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572 results

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Page 1
Industrialization drives convergent microbial and physiological shifts in the human metaorganism.
Poyet M, Rühlemann M, Schaan AP, Ma Y, Moitinho-Silva L, Wacker EM, Jebens H, Patel L, Nguyen LTT, Zimmer A, Plichta D, McDonald D, Stevens C, Agyei A, Afihene MY, Asibey SO, Awuku YA, Badiane AS, Ching LS, Corzett C, Deme A, Dominguez-Rodrigo M, Duah A, Fezeu A, Froment A, Gibbons S, Girard C, Hooker J, Ibrahim F, Iqaluk D, Juimo V, Kettunen P, Lafosse S, Lango-Yaya E, Lehtimäki J, Lim YAL, Mabulla A, Mahachai V, Mohamed RS, Moniz K, Mwikarago IE, Nartey YA, Ndiaye D, Noel M, Onyekwere C, Pin TM, Plymoth A, Roberts L, Ruokolainen L, Rusine J, Segurel L, Shapiro BJ, Sigwazi S, Sistiaga A, Valles K, Vatanen T, Vilaichone RK, Rosenstiel P, Baines J, Franke A, Ellinghaus D, Knight R, Daly M, Xavier RJ, Alm EJ, Groussin M. Poyet M, et al. Among authors: xavier rj. bioRxiv [Preprint]. 2025 Oct 20:2025.10.20.683358. doi: 10.1101/2025.10.20.683358. bioRxiv. 2025. PMID: 41280098 Free PMC article. Preprint.
Convergent genomic responses of human gut bacteria to variations in industrialization.
Rühlemann M, Szánthó LL, Waschina S, Moitinho-Silva L, Mews LK, Camarena JF, Jebens H, Costa J, Juimo V, Fezeu A, Agyei A, Afihene MY, Asibey SO, Awuku YA, Duah A, Nartey YA, Ibrahim F, Lim YAL, Pin TM, Onyekwere C, Rusine J, Mwikarago IE, Baines J, Franke A, Szöllősi GJ, Xavier R, Alm EJ, Groussin M, Poyet M. Rühlemann M, et al. bioRxiv [Preprint]. 2025 Oct 20:2025.10.20.683395. doi: 10.1101/2025.10.20.683395. bioRxiv. 2025. PMID: 41278887 Free PMC article. Preprint.
Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes.
Ogasawara D, Konrad DB, Tan ZY, Carey KL, Luo J, Won SJ, Li H, Carter T, DeMeester KE, Njomen E, Schreiber SL, Xavier RJ, Melillo B, Cravatt BF. Ogasawara D, et al. Among authors: xavier rj. bioRxiv [Preprint]. 2024 Feb 29:2024.02.27.582206. doi: 10.1101/2024.02.27.582206. bioRxiv. 2024. Update in: Cell Chem Biol. 2024 Dec 19;31(12):2138-2155.e32. doi: 10.1016/j.chembiol.2024.10.005. PMID: 38464067 Free PMC article. Updated. Preprint.
Trajectories of microbiome-derived bile acids in early life - insights into the progression to islet autoimmunity.
Lamichhane S, Dickens AM, Buchacher T, Lou ET, Charron-Lamoureux V, Kattelus R, Karmacharya P, Pinto da Silva L, Kråkström M, Rasool O, Sen P, Walker C, Patan A, Gentry EC, Arzoomand A, Lakshmikanth T, Mikeš J, Mebrahtu A, Vatanen T, Raffatellu M, Zengler K, Hyötyläinen T, Xavier RJ, Brodin P, Lahesmaa R, Dorrestein PC, Knip M, Orešič M. Lamichhane S, et al. Among authors: xavier rj. medRxiv [Preprint]. 2025 Feb 24:2025.02.18.25322275. doi: 10.1101/2025.02.18.25322275. medRxiv. 2025. Update in: Nat Commun. 2025 Dec 3;17(1):38. doi: 10.1038/s41467-025-66619-6. PMID: 40061321 Free PMC article. Updated. Preprint.
Composition and Function of the Gut Microbiome in Microscopic Colitis.
Chen AS, Kim H, Nzabarushimana E, Shen J, Williams K, Gurung J, McGoldrick J, Burke KE, Nguyen LH, Staller K, Chung DC, Xavier RJ, Khalili H. Chen AS, et al. Among authors: xavier rj. medRxiv [Preprint]. 2024 Oct 29:2024.10.28.24316293. doi: 10.1101/2024.10.28.24316293. medRxiv. 2024. Update in: Nat Commun. 2025 May 23;16(1):4644. doi: 10.1038/s41467-025-59566-9. PMID: 39574841 Free PMC article. Updated. Preprint.
A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity.
Slowikowski K, Sen P, Cosgriff CV, Tantivit J, Eisenhaure T, LaSalle TJ, Manakongtreecheep K, Tirard A, Arnold BY, Pacheco-Navarro A, Yang EY, Reyes M, Gonye A, Gushterova I, Russo B, Rojas-Lopez M, Sharma N, Thomas MF, Sharova T, Frederick D, Lavin-Parsons K, Lilley B, McKaig B, Lodenstein C, Khanna H, Kays K, Charland N, Smith N, Ramesh S, Delorey TM, Phillips D, Amir-Zilberstein L, Brown EM, Benson M, Park SM, Tusi BK, Pokatayev V, Hecht C, Pishesha N, Woolley AE, Cosimi L, Rozenblatt-Rosen O, Bod L, Blainey PC, Regev A, Deguine J, Xavier R, Hung D, Boland GM, Bhattacharyya RP, Utz PJ, Goldberg MB, Mansour MK, Filbin MR, Sade-Feldman M, Hacohen N, Villani AC. Slowikowski K, et al. medRxiv [Preprint]. 2025 Sep 21:2025.09.19.25334095. doi: 10.1101/2025.09.19.25334095. medRxiv. 2025. PMID: 41332837 Free PMC article. Preprint.
Microbiota-mediated induction of beige adipocytes in response to dietary cues.
Tanoue T, Nagayama M, Roochana AJA, Zimmerman S, Ashenberg O, Jain T, Igarashi R, Sasajima S, Takeshita K, Hetherington N, Okahashi N, Ueda M, Konishi M, Nakayama Y, Minoda A, Skelly AN, Minokoshi Y, Pucci N, Mende DR, Arita M, Yamamoto H, Watanabe S, Miura K, Behie SW, Suda W, Sato T, Atarashi K, Matsushita M, Kajimura S, Plichta DR, Saito M, Xavier RJ, Honda K. Tanoue T, et al. Among authors: xavier rj. Nature. 2026 Mar 4. doi: 10.1038/s41586-026-10205-3. Online ahead of print. Nature. 2026. PMID: 41781619
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk.
Reeve MP, Kanai M, Graham DB, Karjalainen J, Luo S, Kolosov N, Adams C, Ritari J, Karczewski KJ, Kiiskinen T, Jiang Y, Fuller Z, Mehtonen J, Kurki MI, Khan Z; FinnGen; Partanen J, McCarthy MI, Artomov M, Palotie A, Tuomi T, Pirinen M, Kero J, Xavier RJ, Daly MJ, Ripatti S. Reeve MP, et al. Among authors: xavier rj. Nat Genet. 2026 Mar;58(3):550-559. doi: 10.1038/s41588-026-02521-1. Epub 2026 Feb 26. Nat Genet. 2026. PMID: 41748903 Free PMC article.
Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis.
Fiskin E, Eraslan G, Alora-Palli MB, Jain T, Leyva-Castillo JM, Kim S, Choe H, Lareau CA, Lau H, Finan EP, Teixeira-Soldano I, LaBere B, Chu A, Woods B, Chou J, Slyper M, Waldman J, Islam S, Schneider L, Phipatanakul W, Platt C, Rozenblatt-Rosen O, Delorey TM, Ashenberg O, Deguine J, Smith GP, Geha RS, Regev A, Xavier RJ. Fiskin E, et al. Among authors: xavier rj. Nat Commun. 2026 Feb 25. doi: 10.1038/s41467-026-69587-7. Online ahead of print. Nat Commun. 2026. PMID: 41741455 Free article.
572 results