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A Multi-Step Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma.
Xu X, Liu X, Jarajapu V, Neelature Sriramareddy S, Konecny F, Posorske B, Dollar JJ, Liu X, Jasani N, Wang K, Mecozzi N, Soto-Vargas Z, Ochoa-Rios SL, Murikipudi H, Phan N, Chadourne M, Kuznetsoff JN, Sinard J, Bennett RL, Licht JD, Smalley KSM, Harbour JW, Yu X, Karreth FA. Xu X, et al. Among authors: ochoa rios sl. Cancer Res. 2026 Feb 9:10.1158/0008-5472.CAN-25-2684. doi: 10.1158/0008-5472.CAN-25-2684. Online ahead of print. Cancer Res. 2026. PMID: 41661679 Free PMC article.
FRA1 drives melanoma metastasis through an actionable transcriptional network.
Xu X, Jarajapu V, Chadourne M, Soto-Vargas Z, Ochoa-Rios SL, Jasani N, Wang K, Mecozzi N, Yao J, Yu X, Karreth FA. Xu X, et al. Among authors: ochoa rios sl. Oncogene. 2025 Dec;44(50):4895-4909. doi: 10.1038/s41388-025-03632-5. Epub 2025 Nov 24. Oncogene. 2025. PMID: 41286309 Free PMC article.