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Page 1
Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v.
Matuskova H, Marasek P, Mazhara V, Simonova E, Kosinova L, Danek P, Danova K, Sajnerova K, Malatova I, Hrabankova K, Greco D, Martinec O, Fabisik M, Podzimkova N, Hladikova K, Behalova K, Antosova Z, Sirova M, Mikyskova R, Reinis M, Kovar M, Béchard D, Moebius U, Palova Jelinkova L, Spisek R, Steegmaier M, Adkins I. Matuskova H, et al. Among authors: adkins i. J Immunother Cancer. 2025 Apr 17;13(4):e010736. doi: 10.1136/jitc-2024-010736. J Immunother Cancer. 2025. PMID: 40250867 Free PMC article.
Radiotherapy in Combination With Cytokine Treatment.
Palata O, Hradilova Podzimkova N, Nedvedova E, Umprecht A, Sadilkova L, Palova Jelinkova L, Spisek R, Adkins I. Palata O, et al. Among authors: adkins i. Front Oncol. 2019 May 22;9:367. doi: 10.3389/fonc.2019.00367. eCollection 2019. Front Oncol. 2019. PMID: 31179236 Free PMC article. Review.
Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers.
Champiat S, Garralda E, Galvao V, Cassier PA, Gomez-Roca C, Korakis I, Grell P, Naing A, LoRusso P, Mikyskova R, Podzimkova N, Reinis M, Ouali K, Schoenenberger A, Kiemle-Kallee J, Tillmanns S, Sachse R, Moebius U, Spisek R, Bechard D, Jelinkova LP, Adkins I, Marabelle A. Champiat S, et al. Among authors: adkins i. Cell Rep Med. 2025 Feb 18;6(2):101967. doi: 10.1016/j.xcrm.2025.101967. Epub 2025 Feb 10. Cell Rep Med. 2025. PMID: 39933529 Free PMC article. Clinical Trial.
Bacteria and their toxins tamed for immunotherapy.
Adkins I, Holubova J, Kosova M, Sadilkova L. Adkins I, et al. Curr Pharm Biotechnol. 2012 Jun;13(8):1446-73. doi: 10.2174/138920112800784835. Curr Pharm Biotechnol. 2012. PMID: 22339216 Review.
RTX proteins: a highly diverse family secreted by a common mechanism.
Linhartová I, Bumba L, Mašín J, Basler M, Osička R, Kamanová J, Procházková K, Adkins I, Hejnová-Holubová J, Sadílková L, Morová J, Sebo P. Linhartová I, et al. Among authors: adkins i. FEMS Microbiol Rev. 2010 Nov;34(6):1076-112. doi: 10.1111/j.1574-6976.2010.00231.x. FEMS Microbiol Rev. 2010. PMID: 20528947 Free PMC article. Review.
30 results