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Year Number of Results
1898 1
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1929 1
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1959 1
1960 1
1964 1
1965 1
1966 2
1967 3
1968 7
1969 10
1970 9
1971 7
1972 8
1973 7
1974 10
1975 48
1976 58
1977 34
1978 25
1979 29
1980 57
1981 49
1982 44
1983 42
1984 50
1985 69
1986 53
1987 56
1988 71
1989 73
1990 76
1991 61
1992 67
1993 101
1994 66
1995 88
1996 93
1997 103
1998 93
1999 114
2000 135
2001 133
2002 142
2003 169
2004 167
2005 208
2006 194
2007 215
2008 216
2009 259
2010 245
2011 277
2012 325
2013 305
2014 410
2015 452
2016 477
2017 554
2018 617
2019 698
2020 722
2021 901
2022 902
2023 892
2024 948
2025 797
2026 2

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11,929 results

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Page 1
Dynamic split G-quadruplex programmed reversible nanodevice.
Yu Y , Zhou Y , Zhu M , Su G , Deng H , Chen W , Peng H . Yu Y , et al. Chem Commun (Camb). 2019 Jan 2;55(3):389-392. doi: 10.1039/c8cc08744j. Chem Commun (Camb). 2019. PMID: 30540300
We propose a dynamic nanodevice based on a split G-quadruplex (G4). By splitting it apart, we can successfully decouple the G-tetrad formation from external stimuli, greatly expanding the stimulus for G4 based devices. ...
We propose a dynamic nanodevice based on a split G-quadruplex (G4). By splitting it apart, we can successfully decouple …
Toward a Rational Approach to Design Split G-Quadruplex Probes.
Connelly RP, Verduzco C, Farnell S, Yishay T, Gerasimova YV. Connelly RP, et al. ACS Chem Biol. 2019 Dec 20;14(12):2701-2712. doi: 10.1021/acschembio.9b00634. Epub 2019 Oct 22. ACS Chem Biol. 2019. PMID: 31599573 Free PMC article.
Systematic efforts in probe optimization resulted in their improved binding affinity, turn-on ratios, and ability to discriminate single nucleotide substitutions (SNSs). The use of split (or multicomponent) probes is a promising strategy to improve probe selectivity and en …
Systematic efforts in probe optimization resulted in their improved binding affinity, turn-on ratios, and ability to discriminate single nuc …
Identification and Classification of Functional Split G-Quadruplexes Using Machine Learning-Guided Activity Screening.
Das P, Das A, Debnath M. Das P, et al. ACS Appl Bio Mater. 2025 Jun 16;8(6):4844-4854. doi: 10.1021/acsabm.5c00215. Epub 2025 May 25. ACS Appl Bio Mater. 2025. PMID: 40415306
Split G-quadruplexes are considered excellent tools for biosensing and diagnostics, but splitting G-quadruplexes may often lead to a loss of function, limiting their effectiveness. This study aims to identify and classify functional split G …
Split G-quadruplexes are considered excellent tools for biosensing and diagnostics, but splitting G-quadruplexes …
Chiral Split Magnon in Altermagnetic MnTe.
Liu Z, Ozeki M, Asai S, Itoh S, Masuda T. Liu Z, et al. Phys Rev Lett. 2024 Oct 11;133(15):156702. doi: 10.1103/PhysRevLett.133.156702. Phys Rev Lett. 2024. PMID: 39454157
Altermagnetism is a newly recognized magnetic class named after the alternating spin polarizations in both real and reciprocal spaces. Like the spin splitting of electronic bands, the magnon bands in altermagnets are predicted to exhibit alternating chiral splitting …
Altermagnetism is a newly recognized magnetic class named after the alternating spin polarizations in both real and reciprocal spaces. Like …
Split-Protein Therapeutic Platforms: Identifying Binder Pairs.
Nervig CS, Gustat JR, Owen SC. Nervig CS, et al. Methods Mol Biol. 2024;2720:75-84. doi: 10.1007/978-1-0716-3469-1_5. Methods Mol Biol. 2024. PMID: 37775658
A promising approach to overcome such toxicity is to create conditionally active constructs by splitting the therapeutic protein into two, or more, inactive fragments and by fusing these fragments to binders (e.g., antibodies) that target distinct epitopes on a cell …
A promising approach to overcome such toxicity is to create conditionally active constructs by splitting the therapeutic protein into …
Split nerve grafting.
Eberhard D, Millesi H. Eberhard D, et al. J Reconstr Microsurg. 1996 Feb;12(2):71-6. doi: 10.1055/s-2007-1006456. J Reconstr Microsurg. 1996. PMID: 8656403
Twenty-five patients with severe brachial plexus lesions (having a rather poor prognosis in general), were subjected to a variety of split nerve graft procedures, with 22 achieving useful functional recovery. Thirty-eight nerves were reconstructed, with 32 of them achievin …
Twenty-five patients with severe brachial plexus lesions (having a rather poor prognosis in general), were subjected to a variety of spli …
A split cytosine deaminase architecture enables robust inducible base editing.
Long J, Liu N, Tang W, Xie L, Qin F, Zhou L, Tao R, Wang Y, Hu Y, Jiao Y, Li L, Jiang L, Qu J, Chen Q, Yao S. Long J, et al. FASEB J. 2021 Dec;35(12):e22045. doi: 10.1096/fj.202100123R. FASEB J. 2021. PMID: 34797942
In the guidance of structural information, we designed four split-human APOBEC3A (A3A) -BE3 base editors in which these A3A deaminase enzymes were split at sites that were opposite to the protein-nucleotide interface. ...Among these split editors, splicing at …
In the guidance of structural information, we designed four split-human APOBEC3A (A3A) -BE3 base editors in which these A3A deaminase …
Nonperturbative Matrix Mechanics Approach to Spin-Split Landau Levels and the g Factor in Spin-Orbit Coupled Solids.
Izaki Y, Fuseya Y. Izaki Y, et al. Phys Rev Lett. 2019 Oct 11;123(15):156403. doi: 10.1103/PhysRevLett.123.156403. Phys Rev Lett. 2019. PMID: 31702292
We propose a fully quantum approach to nonperturbatively calculate the spin-split Landau levels and g factor of various spin-orbit coupled solids based on the k.p theory in the matrix mechanics representation. ...Contrary to popular belief, we show that the spin- …
We propose a fully quantum approach to nonperturbatively calculate the spin-split Landau levels and g factor of various spin-o …
Unifying Splitting.
Ebner G, Blanchette J, Tourret S. Ebner G, et al. J Autom Reason. 2023;67(2):16. doi: 10.1007/s10817-023-09660-8. Epub 2023 Apr 28. J Autom Reason. 2023. PMID: 37131534 Free PMC article.
And how does it relate to other splitting architectures? To answer these questions, we present a unifying framework that extends a saturation calculus (e.g., superposition) with splitting and that embeds the result in a prover guided by a SAT solver. ...Vario …
And how does it relate to other splitting architectures? To answer these questions, we present a unifying framework that extends a sa …
Three-dimensional splitting microfluidics.
Chen Y, Gao W, Zhang C, Zhao Y. Chen Y, et al. Lab Chip. 2016 Apr 21;16(8):1332-9. doi: 10.1039/c6lc00186f. Lab Chip. 2016. PMID: 27030216
Microfluidic systems with splitting structures are excellent for increasing emulsion production. However, traditional two-dimensional (2D) lithographic systems require complex modification of the microchannel surfaces and achieve only 2D splitting of the droplets. . …
Microfluidic systems with splitting structures are excellent for increasing emulsion production. However, traditional two-dimensional …
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