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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1969 4
1970 3
1972 2
1974 4
1975 4
1976 7
1977 5
1978 5
1979 2
1980 12
1981 5
1982 7
1983 4
1984 10
1985 8
1986 8
1987 9
1988 6
1989 14
1990 10
1991 12
1992 23
1993 14
1994 14
1995 19
1996 28
1997 21
1998 34
1999 23
2000 38
2001 37
2002 40
2003 53
2004 46
2005 65
2006 59
2007 64
2008 74
2009 58
2010 72
2011 77
2012 75
2013 87
2014 96
2015 119
2016 117
2017 130
2018 176
2019 227
2020 224
2021 285
2022 328
2023 355
2024 473
2025 476
2026 18

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3,793 results

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Page 1
Microneedle-Delivered PDA@Exo for Multifaceted Osteoarthritis Treatment via PI3K-Akt-mTOR Pathway.
Li Z, Lu H, Fan L, Ma X, Duan Z, Zhang Y, Fu Y, Wang S, Guan Y, Yang D, Chen Q, Xu T, Yang Y. Li Z, et al. Adv Sci (Weinh). 2024 Nov;11(42):e2406942. doi: 10.1002/advs.202406942. Epub 2024 Aug 29. Adv Sci (Weinh). 2024. PMID: 39206714 Free PMC article.
PDA@Exo MN shows strong reactive oxygen species (ROS) scavenging abilities and high biocompatibility, fostering osteogenesis and balancing anabolic and catabolic processes in cartilage. ...The PI3K-AKT-mTOR pathway's activation, essential for PDA@Exo's effects, is c …
PDA@Exo MN shows strong reactive oxygen species (ROS) scavenging abilities and high biocompatibility, fostering osteogenesis and bala …
Adipose-derived stem cell exosomes loaded with icariin alleviates rheumatoid arthritis by modulating macrophage polarization in rats.
Yan Q, Liu H, Sun S, Yang Y, Fan D, Yang Y, Zhao Y, Song Z, Chen Y, Zhu R, Zhang Z. Yan Q, et al. J Nanobiotechnology. 2024 Jul 18;22(1):423. doi: 10.1186/s12951-024-02711-1. J Nanobiotechnology. 2024. PMID: 39026367 Free PMC article.
High-performance liquid chromatography analysis confirmed a 92.4 0.008% loading efficiency for ADSCs-EXO-ICA. In vitro studies utilizing cellular immunofluorescence (IF) and flow cytometry demonstrated significant inhibition of M1 macrophage proliferation by ADSCs-EXO …
High-performance liquid chromatography analysis confirmed a 92.4 0.008% loading efficiency for ADSCs-EXO-ICA. In vitro studies utiliz …
Simplified ChIP-exo assays.
Rossi MJ, Lai WKM, Pugh BF. Rossi MJ, et al. Nat Commun. 2018 Jul 20;9(1):2842. doi: 10.1038/s41467-018-05265-7. Nat Commun. 2018. PMID: 30030442 Free PMC article.
In contrast, ChIP-exo has relatively low noise and achieves near-base pair resolution. Consequently, and unlike other genomic assays, ChIP-exo provides structural information on genome-wide binding proteins. Construction of ChIP-exo libraries is technically d …
In contrast, ChIP-exo has relatively low noise and achieves near-base pair resolution. Consequently, and unlike other genomic assays, …
Exosome-mediated delivery of an anti-angiogenic peptide inhibits pathological retinal angiogenesis.
Dong X, Lei Y, Yu Z, Wang T, Liu Y, Han G, Zhang X, Li Y, Song Y, Xu H, Du M, Yin H, Wang X, Yan H. Dong X, et al. Theranostics. 2021 Mar 5;11(11):5107-5126. doi: 10.7150/thno.54755. eCollection 2021. Theranostics. 2021. PMID: 33859737 Free PMC article.
Here, we used this system to load the anti-angiogenic peptide KV11, aiming to establish an EXO-based therapy strategy to suppress neovascularization in the retina. Methods: Using an anchoring peptide, CP05, we linked KV11 to endothelial cell (EC) derived EXOs, yield …
Here, we used this system to load the anti-angiogenic peptide KV11, aiming to establish an EXO-based therapy strategy to suppress neo …
Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway.
Liu W, Yu M, Xie D, Wang L, Ye C, Zhu Q, Liu F, Yang L. Liu W, et al. Stem Cell Res Ther. 2020 Jun 29;11(1):259. doi: 10.1186/s13287-020-01756-x. Stem Cell Res Ther. 2020. PMID: 32600435 Free PMC article.
In this study, we investigated whether melatonin (MT)-pretreated MSCs-derived exosomes (MT-Exo) could exert superior effects on diabetic wound healing, and we attempted to elucidate the underlying mechanism. METHODS: For the evaluation of the anti-infl …
In this study, we investigated whether melatonin (MT)-pretreated MSCs-derived exosomes (MT-Exo) could exert superior ef …
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.
Zhang H, Freitas D, Kim HS, Fabijanic K, Li Z, Chen H, Mark MT, Molina H, Martin AB, Bojmar L, Fang J, Rampersaud S, Hoshino A, Matei I, Kenific CM, Nakajima M, Mutvei AP, Sansone P, Buehring W, Wang H, Jimenez JP, Cohen-Gould L, Paknejad N, Brendel M, Manova-Todorova K, Magalhães A, Ferreira JA, Osório H, Silva AM, Massey A, Cubillos-Ruiz JR, Galletti G, Giannakakou P, Cuervo AM, Blenis J, Schwartz R, Brady MS, Peinado H, Bromberg J, Matsui H, Reis CA, Lyden D. Zhang H, et al. Nat Cell Biol. 2018 Mar;20(3):332-343. doi: 10.1038/s41556-018-0040-4. Epub 2018 Feb 19. Nat Cell Biol. 2018. PMID: 29459780 Free PMC article.
By employing asymmetric flow field-flow fractionation (AF4), we identified two exosome subpopulations (large exosome vesicles, Exo-L, 90-120 nm; small exosome vesicles, Exo-S, 60-80 nm) and discovered an abundant population of non-membranous nanoparticles termed 'ex …
By employing asymmetric flow field-flow fractionation (AF4), we identified two exosome subpopulations (large exosome vesicles, Exo-L, …
Electroacupuncture combined with NSCs-Exo alters the response of hippocampal neurons in a chronic unpredictable mild stress paradigm in ovx rats.
Lyu Q, Shi LQ, Chen HY, Lu M, Liang XC, Ma XD, Zhou X, Ren L. Lyu Q, et al. Life Sci. 2024 Dec 15;359:123235. doi: 10.1016/j.lfs.2024.123235. Epub 2024 Nov 9. Life Sci. 2024. PMID: 39528081 Free article.
In this study, perimenopausal depressive disorder (PDD) rat model were established using a two-step protocol CUMS + OVX. Treatment with EA combined with NSCs-Exo (EA-Exo) significantly improved depression-like behaviors in PDD rats, as indicated by increased sucrose …
In this study, perimenopausal depressive disorder (PDD) rat model were established using a two-step protocol CUMS + OVX. Treatment with EA c …
Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation.
Willis GR, Fernandez-Gonzalez A, Anastas J, Vitali SH, Liu X, Ericsson M, Kwong A, Mitsialis SA, Kourembanas S. Willis GR, et al. Am J Respir Crit Care Med. 2018 Jan 1;197(1):104-116. doi: 10.1164/rccm.201705-0925OC. Am J Respir Crit Care Med. 2018. PMID: 28853608 Free PMC article.
We have reported that the therapeutic capacity of MSCs is comprised in their secretome, and demonstrated that the therapeutic vectors are exosomes produced by MSCs (MSC-exos). OBJECTIVES: To assess efficacy of MSC-exo treatment in a preclinical model of BPD and to investig …
We have reported that the therapeutic capacity of MSCs is comprised in their secretome, and demonstrated that the therapeutic vectors are ex …
Microfluidic-based exosome isolation and highly sensitive aptamer exosome membrane protein detection for lung cancer diagnosis.
Zhao L, Wang H, Fu J, Wu X, Liang XY, Liu XY, Wu X, Cao LL, Xu ZY, Dong M. Zhao L, et al. Biosens Bioelectron. 2022 Oct 15;214:114487. doi: 10.1016/j.bios.2022.114487. Epub 2022 Jun 18. Biosens Bioelectron. 2022. PMID: 35780540 Free article.
Exo-CMDS features in highly qualified yields with optimal exosomal concentration of 5.1 10(9) particles/mL from trace amount of blood samples (<300 muL) in only 8 min, which truly accomplishes the exosome isolation and purification in one-step methods. ...Exo …
Exo-CMDS features in highly qualified yields with optimal exosomal concentration of 5.1 10(9) particles/mL from trace amount of blood …
Exosome-based Ldlr gene therapy for familial hypercholesterolemia in a mouse model.
Li Z, Zhao P, Zhang Y, Wang J, Wang C, Liu Y, Yang G, Yuan L. Li Z, et al. Theranostics. 2021 Jan 1;11(6):2953-2965. doi: 10.7150/thno.49874. eCollection 2021. Theranostics. 2021. PMID: 33456582 Free PMC article.
Development of therapeutic strategies for FH, which causes atherosclerosis and cardiovascular disease, is urgently needed. Methods: Mice with low-density lipoprotein receptor (Ldlr) deletion (Ldlr(-/-) mice) were used as an FH model. Ldlr mRNA was encapsulated into exosome …
Development of therapeutic strategies for FH, which causes atherosclerosis and cardiovascular disease, is urgently needed. Methods: M …
3,793 results