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Page 1
Risk profiles for genital infection in women.
Evans BA, Tasker T, MacRae KD. Evans BA, et al. Among authors: tasker t. Genitourin Med. 1993 Aug;69(4):257-61. doi: 10.1136/sti.69.4.257. Genitourin Med. 1993. PMID: 7721283 Free PMC article.
Continuous co-treatment of mine drainage with municipal wastewater.
Spellman CD, Burton ZT, Ikuma K, Strosnider WHJ, Tasker TL, Roman B, Goodwill JE. Spellman CD, et al. Among authors: tasker tl. J Environ Manage. 2024 Mar;354:120282. doi: 10.1016/j.jenvman.2024.120282. Epub 2024 Feb 15. J Environ Manage. 2024. PMID: 38364535
A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease.
Nathan PJ, Millais SB, Godwood A, Dewit O, Cross DM, Liptrot J, Ruparelia B, Jones SP, Bakker G, Maruff PT, Light GA, Brown AJH, Weir MP, Congreve M, Tasker T. Nathan PJ, et al. Among authors: tasker t. Alzheimers Dement (N Y). 2022 Feb 23;8(1):e12273. doi: 10.1002/trc2.12273. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35229025 Free PMC article.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: tasker t. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free PMC article. Clinical Trial.
Safety and Pharmacokinetics of HTL0018318, a Novel M1 Receptor Agonist, Given in Combination with Donepezil at Steady State: A Randomized Trial in Healthy Elderly Subjects.
Bakker C, van der Aart J, Labots G, Liptrot J, Cross DM, Klaassen ES, Dickinson S, Tasker T, Groeneveld GJ. Bakker C, et al. Among authors: tasker t. Drugs R D. 2021 Sep;21(3):295-304. doi: 10.1007/s40268-021-00352-5. Epub 2021 Jun 23. Drugs R D. 2021. PMID: 34164794 Free PMC article. Clinical Trial.
Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1 -acetylcholine receptor agonist: A randomized cross-over trial.
Bakker C, Prins S, Liptrot J, Hart EP, Klaassen ES, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Stevens J, Cross DM, Tasker T, Nathan PJ, Groeneveld GJ. Bakker C, et al. Among authors: tasker t. Br J Clin Pharmacol. 2021 Nov;87(11):4439-4449. doi: 10.1111/bcp.14872. Epub 2021 May 8. Br J Clin Pharmacol. 2021. PMID: 33891333 Free PMC article. Clinical Trial.
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