Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Sep;16(3):276-82.

Lead induced oxidative stress: beneficial effects of Kombucha tea

P Dipti  1 , B Yogesh, A K Kain, T Pauline, B Anju, M Sairam, B Singh, S S Mongia, G Ilavazhagan Devendra Kumar, W Selvamurthy
Affiliations
  • PMID: 14631833

Lead induced oxidative stress: beneficial effects of Kombucha tea

P Dipti et al. Biomed Environ Sci. 2003 Sep.

Abstract

Objective: To evaluate the effect of oral administration of Kombucha tea (K-tea) on lead induced oxidative stress.

Methods: Sprague Dawley rats were administered 1 mL of 3.8% lead acetate solution daily alone or in combination with K-tea orally for 45 d, and the antioxidant status and lipid peroxidation were evaluated.

Results: Oral administration of lead acetate to rats enhanced lipid peroxidation and release of creatine phosphokinase and decreased levels of reduced glutathione (GSH) and antioxidant enzymes (superoxide dismutase, SOD and glutathione peroxidase, GPx). Lead treatment did not alter humoral immunity, but inhibited DTH response when compared to the control. Lead administration also increased DNA fragmentation in liver. Oral administration of Kombucha tea to rats exposed to lead decreased lipid peroxidation and DNA damage with a concomitant increase in the reduced glutathione level and GPx activity. Kombucha tea supplementation relieved the lead induced immunosuppression to appreciable levels.

Conclusion: The results suggest that K-tea has potent antioxidant and immunomodulating properties.

PubMed Disclaimer