Geahlen RL - Search Results

1

Atherton-Fessler S, Parker LL, Geahlen RL, Piwnica-Worms H. Atherton-Fessler S, et al. Among authors: geahlen rl. Mol Cell Biol. 1993 Mar;13(3):1675-85. doi: 10.1128/mcb.13.3.1675-1685.1993. Mol Cell Biol. 1993. PMID: 8441405 Free PMC article.

2

A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition.

Lipchik AM, Killins RL, Geahlen RL, Parker LL. Lipchik AM, et al. Among authors: geahlen rl. Biochemistry. 2012 Sep 25;51(38):7515-24. doi: 10.1021/bi300970h. Epub 2012 Sep 12. Biochemistry. 2012. PMID: 22920457 Free PMC article.

3

Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular stores.

Martin VA, Wang WH, Lipchik AM, Parker LL, He Y, Zhang S, Zhang ZY, Geahlen RL. Martin VA, et al. Among authors: geahlen rl. Cell Signal. 2012 May;24(5):1064-73. doi: 10.1016/j.cellsig.2012.01.001. Epub 2012 Jan 11. Cell Signal. 2012. PMID: 22261254 Free PMC article.

4

A quantitative proteomics-based competition binding assay to characterize pITAM-protein interactions.

Hu L, Yang L, Lipchik AM, Geahlen RL, Parker LL, Tao WA. Hu L, et al. Among authors: geahlen rl. Anal Chem. 2013 May 21;85(10):5071-7. doi: 10.1021/ac400359t. Epub 2013 May 8. Anal Chem. 2013. PMID: 23611696 Free PMC article.

5

Selective inhibition of the growth of ras-transformed human bronchial epithelial cells by emodin, a protein-tyrosine kinase inhibitor.

Chan TC, Chang CJ, Koonchanok NM, Geahlen RL. Chan TC, et al. Among authors: geahlen rl. Biochem Biophys Res Commun. 1993 Jun 30;193(3):1152-8. doi: 10.1006/bbrc.1993.1746. Biochem Biophys Res Commun. 1993. PMID: 7686746

6

Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.

Zhou YJ, Magnuson KS, Cheng TP, Gadina M, Frucht DM, Galon J, Candotti F, Geahlen RL, Changelian PS, O'Shea JJ. Zhou YJ, et al. Among authors: geahlen rl. Mol Cell Biol. 2000 Jun;20(12):4371-80. doi: 10.1128/MCB.20.12.4371-4380.2000. Mol Cell Biol. 2000. PMID: 10825200 Free PMC article.

7

Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by Syk tyrosine kinase.

Groesch TD, Zhou F, Mattila S, Geahlen RL, Post CB. Groesch TD, et al. Among authors: geahlen rl. J Mol Biol. 2006 Mar 10;356(5):1222-36. doi: 10.1016/j.jmb.2005.11.095. Epub 2005 Dec 27. J Mol Biol. 2006. PMID: 16410013

8

The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.

Li M, Ong SS, Rajwa B, Thieu VT, Geahlen RL, Harrison ML. Li M, et al. Among authors: geahlen rl. Mol Cell Biol. 2008 Jan;28(2):630-41. doi: 10.1128/MCB.00150-07. Epub 2007 Nov 12. Mol Cell Biol. 2008. PMID: 17998336 Free PMC article.

9

Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.

Chen CH, Martin VA, Gorenstein NM, Geahlen RL, Post CB. Chen CH, et al. Among authors: geahlen rl. Mol Cell Biol. 2011 Jul;31(14):2984-96. doi: 10.1128/MCB.05043-11. Epub 2011 May 23. Mol Cell Biol. 2011. PMID: 21606197 Free PMC article.

10

Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival.

Wang WH, Childress MO, Geahlen RL. Wang WH, et al. Among authors: geahlen rl. Mol Cell Biol. 2014 Oct;34(20):3788-99. doi: 10.1128/MCB.00937-14. Epub 2014 Aug 4. Mol Cell Biol. 2014. PMID: 25092868 Free PMC article.

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