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Page 1
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis.
Liu X, He A, Lu D, Hu D, Tan M, Abere A, Goodarzi P, Ahmad B, Kleiboeker B, Finck BN, Zayed M, Funai K, Brestoff JR, Javaheri A, Weisensee P, Mittendorfer B, Hsu FF, Van Veldhoven PP, Razani B, Semenkovich CF, Lodhi IJ. Liu X, et al. Among authors: javaheri a. Nature. 2025 Oct;646(8087):1223-1231. doi: 10.1038/s41586-025-09517-7. Epub 2025 Sep 17. Nature. 2025. PMID: 40963015 Free PMC article.
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Zhang X, Kapoor D, Jeong SJ, Fappi A, Stitham J, Shabrish V, Sergin I, Yousif E, Rodriguez-Velez A, Yeh YS, Park A, Yurdagul A Jr, Rom O, Epelman S, Schilling JD, Sardiello M, Diwan A, Cho J, Stitziel NO, Javaheri A, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: javaheri a. Nat Metab. 2024 Feb;6(2):359-377. doi: 10.1038/s42255-024-00984-2. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409323 Free PMC article.
Ketones with a twist: Tipping the heart's hat to fat.
Javaheri A, Mittendorfer B. Javaheri A, et al. Obesity (Silver Spring). 2024 Mar;32(3):452-453. doi: 10.1002/oby.23990. Epub 2024 Jan 29. Obesity (Silver Spring). 2024. PMID: 38287645 Free PMC article. No abstract available.
Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis.
Yeh YS, Evans TD, Iwase M, Jeong SJ, Zhang X, Liu Z, Park A, Ghasemian A, Dianati B, Javaheri A, Kratky D, Kawarasaki S, Goto T, Zhang H, Dutta P, Schopfer FJ, Straub AC, Cho J, Lodhi IJ, Razani B. Yeh YS, et al. Among authors: javaheri a. J Clin Invest. 2025 Mar 17;135(6):e185340. doi: 10.1172/JCI185340. J Clin Invest. 2025. PMID: 40091840 Free PMC article.
Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Ozcan M, Guo Z, Valenzuela Ripoll C, Diab A, Picataggi A, Rawnsley D, Lotfinaghsh A, Bergom C, Szymanski J, Hwang D, Asnani A, Kosiborod M, Zheng J, Hayashi RJ, Woodard PK, Kovacs A, Margulies KB, Schilling J, Razani B, Diwan A, Javaheri A. Ozcan M, et al. Among authors: javaheri a. Cell Metab. 2023 Jun 6;35(6):928-942.e4. doi: 10.1016/j.cmet.2023.02.006. Epub 2023 Mar 2. Cell Metab. 2023. PMID: 36868222 Free PMC article. Clinical Trial.
Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling.
Islam M, Rawnsley DR, Ma X, Navid W, Zhao C, Guan X, Foroughi L, Murphy JT, Navid H, Weinheimer CJ, Kovacs A, Nigro J, Diwan A, Chang RP, Kumari M, Young ME, Razani B, Margulies KB, Abdellatif M, Sedej S, Javaheri A, Covey DF, Mani K, Diwan A. Islam M, et al. Among authors: javaheri a. J Clin Invest. 2025 Feb 11;135(7):e163730. doi: 10.1172/JCI163730. J Clin Invest. 2025. PMID: 39932799 Free PMC article.
157 results