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An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy.
Huffman JE, Gaziano L, Al Sayed ZR, Judy RL, Raffield LM, Biddinger KJ, Charest B, Chopra A, Gagnon D, Guo X, Koledova V, Levin MG, Min YI, Pirruccello JP, Reza N, Ruan R, Verma SS, Venkatesh BA, Verma A, Yao J, Carr JJ, Casas JP, Cho K, Lima JAC, Post WS, Rader DJ, Ritchie MD, Shah A, Taylor KD, Terry JG, Rich SS, O'Donnell CJ, Phillips LS, Lunetta KL, Rotter JI, Wilson PWF, Gaziano JM, Damrauer SM; VA Million Veteran Program; Sun YV, Ellinor PT, Joseph J, Aragam KG. Huffman JE, et al. Among authors: rich ss. Nat Genet. 2025 Oct 31. doi: 10.1038/s41588-025-02372-2. Online ahead of print. Nat Genet. 2025. PMID: 41174181
Participant characteristics in the effectiveness of lifestyle interventions to optimize gestational weight gain: a systematic review and meta-analysis.
Grieger JA, Takele WW, Vesco KK, Redman LM, Hannah W, Bonham MP, Chen M, Chivers SC, Fawcett AJ, Habibi N, Liu K, Mekonnen EG, Pathirana M, Quinteros A, Taylor R, Ukke GG, Zhou SJ; ADA/EASD PMDI; Josefson J, Lim S. Grieger JA, et al. Commun Med (Lond). 2025 Oct 24;5(1):439. doi: 10.1038/s43856-025-01049-5. Commun Med (Lond). 2025. PMID: 41136661 Free PMC article.
Association of Epigenetic Age Acceleration and Mitochondrial DNA-Based Aging Metrics Provides Insights Into Mechanisms of Aging-Related Diseases.
Wang M, Zheng Y, Lai M, Saake E, Liu X, Guo X, Taylor KD, Huan T, Joehanes R, Nannini DR, Zhang K, Lake NJ, Castellani CA, Rich SS, Rotter JI, Liu Y, Raffield LM, Carson AP, Fornage M, Ma J, Arking DE, Hou L, Levy D, Liu C. Wang M, et al. Among authors: rich ss. Aging Cell. 2025 Oct 24:e70279. doi: 10.1111/acel.70279. Online ahead of print. Aging Cell. 2025. PMID: 41132105 Free article.
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.
Weinstock JS, Chaudhry SA, Ioannou M, Viskadourou M, Reventun P, Jakubek YA, Liggett LA, Laurie C, Broome JG, Khan A, Taylor KD, Guo X, Peyser PA, Boerwinkle E, Chami N, Kenny EE, Loos RJ, Psaty BM, Tracy RP, Brody JA, Yun JH, Cho MH, Vasan RS, Kardia SL, Smith JA, Raffield LM, Bidulescu A, O'Brien EC, de Andrade M, Rotter JI, Rich SS, Tracy RP, Chen YI, Gu CC, Hsiung CA, Kooperberg C, Haring B, Nassir R, Mathias R, Reiner A, Sankaran VG, Lowenstein CJ, Blackwell TW, Abecasis GR, Smith AV, Kang HM, Natarajan P, Jaiswal S, Bick A, Post WS, Scheet P, Auer P, Karantanos T, Battle A, Arvanitis M. Weinstock JS, et al. Among authors: rich ss. Nat Commun. 2025 Oct 16;16(1):9194. doi: 10.1038/s41467-025-64236-x. Nat Commun. 2025. PMID: 41102182 Free PMC article.
Admixture Mapping Analysis Reveals Genetic Determinants of the Human Plasma Proteome.
Cruz DE, Deng S, Tahir UA, Chen ZZ, Benson MD, Tuftin B, Chen J, Farrell L, Shen D, Meyer M, Lange E, Gao Y, Hall ME, Tracy RP, Rich SS, Taylor K, Manichaikul A, Rotter JI, Sofer T, Wilson JG, Gerszten RE, Raffield LM; National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium. Cruz DE, et al. Among authors: rich ss. HGG Adv. 2025 Oct 8:100529. doi: 10.1016/j.xhgg.2025.100529. Online ahead of print. HGG Adv. 2025. PMID: 41069105 Free article.
Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease.
Kim D, Highland HM, Smit RAJ, Hysong MR, Buchanan VL, Young KL, Zhao C, Spracklen CN, Kilpeläinen TO, Guo B, Darst BF, Cai Y, Wang Z, Lundin J, Berndt SI, Manson JE, Marouli E, Lange L, Lange E, Fornage M, Gignoux CR, Haiman CA, Rich SS, Buyske S, Loos RJF, Kooperberg C, Peters U, Avery CL, Gordon-Larsen P, Graff M, Raffield LM, North KE. Kim D, et al. Among authors: rich ss. Genome Med. 2025 Oct 6;17(1):113. doi: 10.1186/s13073-025-01522-9. Genome Med. 2025. PMID: 41053791 Free PMC article.
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.
Guo B, Cai Y, Kim D, Smit RAJ, Wang Z, Iyer KR, Hilliard AT, Haessler J, Tao R, Broadaway KA, Wang Y, Pozdeyev N, Stæger FF, Yang C, Vanderwerff B, Patki AD, Stalbow L, Lin M, Rafaels N, Shortt J, Wiley L, Stanislawski M, Pattee J, Davis L, Straub PS, Shuey MM, Cox NJ, Lee NR, Jørgensen ME, Bjerregaard P, Larsen C, Hansen T, Moltke I, Meigs JB, Stram DO, Yin X, Zhou X, Chang KM, Clarke SL, Guarischi-Sousa R, Lankester J, Tsao PS, Buyske S, Graff M, Raffield LM, Sun Q, Wilkens LR, Carlson CS, Easton CB, Liu S, Manson JE, Marchand LL, Haiman CA, Mohlke KL, Gordon-Larsen P, Albrechtsen A, Boehnke M, Rich SS, Manichaikul A, Rotter JI, Yousri NA, Irvin RM; biobank at the Colorado Center for Personalized Medicine (CCPM); VA Million Veteran Program (MVP); Gignoux C, North KE, Loos RJF, Assimes TL, Peters U, Kooperberg C, Raghavan S, Highland HM, Darst BF. Guo B, et al. Among authors: rich ss. Nat Commun. 2025 Oct 1;16(1):8632. doi: 10.1038/s41467-025-63546-4. Nat Commun. 2025. PMID: 41034193 Free PMC article.
1,044 results