Block TM - Search Results

1

Treatment of chronic hepadnavirus infection in a woodchuck animal model with an inhibitor of protein folding and trafficking.

Block TM, Lu X, Mehta AS, Blumberg BS, Tennant B, Ebling M, Korba B, Lansky DM, Jacob GS, Dwek RA. Block TM, et al. Nat Med. 1998 May;4(5):610-4. doi: 10.1038/nm0598-610. Nat Med. 1998. PMID: 9585237 Clinical Trial.

2

Evidence that N-linked glycosylation is necessary for hepatitis B virus secretion.

Lu X, Mehta A, Dwek R, Butters T, Block T. Lu X, et al. Virology. 1995 Nov 10;213(2):660-5. doi: 10.1006/viro.1995.0038. Virology. 1995. PMID: 7491790 Free article.

3

Role of glycan processing in hepatitis B virus envelope protein trafficking.

Block TM, Lu X, Mehta A, Park J, Blumberg BS, Dwek R. Block TM, et al. Adv Exp Med Biol. 1998;435:207-16. doi: 10.1007/978-1-4615-5383-0_20. Adv Exp Med Biol. 1998. PMID: 9498079 Review. No abstract available.

4

Hepatitis B virus large and middle glycoproteins are degraded by a proteasome pathway in glucosidase-inhibited cells but not in cells with functional glucosidase enzyme.

Simsek E, Mehta A, Zhou T, Dwek RA, Block T. Simsek E, et al. J Virol. 2005 Oct;79(20):12914-20. doi: 10.1128/JVI.79.20.12914-12920.2005. J Virol. 2005. PMID: 16188993 Free PMC article.

5

The combination of interferon alpha-2b and n-butyl deoxynojirimycin has a greater than additive antiviral effect upon production of infectious bovine viral diarrhea virus (BVDV) in vitro: implications for hepatitis C virus (HCV) therapy.

Ouzounov S, Mehta A, Dwek RA, Block TM, Jordan R. Ouzounov S, et al. Among authors: block tm. Antiviral Res. 2002 Sep;55(3):425-35. doi: 10.1016/s0166-3542(02)00075-x. Antiviral Res. 2002. PMID: 12206880

6

Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ.

Mehta A, Ouzounov S, Jordan R, Simsek E, Lu X, Moriarty RM, Jacob G, Dwek RA, Block TM. Mehta A, et al. Among authors: block tm. Antivir Chem Chemother. 2002 Sep;13(5):299-304. doi: 10.1177/095632020201300505. Antivir Chem Chemother. 2002. PMID: 12630678 Free article.

7

Enhancement of infection of HepG2 cells in culture by predigestion of hepadnavirus with V8 protease.

Lu X, Block TM. Lu X, et al. Among authors: block tm. Methods Mol Med. 2004;96:199-208. doi: 10.1385/1-59259-670-3:199. Methods Mol Med. 2004. PMID: 14762271 No abstract available.

8

alpha-Glucosidase inhibitors have a prolonged antiviral effect against hepatitis B virus through the sustained inhibition of the large and middle envelope glycoproteins.

Simsek E, Lu X, Ouzounov S, Block TM, Mehta AS. Simsek E, et al. Among authors: block tm. Antivir Chem Chemother. 2006;17(5):259-67. doi: 10.1177/095632020601700503. Antivir Chem Chemother. 2006. PMID: 17176630 Free article.

9

Synovial stimulatory protein fragments copurify with woodchuck hepatitis virus: implications for the etiology of arthritis in chronic hepatitis B virus infection.

Mehta A, Lu X, Block T, Willis A, Dwek R, Tennant B, Blumberg B. Mehta A, et al. Arthritis Rheum. 2001 Feb;44(2):486-7. doi: 10.1002/1529-0131(200102)44:2<486::AID-ANR69>3.0.CO;2-P. Arthritis Rheum. 2001. PMID: 11229482 No abstract available.

10

Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited.

Lu X, Mehta A, Dadmarz M, Dwek R, Blumberg BS, Block TM. Lu X, et al. Among authors: block tm. Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2380-5. doi: 10.1073/pnas.94.6.2380. Proc Natl Acad Sci U S A. 1997. PMID: 9122203 Free PMC article.

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