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. 2000 Apr 25;1491(1-3):355-63.
doi: 10.1016/s0167-4781(00)00047-6.

Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths

J Lee  1 , Y Hahn, J H Yun, K Mita, J H Chung
Affiliations

Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths

J Lee et al. Biochim Biophys Acta. .

Abstract

We characterized evolutionarily conserved J domain containing protein (JDP) genes from human, Bombyx mori, and Manduca sexta. Each of the JDP proteins contains a J domain at its N-terminus and a highly conserved C-terminal domain. Southern blot analysis revealed that the human JDP1 gene is present as a single copy in the human genome. Expression was higher in brain, heart, and testis than in kidney or stomach. Human JDP1 was mapped in silico to chromosome 10q21.1, which exhibits a conserved synteny with the central region of mouse chromosome 10. Drosophila jdp is located at 99F4-99F11 on the right arm of the third chromosome.

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