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The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration.
Göttert S, Thiele Orberg E, Fan K, Heinrich P, Matthe DM, Khalid O, Klostermeier L, Suriano C, Strieder N, Gebhard C, Vonbrunn E, Mamilos A, Hirsch D, Meedt E, Kleigrewe K, Hiergeist A, Schwarz A, Gläsner J, Ghimire S, Joachim L, Voll F, Neuhaus K, Janssen KP, Perl M, Pielmeier F, Ruland J, Kreutz M, Weber D, Schmidl C, Köhler N, Tschurtschenthaler M, Hoffmann P, Edinger M, Wolff D, Bassermann F, Rehli M, Haller D, Evert M, Hildner K, Büttner-Herold M, Herr W, Gessner A, Heidegger S, Holler E, Poeck H. Göttert S, et al. Among authors: perl m. Nat Commun. 2025 Oct 20;16(1):9282. doi: 10.1038/s41467-025-65180-6. Nat Commun. 2025. PMID: 41115965 Free PMC article.
Sustained allogeneic kidney graft operational tolerance despite discontinued conventional immunosuppression after CD19-CAR-T cell therapy for relapsed/refractory posttransplant lymphoproliferative disorder.
Hansmann H, Henkel C, Fante MA, Harrer DC, Heidemanns S, Oellerich M, Beck J, Schütz E, Biswenger V, Perl M, Zartner B, Edinger M, Wolff D, Hoffmann P, Herr W, Banas B, Zecher D, Hansmann L. Hansmann H, et al. Among authors: perl m. Am J Transplant. 2025 Sep 17:S1600-6135(25)02986-7. doi: 10.1016/j.ajt.2025.09.009. Online ahead of print. Am J Transplant. 2025. PMID: 40972901 Free article.
CAR-T cell therapy and reconstructive oncologic surgery in peripheral solid tumors-A narrative review.
Knoedler L, Herfeld K, Schaefer DA, Diatta F, Clune J, Evans B, Seu M, Kim BS, Alfertshofer M, Schaschinger T, Iske J, Knoedler S, Lellouch AG, Jeljeli M, Carturan A, Ruella M, Heiland M, Poeck H, Perl M, Pomahac B, Kauke-Navarro M. Knoedler L, et al. Among authors: perl m. Cell Rep Med. 2025 Aug 19;6(8):102240. doi: 10.1016/j.xcrm.2025.102240. Epub 2025 Jul 16. Cell Rep Med. 2025. PMID: 40675157 Free PMC article. Review.
Gasdermin E links tumor cell-intrinsic nucleic acid signaling to proinflammatory cell death for successful checkpoint inhibitor cancer immunotherapy.
Enssle S, Sax A, May P, El Khawanky N, Soliman N, Perl M, Enssle JC, Krey K, Ruland J, Pichlmair A, Bassermann F, Poeck H, Heidegger S. Enssle S, et al. Among authors: perl m. Oncoimmunology. 2025 Dec;14(1):2504244. doi: 10.1080/2162402X.2025.2504244. Epub 2025 May 14. Oncoimmunology. 2025. PMID: 40366863 Free PMC article.
467 results