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Page 1
Site-selective modification strategies in antibody-drug conjugates.
Walsh SJ , Bargh JD , Dannheim FM , Hanby AR , Seki H , Counsell AJ , Ou X , Fowler E , Ashman N , Takada Y , Isidro-Llobet A , Parker JS , Carroll JS , Spring DR . Walsh SJ , et al. Among authors: spring dr. Chem Soc Rev. 2021 Jan 21;50(2):1305-1353. doi: 10.1039/d0cs00310g. Epub 2020 Dec 8. Chem Soc Rev. 2021. PMID: 33290462 Review.
A dual-enzyme cleavable linker for antibody-drug conjugates.
Bargh JD , Walsh SJ , Ashman N , Isidro-Llobet A , Carroll JS , Spring DR . Bargh JD , et al. Among authors: spring dr. Chem Commun (Camb). 2021 Apr 11;57(28):3457-3460. doi: 10.1039/d1cc00957e. Epub 2021 Mar 9. Chem Commun (Camb). 2021. PMID: 33687404
Sulfatase-cleavable linkers for antibody-drug conjugates.
Bargh JD, Walsh SJ, Isidro-Llobet A, Omarjee S, Carroll JS, Spring DR. Bargh JD, et al. Among authors: spring dr. Chem Sci. 2020 Jan 27;11(9):2375-2380. doi: 10.1039/c9sc06410a. Chem Sci. 2020. PMID: 34084399 Free PMC article.
Rapid and robust cysteine bioconjugation with vinylheteroarenes.
Seki H, Walsh SJ, Bargh JD, Parker JS, Carroll J, Spring DR. Seki H, et al. Among authors: spring dr. Chem Sci. 2021 Jun 7;12(26):9060-9068. doi: 10.1039/d1sc02722k. eCollection 2021 Jul 7. Chem Sci. 2021. PMID: 34276935 Free PMC article.
Non-internalising antibody-drug conjugates.
Ashman N, Bargh JD, Spring DR. Ashman N, et al. Among authors: spring dr. Chem Soc Rev. 2022 Nov 14;51(22):9182-9202. doi: 10.1039/d2cs00446a. Chem Soc Rev. 2022. PMID: 36322071 Review.
239 results