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CDK7-targeted therapy effectively disrupts cell cycle progression and oncogenic signaling in head and neck cancer.
Otero-Rosales M, Álvarez-González M, Pazos I, de Luxán-Delgado B, Del Marro S, Pozo-Agundo E, Rodríguez-Santamaría M, López-Fernández A, Corte-Torres D, Granda-Díaz R, Álvarez-Teijeiro S, Fernández-Vega I, Lorz C, García-Escudero R, Rodrigo JP, Tzelepis K, Vassiliou G, Ferrer I, Álvarez-Fernández M, García-Pedrero JM, Hermida-Prado F. Otero-Rosales M, et al. Among authors: ferrer i. Signal Transduct Target Ther. 2025 Nov 6;10(1):363. doi: 10.1038/s41392-025-02452-z. Signal Transduct Target Ther. 2025. PMID: 41193441 Free PMC article.
YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
Garmendia I, Pajares MJ, Hermida-Prado F, Ajona D, Bértolo C, Sainz C, Lavín A, Remírez AB, Valencia K, Moreno H, Ferrer I, Behrens C, Cuadrado M, Paz-Ares L, Bustelo XR, Gil-Bazo I, Alameda D, Lecanda F, Calvo A, Felip E, Sánchez-Céspedes M, Wistuba II, Granda-Diaz R, Rodrigo JP, García-Pedrero JM, Pio R, Montuenga LM, Agorreta J. Garmendia I, et al. Among authors: ferrer i. Am J Respir Crit Care Med. 2019 Oct 1;200(7):888-899. doi: 10.1164/rccm.201807-1292OC. Am J Respir Crit Care Med. 2019. PMID: 31166114 Free article.
YES1 Is a Druggable Oncogenic Target in SCLC.
Redin E, Garrido-Martin EM, Valencia K, Redrado M, Solorzano JL, Carias R, Echepare M, Exposito F, Serrano D, Ferrer I, Nunez-Buiza A, Garmendia I, García-Pedrero JM, Gurpide A, Paz-Ares L, Politi K, Montuenga LM, Calvo A. Redin E, et al. Among authors: ferrer i. J Thorac Oncol. 2022 Dec;17(12):1387-1403. doi: 10.1016/j.jtho.2022.08.002. Epub 2022 Aug 18. J Thorac Oncol. 2022. PMID: 35988891 Free article.
Current Challenges in Cancer Treatment.
Zugazagoitia J, Guedes C, Ponce S, Ferrer I, Molina-Pinelo S, Paz-Ares L. Zugazagoitia J, et al. Among authors: ferrer i. Clin Ther. 2016 Jul;38(7):1551-66. doi: 10.1016/j.clinthera.2016.03.026. Epub 2016 May 2. Clin Ther. 2016. PMID: 27158009 Review.
Prospective Clinical Integration of an Amplicon-Based Next-Generation Sequencing Method to Select Advanced Non-Small-Cell Lung Cancer Patients for Genotype-Tailored Treatments.
Zugazagoitia J, Rueda D, Carrizo N, Enguita AB, Gómez-Sánchez D, Díaz-Serrano A, Jiménez E, Mérida A, Calero R, Lujan R, De Miguel E, Gámez P, Díaz-Hellín V, Nuñez JA, Iglesias L, Ferrer I, Paz-Ares L, Ponce-Aix S. Zugazagoitia J, et al. Among authors: ferrer i. Clin Lung Cancer. 2018 Jan;19(1):65-73.e7. doi: 10.1016/j.cllc.2017.06.008. Epub 2017 Jun 23. Clin Lung Cancer. 2018. PMID: 28780976
A patent review of FGFR4 selective inhibition in cancer (2007-2018).
Quintanal-Villalonga A, Ferrer I, Molina-Pinelo S, Paz-Ares L. Quintanal-Villalonga A, et al. Among authors: ferrer i. Expert Opin Ther Pat. 2019 May 30;29(6):429-438. doi: 10.1080/13543776.2019.1624720. Print 2019 Jun. Expert Opin Ther Pat. 2019. PMID: 31146605 Review.
FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy.
Quintanal-Villalonga Á, Ferrer I, Guruceaga E, Cirauqui C, Marrugal Á, Ojeda L, García S, Zugazagoitia J, Muñoz-Galván S, Lopez-Rios F, Montuenga L, Vicent S, Molina-Pinelo S, Carnero A, Paz-Ares L. Quintanal-Villalonga Á, et al. Among authors: ferrer i. EBioMedicine. 2020 Mar;53:102683. doi: 10.1016/j.ebiom.2020.102683. Epub 2020 Feb 27. EBioMedicine. 2020. PMID: 32114392 Free PMC article.
1,372 results