Spring DR - Search Results

1

β-Lactamase cleavable antimicrobial peptide-drug conjugates.

Deingruber T, Gaynord JS, Gan BH, Kostadinova KA, O'Brien TJ, Tan YS, Parker JS, Hunt TA, Carroll JS, Welch M, Spring DR. Deingruber T, et al. Among authors: spring dr. Chem Sci. 2025 Sep 19. doi: 10.1039/d5sc06369h. Online ahead of print. Chem Sci. 2025. PMID: 40979881 Free PMC article.

2

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Among authors: spring dr. Chem Sci. 2018 Nov 9;10(3):694-700. doi: 10.1039/c8sc04645j. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774870 Free PMC article.

3

Cleavable linkers in antibody-drug conjugates.

Bargh JD , Isidro-Llobet A , Parker JS , Spring DR . Bargh JD , et al. Among authors: spring dr. Chem Soc Rev. 2019 Aug 12;48(16):4361-4374. doi: 10.1039/c8cs00676h. Chem Soc Rev. 2019. PMID: 31294429 Review.

4

The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions.

Gan BH, Gaynord J, Rowe SM, Deingruber T, Spring DR. Gan BH, et al. Among authors: spring dr. Chem Soc Rev. 2021 Jul 5;50(13):7820-7880. doi: 10.1039/d0cs00729c. Chem Soc Rev. 2021. PMID: 34042120 Free PMC article. Review.

5

Sulfatase-cleavable linkers for antibody-drug conjugates.

Bargh JD, Walsh SJ, Isidro-Llobet A, Omarjee S, Carroll JS, Spring DR. Bargh JD, et al. Among authors: spring dr. Chem Sci. 2020 Jan 27;11(9):2375-2380. doi: 10.1039/c9sc06410a. Chem Sci. 2020. PMID: 34084399 Free PMC article.

6

Rapid and robust cysteine bioconjugation with vinylheteroarenes.

Seki H, Walsh SJ, Bargh JD, Parker JS, Carroll J, Spring DR. Seki H, et al. Among authors: spring dr. Chem Sci. 2021 Jun 7;12(26):9060-9068. doi: 10.1039/d1sc02722k. eCollection 2021 Jul 7. Chem Sci. 2021. PMID: 34276935 Free PMC article.

7

Stapled peptides as a new technology to investigate protein-protein interactions in human platelets.

Iegre J, Ahmed NS, Gaynord JS, Wu Y, Herlihy KM, Tan YS, Lopes-Pires ME, Jha R, Lau YH, Sore HF, Verma C, O' Donovan DH, Pugh N, Spring DR. Iegre J, et al. Among authors: spring dr. Chem Sci. 2018 Apr 25;9(20):4638-4643. doi: 10.1039/c8sc00284c. eCollection 2018 May 28. Chem Sci. 2018. PMID: 29899957 Free PMC article.

8

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Among authors: spring dr. Chem Sci. 2018 Dec 13;10(2):633-634. doi: 10.1039/c8sc90248h. eCollection 2019 Jan 14. Chem Sci. 2018. PMID: 30778404 Free PMC article.

9

Site-selective modification strategies in antibody-drug conjugates.

Walsh SJ , Bargh JD , Dannheim FM , Hanby AR , Seki H , Counsell AJ , Ou X , Fowler E , Ashman N , Takada Y , Isidro-Llobet A , Parker JS , Carroll JS , Spring DR . Walsh SJ , et al. Among authors: spring dr. Chem Soc Rev. 2021 Jan 21;50(2):1305-1353. doi: 10.1039/d0cs00310g. Epub 2020 Dec 8. Chem Soc Rev. 2021. PMID: 33290462 Review.

10

A dual-enzyme cleavable linker for antibody-drug conjugates.

Bargh JD , Walsh SJ , Ashman N , Isidro-Llobet A , Carroll JS , Spring DR . Bargh JD , et al. Among authors: spring dr. Chem Commun (Camb). 2021 Apr 11;57(28):3457-3460. doi: 10.1039/d1cc00957e. Epub 2021 Mar 9. Chem Commun (Camb). 2021. PMID: 33687404

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