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Year Number of Results
1903 1
1905 1
1912 1
1913 1
1914 1
1915 1
1917 1
1918 1
1919 3
1920 1
1922 1
1923 1
1924 5
1925 1
1926 6
1927 5
1928 6
1929 2
1930 8
1931 2
1932 3
1933 4
1934 6
1935 3
1936 5
1937 7
1938 6
1939 11
1940 2
1941 4
1943 3
1944 2
1945 37
1946 54
1947 90
1948 124
1949 72
1950 84
1951 98
1952 119
1953 149
1954 154
1955 163
1956 139
1957 154
1958 193
1959 200
1960 218
1961 217
1962 206
1963 281
1964 299
1965 354
1966 369
1967 402
1968 626
1969 844
1970 820
1971 888
1972 951
1973 876
1974 779
1975 1118
1976 1333
1977 1210
1978 1114
1979 1120
1980 1252
1981 1396
1982 1512
1983 1800
1984 1952
1985 2340
1986 2519
1987 2685
1988 3026
1989 3196
1990 3362
1991 3398
1992 3569
1993 3629
1994 3908
1995 4034
1996 4023
1997 3896
1998 3899
1999 4097
2000 4430
2001 4544
2002 4503
2003 4708
2004 4765
2005 5135
2006 5385
2007 5287
2008 5532
2009 5302
2010 5593
2011 5696
2012 6000
2013 6177
2014 6211
2015 6042
2016 5893
2017 6050
2018 6094
2019 6314
2020 6627
2021 6650
2022 6465
2023 6337
2024 6897
2025 6390
2026 51

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208,694 results

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Page 1
Enzymatic ester bond formation strategies in fungal macrolide skeletons.
Zhang JM, Yuan GY, Zou Y. Zhang JM, et al. Nat Prod Rep. 2025 Feb 19;42(2):298-323. doi: 10.1039/d4np00050a. Nat Prod Rep. 2025. PMID: 39831437 Review.
In PK-type macrolides, ester bond formation is commonly catalysed by a trans-acting thioesterase (TE) or a cis-acting TE domain during the product release process. ...A comparison of ester bond formation between fungi and bacteria is also discussed. Exploring the bi …
In PK-type macrolides, ester bond formation is commonly catalysed by a trans-acting thioesterase (TE) or a cis-acting TE domain durin …
Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance.
Larsen EM, Johnson RJ. Larsen EM, et al. Drug Dev Res. 2019 Feb;80(1):33-47. doi: 10.1002/ddr.21468. Epub 2018 Oct 10. Drug Dev Res. 2019. PMID: 30302779 Free PMC article. Review.
Ester prodrugs are normally designed to have simple ester groups, as they are expected to be cleaved and reactivated by a wide spectrum of cellular esterases. ...In this review, we highlight the important pathogenic and xenobiotic functions of microbial esterases an …
Ester prodrugs are normally designed to have simple ester groups, as they are expected to be cleaved and reactivated by a wide …
Carboxylic ester hydrolases from hyperthermophiles.
Levisson M, van der Oost J, Kengen SW. Levisson M, et al. Extremophiles. 2009 Jul;13(4):567-81. doi: 10.1007/s00792-009-0260-4. Epub 2009 Jun 21. Extremophiles. 2009. PMID: 19544040 Free PMC article. Review.
Carboxylic ester hydrolyzing enzymes constitute a large group of enzymes that are able to catalyze the hydrolysis, synthesis or transesterification of an ester bond. ...In this review, we aim to give an overview of all characterized carboxylic ester hydrolase …
Carboxylic ester hydrolyzing enzymes constitute a large group of enzymes that are able to catalyze the hydrolysis, synthesis or trans …
[Evaluation of the Oral Absorption of Ester-type Prodrugs].
Ohura K. Ohura K. Yakugaku Zasshi. 2020;140(3):369-376. doi: 10.1248/yakushi.19-00225. Yakugaku Zasshi. 2020. PMID: 32115554 Free article. Review. Japanese.
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respective predominant carboxylesterase (CES) isozymes. In order to provide high blood concentrations of the parent drugs, it is preferable that prod …
The first-pass hydrolysis of oral ester-type prodrugs in the liver and intestine is mediated mainly by hCE1 and hCE2 of the respectiv …
Palladium-Catalyzed Tandem Ester Dance/Decarbonylative Coupling Reactions.
Kubo M, Inayama N, Ota E, Yamaguchi J. Kubo M, et al. Org Lett. 2022 Jun 3;24(21):3855-3860. doi: 10.1021/acs.orglett.2c01432. Epub 2022 May 23. Org Lett. 2022. PMID: 35604648
Notably, dance reactions of halides and pseudohalides offer a unique platform for the divergent synthesis of substituted (hetero)aromatic compounds when combined with transition-metal-catalyzed coupling reactions. Herein, we report a tandem reaction of ester dance and deca …
Notably, dance reactions of halides and pseudohalides offer a unique platform for the divergent synthesis of substituted (hetero)aromatic co …
Performance of Green Surfactants in the Formulation of Heavy-Duty Laundry Liquid Detergents (HDLD) with Special Emphasis on Palm Based Alpha Methyl Ester Sulfonates (alpha-MES).
Low SY, Tan JY, Ban ZH, Siwayanan P. Low SY, et al. J Oleo Sci. 2021 Aug 5;70(8):1027-1037. doi: 10.5650/jos.ess21078. Epub 2021 Jul 9. J Oleo Sci. 2021. PMID: 34248098 Free article. Review.
Liquid detergent has an increasing demand in North America, Western Europe, and Southeast Asia countries owing to its convenience to use and efficiency to clean. Alpha methyl ester sulfonates (alpha-MES), an anionic surfactant derived from palm oil based methyl ester …
Liquid detergent has an increasing demand in North America, Western Europe, and Southeast Asia countries owing to its convenience to use and …
Acridinium Ester Chemiluminescence: Methyl Substitution on the Acridine Moiety.
Nakazono M, Nanbu S, Akita T, Hamase K. Nakazono M, et al. J Oleo Sci. 2021;70(11):1677-1684. doi: 10.5650/jos.ess21186. J Oleo Sci. 2021. PMID: 34732638 Free article.
Methyl groups were introduced on the acridine moiety in chemiluminescent acridinium esters that have electron-withdrawing groups (trifluoromethyl, cyano, nitro, ethoxycarbonyl) at the 4-position on the phenyl ester. The introduction of methyl groups at the 2-, 2,7-, …
Methyl groups were introduced on the acridine moiety in chemiluminescent acridinium esters that have electron-withdrawing groups (tri …
Screening ester-producing yeasts to fortify the brewing of rice-flavor Baijiu for enhanced aromas.
Qu C, Peng L, Fei Y, Liang J, Bai W, Liu G. Qu C, et al. Bioengineered. 2023 Dec;14(1):2255423. doi: 10.1080/21655979.2023.2255423. Bioengineered. 2023. PMID: 37715575 Free PMC article.
To enhance the aromas in Guangdong rice-flavor Baijiu, ester-producing yeast was selected to fortify Baijiu brewing. Among eight kinds of ester-producing yeasts selected, Saccharomyces cerevisiae CM15 (CM15) that showed both the stronger ability to utilize substrate …
To enhance the aromas in Guangdong rice-flavor Baijiu, ester-producing yeast was selected to fortify Baijiu brewing. Among eight kind …
Ester-related volatile compounds reveal the diversity and commonalities of different types of late-ripening peaches.
Li X, Liu C, Wu J, Xiao X, Zhang L, Chen C, Wilson AS, Song F. Li X, et al. J Food Sci. 2024 Mar;89(3):1485-1497. doi: 10.1111/1750-3841.16943. Epub 2024 Feb 5. J Food Sci. 2024. PMID: 38317483
The ester types showed that fatty acid-derived C6 alcohols and methyl-/ethyl- short-chain alcohol were the main ester precursors, which were more likely to be utilized and well selected by alcohol acyltransferases, whereas the preference of acyl donors was not obser …
The ester types showed that fatty acid-derived C6 alcohols and methyl-/ethyl- short-chain alcohol were the main ester precurso …
Cationic Ester Prodrugs of Curcumin with N,N-dimethyl Amino Acid Promoieties Improved Poor Water Solubility and Intestinal Absorption.
Hirano-Kusuda M, Setoguchi S, Koga M, Goto S, Yamada A, Watase D, Nagata-Akaho N, Karube Y, Matsunaga K, Takata J. Hirano-Kusuda M, et al. Pharm Res. 2023 May;40(5):1299-1310. doi: 10.1007/s11095-023-03500-5. Epub 2023 Apr 20. Pharm Res. 2023. PMID: 37081301
METHODS: Two N,N-dimethyl amino acid esters of Cur were synthesized. The hydrolysis profile of the esters was evaluated using rat and human microsomes. ...CONCLUSIONS: The cationic N,N-dimethyl amino acid ester prodrugs of Cur improved the water solubility of …
METHODS: Two N,N-dimethyl amino acid esters of Cur were synthesized. The hydrolysis profile of the esters was evaluated using …
208,694 results
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