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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1975 4
1976 14
1977 18
1978 23
1979 26
1980 73
1981 100
1982 158
1983 175
1984 231
1985 266
1986 274
1987 224
1988 289
1989 303
1990 363
1991 408
1992 406
1993 440
1994 470
1995 467
1996 444
1997 451
1998 397
1999 421
2000 409
2001 389
2002 382
2003 407
2004 451
2005 440
2006 447
2007 499
2008 525
2009 469
2010 520
2011 510
2012 491
2013 503
2014 478
2015 481
2016 417
2017 397
2018 377
2019 319
2020 328
2021 289
2022 297
2023 258
2024 274
2025 220

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15,792 results

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Page 1
Apo(a) and ApoB Interact Noncovalently Within Hepatocytes: Implications for Regulation of Lp(a) Levels by Modulation of ApoB Secretion.
Youssef A, Clark JR, Marcovina SM, Boffa MB, Koschinsky ML. Youssef A, et al. Arterioscler Thromb Vasc Biol. 2022 Mar;42(3):289-304. doi: 10.1161/ATVBAHA.121.317335. Epub 2022 Jan 20. Arterioscler Thromb Vasc Biol. 2022. PMID: 35045727
We used a pulse-chase metabolic labeling approach to measure apo(a) and apoB secretion rates. RESULTS: Noncovalent complexes containing apo(a)/apoB are present in lysates from cells expressing 17K but not 17KdeltaLBS7,8, whereas covalent apo( …
We used a pulse-chase metabolic labeling approach to measure apo(a) and apoB secretion rates. RESULTS: Noncovalent complexes c …
Apo A-IV: an update on regulation and physiologic functions.
Stan S, Delvin E, Lambert M, Seidman E, Levy E. Stan S, et al. Biochim Biophys Acta. 2003 Mar 17;1631(2):177-87. doi: 10.1016/s1388-1981(03)00004-0. Biochim Biophys Acta. 2003. PMID: 12633684 Review.
Apolipoprotein (apo) A-IV, first identified 28 years ago as a plasma lipoprotein moiety, is now known to participate in the regulation of various metabolic pathways. ...After entry into the bloodstream, the 46-kDa glycoprotein apo A-IV appears associat …
Apolipoprotein (apo) A-IV, first identified 28 years ago as a plasma lipoprotein moiety, is now known to participate in the re …
Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials.
Viney NJ, van Capelleveen JC, Geary RS, Xia S, Tami JA, Yu RZ, Marcovina SM, Hughes SG, Graham MJ, Crooke RM, Crooke ST, Witztum JL, Stroes ES, Tsimikas S. Viney NJ, et al. Lancet. 2016 Nov 5;388(10057):2239-2253. doi: 10.1016/S0140-6736(16)31009-1. Epub 2016 Sep 21. Lancet. 2016. PMID: 27665230 Clinical Trial.
There were two serious adverse events (myocardial infarctions) in the IONIS-APO(a)(Rx) phase 2 trial, one in the IONIS-APO(a)(Rx) and one in the placebo group, but neither were thought to be treatment related. 12% of injections with IONIS-APO( …
There were two serious adverse events (myocardial infarctions) in the IONIS-APO(a)(Rx) phase 2 trial, one in the IONIS-APO …
Apo A-IV: a new satiety signal.
Merrill AH Jr. Merrill AH Jr. Nutr Rev. 1993 Sep;51(9):273-5. doi: 10.1111/j.1753-4887.1993.tb03120.x. Nutr Rev. 1993. PMID: 8247420 Review.
Chylomicrons have a suppressive effect on food consumption, which is attributed to apolipoprotein A-IV (apo A-IV). This protein is found in cerebrospinal fluid in vivo, and its infusion into the third ventricle of the brain reduces food intake. ...
Chylomicrons have a suppressive effect on food consumption, which is attributed to apolipoprotein A-IV (apo A-IV). This protei …
The Apo(a) gene: structure/function relationships and the possible link with thrombotic atheromatous disease.
Rees A, Bishop A, Morgan R. Rees A, et al. Br Med Bull. 1990 Oct;46(4):873-90. doi: 10.1093/oxfordjournals.bmb.a072444. Br Med Bull. 1990. PMID: 2151625 Review.
The structure of the gene encoding for its unique apo protein, Apo(a) has been determined resulting in possible structure/function relationships which may explain the close association between elevated levels of Lp(a) and atheromatous vascular disease. ...
The structure of the gene encoding for its unique apo protein, Apo(a) has been determined resulting in possible structure/func …
A structural assessment of the apo[a] protein of human lipoprotein[a].
Guevara J Jr, Knapp RD, Honda S, Northup SR, Morrisett JD. Guevara J Jr, et al. Proteins. 1992 Feb;12(2):188-99. doi: 10.1002/prot.340120212. Proteins. 1992. PMID: 1318546
The cDNA-inferred amino acid sequence of apo[a] indicates that apo[a], like plasminogen and some zymogens, is composed of a kringle domain and a serine protease domain. ...In comparing the protease domains of apo[a] and plasmin, apo …
The cDNA-inferred amino acid sequence of apo[a] indicates that apo[a], like plasminogen and some zymogens, is co …
A new Lp(a) assay that is unaffected by apo(a) size polymorphism.
Yamada S, Inoue K, Morishita R, Ogihara T, Kubono K, Kubo N, Abe A, Sakurabayashi I. Yamada S, et al. Clin Chim Acta. 1999 Sep;287(1-2):29-43. doi: 10.1016/s0009-8981(99)00119-9. Clin Chim Acta. 1999. PMID: 10509894
Using serum containing apo(a) with 34 repeats of kringle 4 as the calibrator, a commercial kit using anti-Lp(a) polyclonal antibody (Pab) or anti-apo(a) Mab overestimated the Lp(a) concentration in samples containing apo(a) with more than …
Using serum containing apo(a) with 34 repeats of kringle 4 as the calibrator, a commercial kit using anti-Lp(a) polyclonal ant …
Lipoprotein(a) catabolism: a case of multiple receptors.
McCormick SPA, Schneider WJ. McCormick SPA, et al. Pathology. 2019 Feb;51(2):155-164. doi: 10.1016/j.pathol.2018.11.003. Epub 2018 Dec 27. Pathology. 2019. PMID: 30595508 Review.
Lp(a) is more complex than LDL due to the presence of apolipoprotein(a) [apo(a)], a large glycoprotein sharing extensive homology with plasminogen, which confers some unique properties onto Lp(a) particles. ApoB and apo(a) are essential for the assembl …
Lp(a) is more complex than LDL due to the presence of apolipoprotein(a) [apo(a)], a large glycoprotein sharing extensive homol …
Characterization of apo(a) polymorphism by a modified immunoblotting technique in an Italian population sample.
Geroldi D, Bellotti V, Buscaglia P, Bonetti G, Gazzaruso C, Caprioli A, Fratino P. Geroldi D, et al. Clin Chim Acta. 1993 Nov 30;221(1-2):159-69. doi: 10.1016/0009-8981(93)90030-8. Clin Chim Acta. 1993. PMID: 8149633
Apo(a), the specific lipoprotein(a) (Lp(a)) apolipoprotein, is characterized by different isoforms (from 6 to 11 on SDS-PAGE) encoded by a system of autosomal codominant alleles. ...This simple and reproducible technique could be applied in the genetic screening of …
Apo(a), the specific lipoprotein(a) (Lp(a)) apolipoprotein, is characterized by different isoforms (from 6 to 11 on SDS-PAGE) …
miR-23b-3p and miR-125b-5p downregulate apo(a) expression by targeting Ets1 in HepG2 cells.
Zeng JF, Zeng ZL, Zhang K, Zhao Y, Liu YM, Chen JJ, Tong H, Wei DH, Jiang ZS, Wang Z. Zeng JF, et al. Cell Biol Int. 2018 Mar;42(3):313-323. doi: 10.1002/cbin.10896. Epub 2017 Nov 15. Cell Biol Int. 2018. PMID: 29064597
As a critical positive transacting factor of apo(a) gene, Ets1 has been proven as a target gene of several miRNAs, such as miR-193b, miR-125b-5p, miR-200b, miR-1, and miR-499. In this study, a series of experiments on miRNAs and relative miRNAs inhibitor delivered H …
As a critical positive transacting factor of apo(a) gene, Ets1 has been proven as a target gene of several miRNAs, such as miR …
15,792 results
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