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225 results

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Odd chain fatty acid metabolism in mice after a high fat diet.
Ampong I, John Ikwuobe O, Brown JEP, Bailey CJ, Gao D, Gutierrez-Merino J, Griffiths HR. Ampong I, et al. Int J Biochem Cell Biol. 2022 Feb;143:106135. doi: 10.1016/j.biocel.2021.106135. Epub 2021 Dec 10. Int J Biochem Cell Biol. 2022. PMID: 34896612 Free PMC article.
Epidemiological studies show that higher circulating levels of odd chain saturated fatty acids (FA: C15:0 and C17:0) are associated with lower risk of metabolic disease. These odd chain saturated fatty acids (OCSFA) are produced by alpha-oxidation in peroxiso …
Epidemiological studies show that higher circulating levels of odd chain saturated fatty acids (FA: C15:0 and C17:0) are assoc …
Association of circulating fatty acids with cardiovascular disease risk: analysis of individual-level data in three large prospective cohorts and updated meta-analysis.
Shi F, Chowdhury R, Sofianopoulou E, Koulman A, Sun L, Steur M, Aleksandrova K, Dahm CC, Schulze MB, van der Schouw YT, Agnoli C, Amiano P, Boer JMA, Bork CS, Cabrera-Castro N, Eichelmann F, Elbaz A, Farràs M, Heath AK, Kaaks R, Katzke V, Keski-Rahkonen P, Masala G, Moreno-Iribas C, Panico S, Papier K, Petrova D, Quirós JR, Ricceri F, Severi G, Tjønneland A, Tong TYN, Tumino R, Wareham NJ, Weiderpass E, Di Angelantonio E, Forouhi NG, Danesh J, Butterworth AS, Kaptoge S. Shi F, et al. Eur J Prev Cardiol. 2025 Feb 18;32(3):233-246. doi: 10.1093/eurjpc/zwae315. Eur J Prev Cardiol. 2025. PMID: 39365172 Free PMC article.
Hazard ratio (HR) per 1-standard deviation (SD) higher FA concentrations was estimated using Cox regression models and pooled by random-effects meta-analysis. ...In the combined analysis, total n-3 polyunsaturated FA (PUFA) [0.91 (0.85-0.97)], including docosahexaen …
Hazard ratio (HR) per 1-standard deviation (SD) higher FA concentrations was estimated using Cox regression models and pooled by rand …
Role of 2-hydroxy acyl-CoA lyase HACL2 in odd-chain fatty acid production via alpha-oxidation in vivo.
Mori K, Naganuma T, Kihara A. Mori K, et al. Mol Biol Cell. 2023 Aug 1;34(9):ar85. doi: 10.1091/mbc.E23-02-0042. Epub 2023 Jun 7. Mol Biol Cell. 2023. PMID: 37285239 Free PMC article.
We observed fewer odd-chain lipids and more 2-OH lipids in many tissues of Hacl2 KO mice than in wild-type mice, and of these differences the reductions were most prominent for odd-chain monohexosylceramides in the brain and ceramides in the stomach. These results i …
We observed fewer odd-chain lipids and more 2-OH lipids in many tissues of Hacl2 KO mice than in wild-type mice, and of these differe …
Comparison of Milk Odd- and Branched-Chain Fatty Acids among Human, Dairy Species and Artificial Substitutes.
Carta S, Correddu F, Battacone G, Pulina G, Nudda A. Carta S, et al. Foods. 2022 Dec 19;11(24):4118. doi: 10.3390/foods11244118. Foods. 2022. PMID: 36553860 Free PMC article.
Among ruminants, sheep milk had the highest OBCFA (4.5 g/100 g of total FAME), whereases the lowest values were found in formula milk (0.18 g/100 g of total FAME). Regarding individual linear odd-chain FA (linear-OCFA), C11:0 was found higher in donkey milk than oth …
Among ruminants, sheep milk had the highest OBCFA (4.5 g/100 g of total FAME), whereases the lowest values were found in formula milk (0.18 …
Phylogenetic Aspects of Higher Plant Lipid Fatty Acid Profile.
Voronkov A, Ivanova T. Voronkov A, et al. Int J Mol Sci. 2025 Sep 26;26(19):9424. doi: 10.3390/ijms26199424. Int J Mol Sci. 2025. PMID: 41096711 Free PMC article. Review.
They participate in maintaining homeostasis by controlling membrane permeability. Changes in the FA composition of lipid bilayers can modulate the transition of the membrane from a liquid crystalline to a gel-like state. Thus, knowledge of a plant's FA profile can a …
They participate in maintaining homeostasis by controlling membrane permeability. Changes in the FA composition of lipid bilayers can …
Counting modes of acyl-lipid desaturases.
Starikov AY, Sidorov RA, Los DA. Starikov AY, et al. Funct Plant Biol. 2025 Apr;52:FP24338. doi: 10.1071/FP24338. Funct Plant Biol. 2025. PMID: 40184375 Review.
The regiospecificity of soluble Acyl-Carrier-Protein (ACP) delta9-FADs was determined relative to the carboxyl end of the FA. Similar regiospecificity was suggested for acyl-lipid and acyl-CoA FADs delta9-FADs. It was previously thought that acyl-lipid delta12-FADs (also k …
The regiospecificity of soluble Acyl-Carrier-Protein (ACP) delta9-FADs was determined relative to the carboxyl end of the FA. Similar …
Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial.
Sowah SA, Koulman A, Sharp SJ, Imamura F, Khaw KT, Forouhi NG. Sowah SA, et al. J Lipid Res. 2024 Dec;65(12):100681. doi: 10.1016/j.jlr.2024.100681. Epub 2024 Oct 28. J Lipid Res. 2024. PMID: 39490924 Free PMC article. Clinical Trial.
We aimed to evaluate the effects of coconut oil, olive oil and butter on circulating FA concentrations, and examine the associations between changes in plasma FAs and changes in metabolic markers. ...The interventions of equal amounts of different food FA sources al …
We aimed to evaluate the effects of coconut oil, olive oil and butter on circulating FA concentrations, and examine the associations …
Odd-chain polyunsaturated fatty acids in thraustochytrids.
Chang KJ, Mansour MP, Dunstan GA, Blackburn SI, Koutoulis A, Nichols PD. Chang KJ, et al. Phytochemistry. 2011 Aug;72(11-12):1460-5. doi: 10.1016/j.phytochem.2011.04.001. Epub 2011 May 3. Phytochemistry. 2011. PMID: 21546043
A series of unusual odd-chain fatty acids (OC-FA) were identified in two thraustochytrid strains, TC 01 and TC 04, isolated from waters off the south east coast of Tasmania, Australia. ...High proportions of the saturated OC-FA 15:0 (7.1% in TC 01) and 17:0 ( …
A series of unusual odd-chain fatty acids (OC-FA) were identified in two thraustochytrid strains, TC 01 and TC 04, isolated fr …
Biotransformation of volatile fatty acids by oleaginous and non-oleaginous yeast species.
Kolouchová I, Schreiberová O, Sigler K, Masák J, Řezanka T. Kolouchová I, et al. FEMS Yeast Res. 2015 Nov;15(7):fov076. doi: 10.1093/femsyr/fov076. Epub 2015 Aug 30. FEMS Yeast Res. 2015. PMID: 26323601
The lipid composition was comparable to plant-derived oils and therefore might be exploitable in biodiesel production; nearly all species, when cultured on propionate, showed a high content of the desirable odd-chain unsaturated FA, especially 17:1 acid. This study …
The lipid composition was comparable to plant-derived oils and therefore might be exploitable in biodiesel production; nearly all species, w …
Milk saturated fatty acids, odd- and branched-chain fatty acids, and isomers of C18:1, C18:2, and C18:3n-3 according to their duodenal flows in dairy cows: A meta-analysis approach.
Prado LA, Schmidely P, Nozière P, Ferlay A. Prado LA, et al. J Dairy Sci. 2019 Apr;102(4):3053-3070. doi: 10.3168/jds.2018-15194. Epub 2019 Feb 7. J Dairy Sci. 2019. PMID: 30738686 Free article.
We sought to establish predictive response models of milk fatty acid (FA) yields or concentrations from their respective duodenal flow, rumen digestive parameters, or diet characteristics in dairy cows, with a special focus on cis and trans isomers of C18:1, C18:2, odd …
We sought to establish predictive response models of milk fatty acid (FA) yields or concentrations from their respective duodenal flo …
225 results