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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 15
2008 54
2009 71
2010 94
2011 150
2012 225
2013 272
2014 372
2015 386
2016 424
2017 389
2018 491
2019 486
2020 424
2021 411
2022 78
2023 34
2024 158
2025 308

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4,290 results

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Page 1
Small-molecule discovery through DNA-encoded libraries.
Peterson AA, Liu DR. Peterson AA, et al. Nat Rev Drug Discov. 2023 Sep;22(9):699-722. doi: 10.1038/s41573-023-00713-6. Epub 2023 Jun 16. Nat Rev Drug Discov. 2023. PMID: 37328653 Free PMC article. Review.
Targeting STING with covalent small-molecule inhibitors.
Haag SM, Gulen MF, Reymond L, Gibelin A, Abrami L, Decout A, Heymann M, van der Goot FG, Turcatti G, Behrendt R, Ablasser A. Haag SM, et al. Nature. 2018 Jul;559(7713):269-273. doi: 10.1038/s41586-018-0287-8. Epub 2018 Jul 4. Nature. 2018. PMID: 29973723
Small-Molecule Modulators of Toll-like Receptors.
Wang Y, Zhang S, Li H, Wang H, Zhang T, Hutchinson MR, Yin H, Wang X. Wang Y, et al. Acc Chem Res. 2020 May 19;53(5):1046-1055. doi: 10.1021/acs.accounts.9b00631. Epub 2020 Apr 1. Acc Chem Res. 2020. PMID: 32233400 Review.
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Fan S, Yue L, Wan W, Zhang Y, Zhang B, Otomo C, Li Q, Lin T, Hu J, Xu P, Zhu M, Tao H, Chen Z, Li L, Ding H, Yao Z, Lu J, Wen Y, Zhang N, Tan M, Chen K, Xie Y, Otomo T, Zhou B, Jiang H, Dang Y, Luo C. Fan S, et al. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26105-26114. doi: 10.1002/anie.202109464. Epub 2021 Nov 5. Angew Chem Int Ed Engl. 2021. PMID: 34590387 Free PMC article.
Correlating chemical sensitivity and basal gene expression reveals mechanism of action.
Rees MG, Seashore-Ludlow B, Cheah JH, Adams DJ, Price EV, Gill S, Javaid S, Coletti ME, Jones VL, Bodycombe NE, Soule CK, Alexander B, Li A, Montgomery P, Kotz JD, Hon CS, Munoz B, Liefeld T, Dančík V, Haber DA, Clish CB, Bittker JA, Palmer M, Wagner BK, Clemons PA, Shamji AF, Schreiber SL. Rees MG, et al. Nat Chem Biol. 2016 Feb;12(2):109-16. doi: 10.1038/nchembio.1986. Epub 2015 Dec 14. Nat Chem Biol. 2016. PMID: 26656090 Free PMC article.
4,290 results