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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1986 2
1987 2
1988 15
1989 41
1990 60
1991 77
1992 71
1993 77
1994 50
1995 59
1996 45
1997 50
1998 52
1999 50
2000 64
2001 68
2002 78
2003 89
2004 114
2005 107
2006 128
2007 132
2008 131
2009 103
2010 119
2011 138
2012 143
2013 124
2014 110
2015 126
2016 126
2017 115
2018 101
2019 103
2020 79
2021 72
2022 39
2023 22
2024 87
2025 84
2026 4

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2,923 results

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Page 1
Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke.
Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, Yan B, Bush SJ, Dewey HM, Thijs V, Scroop R, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Ang T, Miteff F, Levi CR, Rodrigues E, Zhao H, Salvaris P, Garcia-Esperon C, Bailey P, Rice H, de Villiers L, Brown H, Redmond K, Leggett D, Fink JN, Collecutt W, Wong AA, Muller C, Coulthard A, Mitchell K, Clouston J, Mahady K, Field D, Ma H, Phan TG, Chong W, Chandra RV, Slater LA, Krause M, Harrington TJ, Faulder KC, Steinfort BS, Bladin CF, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM; EXTEND-IA TNK Investigators. Campbell BCV, et al. N Engl J Med. 2018 Apr 26;378(17):1573-1582. doi: 10.1056/NEJMoa1716405. N Engl J Med. 2018. PMID: 29694815 Free article. Clinical Trial.
Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial.
Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray TA, Collins G, Zhang L, Kalra R, Kosmopoulos M, John R, Shaffer A, Frascone RJ, Wesley K, Conterato M, Biros M, Tolar J, Aufderheide TP. Yannopoulos D, et al. Lancet. 2020 Dec 5;396(10265):1807-1816. doi: 10.1016/S0140-6736(20)32338-2. Epub 2020 Nov 13. Lancet. 2020. PMID: 33197396 Free PMC article. Clinical Trial.
Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization.
Binder NF, El Amki M, Glück C, Middleham W, Reuss AM, Bertolo A, Thurner P, Deffieux T, Lambride C, Epp R, Handelsmann HL, Baumgartner P, Orset C, Bethge P, Kulcsar Z, Aguzzi A, Tanter M, Schmid F, Vivien D, Wyss MT, Luft A, Weller M, Weber B, Wegener S. Binder NF, et al. Neuron. 2024 May 1;112(9):1456-1472.e6. doi: 10.1016/j.neuron.2024.01.031. Epub 2024 Feb 26. Neuron. 2024. PMID: 38412858 Free article.
Discussion.
Tweddell JS. Tweddell JS. J Thorac Cardiovasc Surg. 2022 Jan;163(1):e57-e58. doi: 10.1016/j.jtcvs.2020.12.017. Epub 2021 Jan 21. J Thorac Cardiovasc Surg. 2022. PMID: 33485655 Free article. No abstract available.
Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke: The POST-UK Randomized Clinical Trial.
Liu C, Guo C, Li F, Yu N, Huang J, Peng Z, Kong W, Song J, Liu X, Fan S, Yue C, Chen B, Zheng C, Yuan X, Sheng J, Wu Y, Sun B, Zhao Z, Zhu M, Han L, Shi Q, Xia Z, Shang X, Li F, Li R, Yue F, Jiang S, Song D, Song M, Shan Y, Ding C, Yao L, Yang Y, Chen J, He W, Pan F, Zhang W, Cai T, Han S, Li W, Li G, Gong C, Huang L, Huang C, Wang D, Kaesmacher J, Nguyen TN, Nogueira RG, Saver JL, Zi W, Chen Y, Yang Q; POST-UK investigators. Liu C, et al. JAMA. 2025 Feb 18;333(7):589-598. doi: 10.1001/jama.2024.23480. JAMA. 2025. PMID: 39804674 Free PMC article. Clinical Trial.
Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke: The POST-TNK Randomized Clinical Trial.
Huang J, Yang J, Liu C, Li L, Yang D, Guo C, Zeng G, Song J, Ma J, Xu X, Shi X, Yang S, Sun W, Wang Z, Tang Y, Jiang M, Wang L, Cheng X, Luo J, Zhou P, Fang X, Cheng G, Ruan Z, Li J, Liu J, Lei B, Tian Y, Tan X, Yuan G, Wang J, Huang X, Deng S, Jin Z, Zou X, Zhang J, Cheng D, Luo X, Liao J, Miao J, Li Z, Sun Y, Jiang G, Kong D, Jiang S, Wang Z, Wang D, Kaesmacher J, Nguyen TN, Nogueira RG, Saver JL, Chen Y, Zi W; POST-TNK Investigators. Huang J, et al. JAMA. 2025 Feb 18;333(7):579-588. doi: 10.1001/jama.2024.23466. JAMA. 2025. PMID: 39804681 Free PMC article. Clinical Trial.
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke.
Yang P, Zhang Y, Zhang L, Zhang Y, Treurniet KM, Chen W, Peng Y, Han H, Wang J, Wang S, Yin C, Liu S, Wang P, Fang Q, Shi H, Yang J, Wen C, Li C, Jiang C, Sun J, Yue X, Lou M, Zhang M, Shu H, Sun D, Liang H, Li T, Guo F, Ke K, Yuan H, Wang G, Yang W, Shi H, Li T, Li Z, Xing P, Zhang P, Zhou Y, Wang H, Xu Y, Huang Q, Wu T, Zhao R, Li Q, Fang Y, Wang L, Lu J, Li Y, Fu J, Zhong X, Wang Y, Wang L, Goyal M, Dippel DWJ, Hong B, Deng B, Roos YBWEM, Majoie CBLM, Liu J; DIRECT-MT Investigators. Yang P, et al. N Engl J Med. 2020 May 21;382(21):1981-1993. doi: 10.1056/NEJMoa2001123. Epub 2020 May 6. N Engl J Med. 2020. PMID: 32374959 Clinical Trial.
Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial.
Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, Yan B, Bush SJ, Thijs V, Scroop R, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Zhao H, Alemseged F, Ng F, Bailey P, Rice H, de Villiers L, Dewey HM, Choi PMC, Brown H, Redmond K, Leggett D, Fink JN, Collecutt W, Kraemer T, Krause M, Cordato D, Field D, Ma H, O'Brien B, Clissold B, Miteff F, Clissold A, Cloud GC, Bolitho LE, Bonavia L, Bhattacharya A, Wright A, Mamun A, O'Rourke F, Worthington J, Wong AA, Levi CR, Bladin CF, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM; EXTEND-IA TNK Part 2 investigators. Campbell BCV, et al. JAMA. 2020 Apr 7;323(13):1257-1265. doi: 10.1001/jama.2020.1511. JAMA. 2020. PMID: 32078683 Free PMC article. Clinical Trial.
2,923 results