery SB, Schadt EE, Björkegren JLM, Quertermous T. Miller CL, et al. Among authors: nguyen t. Nat Commun. 2016 Jul 8;7:12092. doi: 10.1038/ncomms12092. Nat Commun. 2016. PMID: 27386823 Free PMC article.
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.
Kim JB, Pjanic M, Nguyen T, Miller CL, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic LP, Maegdefessel L, Hedin U, Quertermous T. Kim JB, et al. Among authors: nguyen t. PLoS Genet. 2017 May 8;13(5):e1006750. doi: 10.1371/journal.pgen.1006750. eCollection 2017 May. PLoS Genet. 2017. PMID: 28481916 Free PMC article.
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Nanda V, Wang T, Pjanic M, Liu B, Nguyen T, Matic LP, Hedin U, Koplev S, Ma L, Franzén O, Ruusalepp A, Schadt EE, Björkegren JLM, Montgomery SB, Snyder MP, Quertermous T, Leeper NJ, Miller CL. Nanda V, et al. Among authors: nguyen t. PLoS Genet. 2018 Nov 16;14(11):e1007755. doi: 10.1371/journal.pgen.1007755. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30444878 Free PMC article.
Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Wirka RC, et al. Among authors: nguyen t. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. Nat Med. 2019. PMID: 31359001 Free PMC article.
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