Modification in framework region I results in a decreased affinity of chimeric anti-TAG72 antibody.
Xiang JH, Roder J, Pan ZG, Roifman C, Hozumi N.
Xiang JH, et al. Among authors: roder j.
Mol Immunol. 1991 Jan-Feb;28(1-2):141-8. doi: 10.1016/0161-5890(91)90097-4.
Mol Immunol. 1991.
PMID: 2011123
A mouse/human chimeric B72.3P-1-6 antibody was produced by construction of a novel expression vector mpSV2neo-EP2-V-Crl containing the same gene fragments as the expression vector mpSV2neo-EP1-V-Crl (Xiang J., Roder J. and Hozunni N., submitted to Molec. Immu …
A mouse/human chimeric B72.3P-1-6 antibody was produced by construction of a novel expression vector mpSV2neo-EP2-V-Crl containing the same …