otomo a - Search Results

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Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.

Fujimori K, Ishikawa M, Otomo A, Atsuta N, Nakamura R, Akiyama T, Hadano S, Aoki M, Saya H, Sobue G, Okano H. Fujimori K, et al. Among authors: otomo a. Nat Med. 2018 Oct;24(10):1579-1589. doi: 10.1038/s41591-018-0140-5. Epub 2018 Aug 20. Nat Med. 2018. PMID: 30127392

Na⁺-V-ATPase inhibitor curbs VRE growth and unveils Na⁺ pathway structure.

Suzuki K, Goto Y, Otomo A, Shimizu K, Abe S, Moriyama K, Yasuda S, Hashimoto Y, Kurushima J, Mikuriya S, Imai FL, Adachi N, Kawasaki M, Sato Y, Ogasawara S, Iwata S, Senda T, Ikeguchi M, Tomita H, Iino R, Moriya T, Murata T. Suzuki K, et al. Among authors: otomo a. Nat Struct Mol Biol. 2025 Mar;32(3):450-458. doi: 10.1038/s41594-024-01419-y. Epub 2024 Nov 21. Nat Struct Mol Biol. 2025. PMID: 39572733

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

Suzuki-Utsunomiya K, Hadano S, Otomo A, Kunita R, Mizumura H, Osuga H, Ikeda JE. Suzuki-Utsunomiya K, et al. Among authors: otomo a. Biochem Biophys Res Commun. 2007 Mar 9;354(2):491-7. doi: 10.1016/j.bbrc.2006.12.229. Epub 2007 Jan 11. Biochem Biophys Res Commun. 2007. PMID: 17239822

Investigation of early axonal phenotypes in an iPSC-derived ALS cellular model using a microfluidic device.

Otomo A, Nishijima K, Murakami Y, Ishikawa M, Yudahira H, Shimakura K, Okano H, Aoki M, Kimura H, Hadano S. Otomo A, et al. Front Cell Neurosci. 2025 Jul 24;19:1590732. doi: 10.3389/fncel.2025.1590732. eCollection 2025. Front Cell Neurosci. 2025. PMID: 40777082 Free PMC article.

SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron.

Mitsui S, Otomo A, Sato K, Ishiyama M, Shimakura K, Okada-Yamaguchi C, Warabi E, Yanagawa T, Aoki M, Shang HF, Hadano S. Mitsui S, et al. Among authors: otomo a. Neurochem Int. 2022 Sep;158:105364. doi: 10.1016/j.neuint.2022.105364. Epub 2022 May 28. Neurochem Int. 2022. PMID: 35640762 Free article.

Visualizing Single V-ATPase Rotation Using Janus Nanoparticles.

Otomo A, Wiemann J, Bhattacharyya S, Yamamoto M, Yu Y, Iino R. Otomo A, et al. Nano Lett. 2024 Dec 11;24(49):15638-15644. doi: 10.1021/acs.nanolett.4c04109. Epub 2024 Nov 22. Nano Lett. 2024. PMID: 39573818 Free PMC article.

Protein dynamics of a light-driven Na⁺ pump rhodopsin probed using a tryptophan residue near the retinal chromophore.

Otomo A, Mizuno M, Inoue K, Kandori H, Mizutani Y. Otomo A, et al. Biophys Physicobiol. 2023 Feb 25;20(Supplemental):e201016. doi: 10.2142/biophysico.bppb-v20.s016. eCollection 2023 Mar 21. Biophys Physicobiol. 2023. PMID: 38362331 Free PMC article.

Rational engineering of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins.

Harashima T, Otomo A, Iino R. Harashima T, et al. Among authors: otomo a. Nat Commun. 2025 Jan 16;16(1):729. doi: 10.1038/s41467-025-56036-0. Nat Commun. 2025. PMID: 39820287 Free PMC article.

A Study of the Dynamics of the Heme Pocket and C-helix in CooA upon CO Dissociation Using Time-Resolved Visible and UV Resonance Raman Spectroscopy.

Otomo A, Ishikawa H, Mizuno M, Kimura T, Kubo M, Shiro Y, Aono S, Mizutani Y. Otomo A, et al. J Phys Chem B. 2016 Aug 18;120(32):7836-43. doi: 10.1021/acs.jpcb.6b05634. Epub 2016 Aug 5. J Phys Chem B. 2016. PMID: 27457181

Light-Emitting Electrochemical Cells Based on Nanogap Electrodes.

Yonemoto R, Ueda R, Otomo A, Noguchi Y. Yonemoto R, et al. Among authors: otomo a. Nano Lett. 2023 Aug 23;23(16):7493-7499. doi: 10.1021/acs.nanolett.3c02001. Epub 2023 Aug 14. Nano Lett. 2023. PMID: 37579029

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