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CDK7-targeted therapy effectively disrupts cell cycle progression and oncogenic signaling in head and neck cancer.
Otero-Rosales M, Álvarez-González M, Pazos I, de Luxán-Delgado B, Del Marro S, Pozo-Agundo E, Rodríguez-Santamaría M, López-Fernández A, Corte-Torres D, Granda-Díaz R, Álvarez-Teijeiro S, Fernández-Vega I, Lorz C, García-Escudero R, Rodrigo JP, Tzelepis K, Vassiliou G, Ferrer I, Álvarez-Fernández M, García-Pedrero JM, Hermida-Prado F. Otero-Rosales M, et al. Among authors: pazos i. Signal Transduct Target Ther. 2025 Nov 6;10(1):363. doi: 10.1038/s41392-025-02452-z. Signal Transduct Target Ther. 2025. PMID: 41193441 Free PMC article.
Single-Molecule Biodosimetry.
Lamontagne M, Newell SM, Pazos IM, Tosh RE, Polf JC, Zwolak M, Robertson JWF. Lamontagne M, et al. Among authors: pazos im. Anal Chem. 2025 Oct 14;97(40):22004-22012. doi: 10.1021/acs.analchem.5c03303. Epub 2025 Aug 20. Anal Chem. 2025. PMID: 40835481 Free PMC article.
Interleukin-11 promotes lung adenocarcinoma tumourigenesis and immune evasion.
Cirauqui C, Ojeda L, Otano I, Pazos I, Santos A, Garrido-Martín EM, Yagüe P, Ramos-Paradas J, Molina-Pinelo S, Roncador G, Solórzano JL, Muñoz MT, Cozar P, Plaza P, Suárez R, Jiménez M, Moreno R, Rosado A, Gámez P, García-Luján R, Zugazagoitia J, Sweet-Cordero EA, Barbacid M, Carnero A, Ferrer I, Paz-Ares L. Cirauqui C, et al. Among authors: pazos i. Clin Transl Med. 2025 Jul;15(7):e70374. doi: 10.1002/ctm2.70374. Clin Transl Med. 2025. PMID: 40673604 Free PMC article.
Real-Life Experience of HER2 (Human Epidermal Growth Factor Receptor 2)-Positive Advanced Breast Cancer Patients Treated With T-DXd (Trastuzumab Deruxtecan): A Multicentric Portuguese Study.
Bizarro R, Pazos I, Teixeira A, Pereira M, Gonçalves J, Abreu C, Ferreira R, Oliveira S, Duarte Mendes A, Eiriz I, Santiago M, Teixeira C, Leitão M, Guedes H, Bento S, Inácio M, Alpoim T, Correia J, Branco F, Passos-Coelho J, Casa-Nova M, Teixeira JA. Bizarro R, et al. Among authors: pazos i. Cureus. 2025 Feb 27;17(2):e79734. doi: 10.7759/cureus.79734. eCollection 2025 Feb. Cureus. 2025. PMID: 40161117 Free PMC article.
The P4-ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast.
Pazos I, Puig-Tintó M, Betancur L, Cordero J, Jiménez-Menéndez N, Abella M, Hernández AC, Duran AG, Adachi-Fernández E, Belmonte-Mateos C, Sabido-Bozo S, Tosi S, Nezu A, Oliva B, Colombelli J, Graham TR, Yoshimori T, Muñiz M, Hamasaki M, Gallego O. Pazos I, et al. EMBO Rep. 2023 May 4;24(5):e56134. doi: 10.15252/embr.202256134. Epub 2023 Mar 16. EMBO Rep. 2023. PMID: 36929574 Free PMC article.
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