Generation of a potent & selective series of IRAK4 inhibitors based on a structure based, hybridization approach.
Terstiege I, Aagaard A, Berggren K, Bird J, Cumming IA, Groombridge SD, Hidestål L, Johannesson P, Korsgren P, Leuchowius KJ, Lundqvist S, Scott JS, Xue Y, Degorce SL.
Terstiege I, et al. Among authors: scott js.
Bioorg Med Chem. 2025 Dec 15;131:118333. doi: 10.1016/j.bmc.2025.118333. Epub 2025 Jul 28.
Bioorg Med Chem. 2025.
PMID: 40972347