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Page 1
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution.
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O, Cerami E, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J, Johnson BE, Lau KS, Lively T, Mazzilli SA, Pe'er D, Santagata S, Shalek AK, Schapiro D, Snyder MP, Sorger PK, Spira AE, Srivastava S, Tan K, West RB, Williams EH; Human Tumor Atlas Network. Rozenblatt-Rosen O, et al. Cell. 2020 Apr 16;181(2):236-249. doi: 10.1016/j.cell.2020.03.053. Cell. 2020. PMID: 32302568 Free PMC article. Review.
CAR T-cell-mediated delivery of bispecific innate immune cell engagers for neuroblastoma.
Pascual-Pasto G, McIntyre B, Hines MG, Giudice AM, Garcia-Gerique L, Hoffmann J, Mishra P, Matlaga S, Lombardi S, Shraim R, Schürch PM, Yarmarkovich M, Hofmann TJ, Alikarami F, Martinez D, Tsang M, Gil-de-Gómez L, Spear TT, Bernt KM, Wolpaw AJ, Dimitrov DS, Li W, Bosse KR. Pascual-Pasto G, et al. Among authors: alikarami f. Nat Commun. 2024 Aug 21;15(1):7141. doi: 10.1038/s41467-024-51337-2. Nat Commun. 2024. PMID: 39164224 Free PMC article.
Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia.
Chen C, Yu W, Alikarami F, Qiu Q, Chen CH, Flournoy J, Gao P, Uzun Y, Fang L, Davenport JW, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Felix CA, Wu H, Brown PA, Guest EM, Barrett DM, Bernt KM, Tan K. Chen C, et al. Among authors: alikarami f. Blood. 2022 Apr 7;139(14):2198-2211. doi: 10.1182/blood.2021013442. Blood. 2022. PMID: 34864916 Free PMC article.
GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.
Alikarami F, Xie HM, Riedel SS, Goodrow HT, Barrett DR, Mahdavi L, Lenard A, Chen C, Yamauchi T, Danis E, Cao Z, Tran VL, Jung MM, Li Y, Huang H, Shi J, Tan K, Teachey DT, Bresnick EH, Neff TA, Bernt KM. Alikarami F, et al. Blood. 2025 May 8;145(19):2179-2195. doi: 10.1182/blood.2024025761. Blood. 2025. PMID: 39841459
Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome.
Chen C, Xu J, Sussman JH, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding YY, Chen CH, Li EY, Yang A, Qin X, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes AD, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt KM, Teachey DT, Tan K. Chen C, et al. Among authors: alikarami f. Blood. 2025 Jun 5;145(23):2685-2700. doi: 10.1182/blood.2024027270. Blood. 2025. PMID: 40089994 Free PMC article.
ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency.
Cao Z, Budinich KA, Huang H, Ren D, Lu B, Zhang Z, Chen Q, Zhou Y, Huang YH, Alikarami F, Kingsley MC, Lenard AK, Wakabayashi A, Khandros E, Bailis W, Qi J, Carroll MP, Blobel GA, Faryabi RB, Bernt KM, Berger SL, Shi J. Cao Z, et al. Among authors: alikarami f. Mol Cell. 2021 Sep 2;81(17):3604-3622.e10. doi: 10.1016/j.molcel.2021.07.018. Epub 2021 Aug 5. Mol Cell. 2021. PMID: 34358447 Free PMC article.
Editor's Note: Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia.
Liu Y, Li Q, Alikarami F, Barrett DR, Mahdavi L, Li H, Tang S, Khan TA, Michino M, Hill C, Song L, Yang L, Li Y, Pokharel SP, Stamford AW, Liverton N, Renzetti LM, Taylor S, Watt GF, Ladduwahetty T, Kargman S, Meinke PT, Foley MA, Shi J, Li H, Carroll M, Chen CW, Gardini A, Maillard I, Huggins DJ, Bernt KM, Wan L. Liu Y, et al. Among authors: alikarami f. Cancer Discov. 2025 Jun 3;15(6):1297-1298. doi: 10.1158/2159-8290.CD-25-0674. Cancer Discov. 2025. PMID: 40457837 Free PMC article. No abstract available.
Targeting GPC2 on Intraocular and CNS Metastatic Retinoblastomas with Local and Systemic Delivery of CAR T Cells.
Pascual-Pasto G, McIntyre B, Giudice AM, Alikarami F, Morrissey A, Matlaga S, Hofmann TJ, Burgueño V, Harvey K, Martinez D, Shah AC, Foster JB, Pogoriler J, Eagle RC, Carcaboso AM, Shields CL, Leahey AM, Bosse KR. Pascual-Pasto G, et al. Among authors: alikarami f. Clin Cancer Res. 2024 Aug 15;30(16):3578-3591. doi: 10.1158/1078-0432.CCR-24-0221. Clin Cancer Res. 2024. PMID: 38864848 Free PMC article.
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Hartmann M, Schönung M, Rajak J, Maurer V, Hai L, Bauer K, Hakobyan M, Stäble S, Langstein J, Jardine L, Roelz R, Bohler S, Khabirova E, Maag AH, Vonficht D, Lebrecht D, Bernt KM, Tan K, Chen C, Alikarami F, Meyer J, Wang J, Boch T, Flore V, Lutsik P, Milsom MD, Raffel S, Buske C, Haas S, Haniffa M, Mallm JP, Behjati S, Bonder MJ, Frohling S, Stieglitz E, Niemeyer CM, Hey J, Flotho C, Plass C, Erlacher M, Schlesner M, Lipka DB. Hartmann M, et al. Among authors: alikarami f. Blood Cancer Discov. 2025 Dec 5. doi: 10.1158/2643-3230.BCD-25-0246. Online ahead of print. Blood Cancer Discov. 2025. PMID: 41348944
Upfront menin-inhibitor resistance in multiply pretreated leukemias.
Mahdavi L, Alikarami F, Goodrow H, Lenard A, Riedel SS, Libbrecht C, Bowser I, Tasian SK, Falkenstein CD, Manning B, Skuli S, Carroll MP, Wertheim G, Cai SF, McGeehan G, Yu S, Shi J, Xie HM, Bernt KM. Mahdavi L, et al. Among authors: alikarami f. Exp Hematol. 2026 Jan;153:105268. doi: 10.1016/j.exphem.2025.105268. Epub 2025 Sep 28. Exp Hematol. 2026. PMID: 41027490
24 results