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Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase.
Gallagher TF, Seibel GL, Kassis S, Laydon JT, Blumenthal MJ, Lee JC, Lee D, Boehm JC, Fier-Thompson SM, Abt JW, Soreson ME, Smietana JM, Hall RF, Garigipati RS, Bender PE, Erhard KF, Krog AJ, Hofmann GA, Sheldrake PL, McDonnell PC, Kumar S, Young PR, Adams JL. Gallagher TF, et al. Among authors: sheldrake pl. Bioorg Med Chem. 1997 Jan;5(1):49-64. doi: 10.1016/s0968-0896(96)00212-x. Bioorg Med Chem. 1997. PMID: 9043657
1-substituted 4-aryl-5-pyridinylimidazoles: a new class of cytokine suppressive drugs with low 5-lipoxygenase and cyclooxygenase inhibitory potency.
Boehm JC, Smietana JM, Sorenson ME, Garigipati RS, Gallagher TF, Sheldrake PL, Bradbeer J, Badger AM, Laydon JT, Lee JC, Hillegass LM, Griswold DE, Breton JJ, Chabot-Fletcher MC, Adams JL. Boehm JC, et al. Among authors: sheldrake pl. J Med Chem. 1996 Sep 27;39(20):3929-37. doi: 10.1021/jm960415o. J Med Chem. 1996. PMID: 8831759