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Page 1
Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells.
Takata H, Kakazu JC, Mitchell JL, Kroon E, Colby DJ, Sacdalan C, Bai H, Ehrenberg PK, Geretz A, Buranapraditkun S, Pinyakorn S, Intasan J, Tipsuk S, Suttichom D, Prueksakaew P, Chalermchai T, Chomchey N, Phanuphak N, de Souza M, Michael NL, Robb ML, Haddad EK, Crowell TA, Vasan S, Valcour VG, Douek DC, Thomas R, Rolland M, Chomont N, Ananworanich J, Trautmann L; RV254/SEARCH010, RV304/ SEARCH013, and SEARCH011 study groups. Takata H, et al. EBioMedicine. 2022 Oct;84:104253. doi: 10.1016/j.ebiom.2022.104253. Epub 2022 Sep 8. EBioMedicine. 2022. PMID: 36088683 Free PMC article.
Improved HIV-1 RNA detection using whole blood versus plasma in antiretroviral-treated individuals.
Avelino-Silva VI, Stone M, Montalvo L, Di Germanio C, Bakkour S, Lanteri MC, Grebe E, Custer B, Deng X, Buccheri R, Harrington K, Kleinman SH, Vasan S, Phanuphak N, Sacdalan C, Akapirat S, de Souza M, Kallás EG, de Oliveira Garcia Mateos S, Sabino EC, Norris PJ, Busch MP; NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P). Avelino-Silva VI, et al. Among authors: akapirat s. J Clin Microbiol. 2025 Jul 9;63(7):e0190424. doi: 10.1128/jcm.01904-24. Epub 2025 Jun 4. J Clin Microbiol. 2025. PMID: 40464602 Free PMC article.
Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition.
Schuetz A, Corley MJ, Sacdalan C, Phuang-Ngern Y, Nakpor T, Wansom T, Ehrenberg PK, Sriplienchan S, Thomas R, Ratnaratorn N, Sukhumvittaya S, Tragonlugsana N, Slike BM, Akapirat S, Pinyakorn S, Rerknimitr R, Pang AP, Kroon E, Teeratakulpisan N, Krebs SJ, Phanuphak N, Ndhlovu LC, Vasan S; RV304/SEARCH013 Study Team. Schuetz A, et al. Among authors: akapirat s. JCI Insight. 2023 Aug 22;8(16):e169272. doi: 10.1172/jci.insight.169272. JCI Insight. 2023. PMID: 37432754 Free PMC article.
Additional boosting to the RV144 vaccine regimen increased Fc-mediated effector function magnitude but not durability.
Shubin Z, Stanfield-Oakley S, Puangkaew J, Pitisutthithum P, Nitayaphan S, Gurunathan S, Sinangil F, Chariyalertsak S, Phanuphak N, Ake JA, O'Connell RJ, Vasan S, Akapirat S, Eller MA, Ferrari G, Paquin-Proulx D; for the RV306 Study Group. Shubin Z, et al. Among authors: akapirat s. AIDS. 2023 Aug 1;37(10):1519-1524. doi: 10.1097/QAD.0000000000003611. Epub 2023 Jun 1. AIDS. 2023. PMID: 37260254 Free PMC article. Clinical Trial.
ALVAC-HIV and AIDSVAX B/E vaccination induce improved immune responses compared with AIDSVAX B/E vaccination alone.
Costanzo MC, Paquin-Proulx D, Schuetz A, Akapirat S, Shubin Z, Kim D, Wieczorek L, Polonis VR, Trinh HV, Rao M, Anenia H, Barrera MD, Boeckelman J, Nails B, Thapa P, Zemil M, Sacdalan C, Kroon E, Kaewboon B, Tipsuk S, Jongrakthaitae S, Gurunathan S, Sinangil F, Kim JH, Robb ML, Ake JA, O'Connell RJ, Pitisutthithum P, Nitayaphan S, Chariyalertsak S, Eller MA, Phanuphak N, Vasan S; RV306; RV328 study groups. Costanzo MC, et al. Among authors: akapirat s. JCI Insight. 2023 May 8;8(9):e167664. doi: 10.1172/jci.insight.167664. JCI Insight. 2023. PMID: 37154156 Free PMC article.
Dynamics of Human Immunodeficiency Virus-1 Genetic Diversification During Acute Infection.
Song H, Bose M, Pinyakorn S, Sanders-Buell E, O'Sullivan AM, Silas D, Trichavaroj R, Nuntapinit B, Pham PT, Akapirat S, Kroon E, de Souza M, Gramzinski R, Michael NL, Robb ML, Vasan S, Tovanabutra S, Ananworanich J. Song H, et al. Among authors: akapirat s. Open Forum Infect Dis. 2020 Sep 12;7(10):ofaa429. doi: 10.1093/ofid/ofaa429. eCollection 2020 Oct. Open Forum Infect Dis. 2020. PMID: 33748316 Free PMC article.
Viral vector delivered immunogen focuses HIV-1 antibody specificity and increases durability of the circulating antibody recall response.
Williams LD, Shen X, Sawant SS, Akapirat S, Dahora LC, Tay MZ, Stanfield-Oakley S, Wills S, Goodman D, Tenney D, Spreng RL, Zhang L, Yates NL, Montefiori DC, Eller MA, Easterhoff D, Hope TJ, Rerks-Ngarm S, Pittisuttithum P, Nitayaphan S, Excler JL, Kim JH, Michael NL, Robb ML, O'Connell RJ, Karasavvas N, Vasan S, Ferrari G, Tomaras GD; RV305 study team. Williams LD, et al. Among authors: akapirat s. PLoS Pathog. 2023 May 31;19(5):e1011359. doi: 10.1371/journal.ppat.1011359. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37256916 Free PMC article.
Characterization of Cellular Immune Responses in Thai Individuals With and Without HIV-Associated Neurocognitive Disorders.
Ratto-Kim S, Schuetz A, Sithinamsuwan P, Barber J, Hutchings N, Lerdlum S, Fletcher JLK, Phuang-Ngern Y, Chuenarom W, Tipsuk S, Pothisri M, Jadwattanakul T, Jirajariyavej S, Sajjaweerawan C, Akapirat S, Chalermchai T, Suttichom D, Kaewboon B, Prueksakaew P, Karnsomlap P, Clifford D, Paul RH, de Souza MS, Kim JH, Ananworanich J, Valcour V. Ratto-Kim S, et al. Among authors: akapirat s. AIDS Res Hum Retroviruses. 2018 Aug;34(8):685-689. doi: 10.1089/AID.2017.0237. Epub 2018 Jun 12. AIDS Res Hum Retroviruses. 2018. PMID: 29737194 Free PMC article.
Innate immune cell activation after HIV-1 vaccine administration is associated with increased antibody production.
N'guessan KF, Machmach K, Swafford I, Costanzo MC, Wieczorek L, Kim D, Akapirat S, Polonis VR, Pitisuttithum P, Nitayaphan S, Gurunathan S, Sinangil F, Chariyalertsak S, Ake JA, O'connell RJ, Vasan S, Paquin-Proulx D. N'guessan KF, et al. Among authors: akapirat s. Front Immunol. 2024 Feb 13;15:1339727. doi: 10.3389/fimmu.2024.1339727. eCollection 2024. Front Immunol. 2024. PMID: 38420129 Free PMC article. Clinical Trial.
Comparison of Antibody Responses Induced by RV144, VAX003, and VAX004 Vaccination Regimens.
Karnasuta C, Akapirat S, Madnote S, Savadsuk H, Puangkaew J, Rittiroongrad S, Rerks-Ngarm S, Nitayaphan S, Pitisuttithum P, Kaewkungwal J, Tartaglia J, Sinangil F, Francis DP, Robb ML, de Souza MS, Michael NL, Excler JL, Kim JH, O'Connell RJ, Karasavvas N. Karnasuta C, et al. Among authors: akapirat s. AIDS Res Hum Retroviruses. 2017 May;33(5):410-423. doi: 10.1089/AID.2016.0204. Epub 2017 Jan 30. AIDS Res Hum Retroviruses. 2017. PMID: 28006952 Free PMC article. Clinical Trial.
44 results