Retrospective analysis of 515 cases of Crohn's disease hospitalization in China: nationwide study from 1990 to 2003

Abstract

Background: The purpose of the present paper was to investigate the status of Crohn's disease hospitalization in China.

Methods: Medical records of hospitalized Crohn's disease came from 22 medical centers across China during 1990-2003 and were retrospectively reviewed. Every incident case was recorded in detail on a regular comprehensive datum form by investigators in person. Clinical manifestations, examinations and therapeutic status were analyzed.

Results: A total of 515 cases of Crohn's disease were found. The ratio of patients with Crohn's disease to total hospitalized patients has increased steadily year by year. Endoscopy was performed in 348 patients (67.57%). Barium meal or enema was performed in 221 patients (42.91%). Histological examination (endoscopical or surgical biopsy) was performed in 340 patients (66.02%). Reasonable treatment strategies were used for 435 patients (84.47%). The evaluation of quality of life for 54/303 patients (17.82%) was poor.

Conclusions: This retrospective, hospital-based study shows that the number of patients with Crohn's disease in China has steadily increased over a period of 14 years. Further population-based epidemiological studies specifically focusing on risk factors are needed. The diagnosis of Crohn's disease and therapeutic strategy require improvement.