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Page 1
TNIK is a conserved regulator of glucose and lipid metabolism in obesity.
Pham TCP, Dollet L, Ali MS, Raun SH, Møller LLV, Jafari A, Ditzel N, Andersen NR, Fritzen AM, Gerhart-Hines Z, Kiens B, Suomalainen A, Simpson SJ, Salling Olsen M, Kieser A, Schjerling P, Nieminen AI, Richter EA, Havula E, Sylow L. Pham TCP, et al. Sci Adv. 2023 Aug 9;9(32):eadf7119. doi: 10.1126/sciadv.adf7119. Epub 2023 Aug 9. Sci Adv. 2023. PMID: 37556547 Free PMC article.
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Miranda-Cervantes A, Fritzen AM, Raun SH, Hodek O, Møller LLV, Johann K, Deisen L, Gregorevic P, Gudiksen A, Artati A, Adamski J, Andersen NR, Sigvardsen CM, Carl CS, Voldstedlund CT, Kjøbsted R, Hauck SM, Schjerling P, Jensen TE, Cebrian-Serrano A, Jähnert M, Gottmann P, Burtscher I, Lickert H, Pilegaard H, Schürmann A, Tschöp MH, Moritz T, Müller TD, Sylow L, Kiens B, Richter EA, Kleinert M. Miranda-Cervantes A, et al. Nat Commun. 2025 Jan 2;16(1):345. doi: 10.1038/s41467-024-55036-w. Nat Commun. 2025. PMID: 39746949 Free PMC article.
Skeletal muscle Rac1 mediates exercise training adaptations towards muscle glycogen resynthesis and protein synthesis.
Raun SH, Henriquez-Olguín C, Frank E, Schlabs F, Hahn NJ, Knudsen JR, Ali MS, Andersen NR, Møller LLV, Davey J, Qian H, Coelho A, Carl CS, Voldstedlund CT, Kiens B, Holmdahl R, Gregorevic P, Jensen TE, Deshmukh AS, Richter EA, Sylow L. Raun SH, et al. Redox Biol. 2025 Oct;86:103844. doi: 10.1016/j.redox.2025.103844. Epub 2025 Aug 28. Redox Biol. 2025. PMID: 40886619 Free PMC article.
Housing Temperature Impacts the Systemic and Tissue-Specific Molecular Responses to Cancer in Mice.
Irazoki A, Frank E, Pham TCP, Braun JL, Ehrlich AM, Haid M, Riols F, Hansen CHF, Jørgensen AR, Andersen NR, Hidalgo-Corbacho L, Meneses-Valdes R, Ali MS, Raun SH, Modvig JL, Gallero S, Larsen S, Gerhart-Hines Z, Jensen TE, Rohm M, Treebak JT, Fajardo VA, Sylow L. Irazoki A, et al. J Cachexia Sarcopenia Muscle. 2025 Apr;16(2):e13781. doi: 10.1002/jcsm.13781. J Cachexia Sarcopenia Muscle. 2025. PMID: 40237521 Free PMC article.
The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms.
Pham TCP, Raun SH, Havula E, Henriquez-Olguín C, Rubalcava-Gracia D, Frank E, Fritzen AM, Jannig PR, Andersen NR, Kruse R, Ali MS, Irazoki A, Halling JF, Ringholm S, Needham EJ, Hansen S, Lemminger AK, Schjerling P, Petersen MH, de Almeida ME, Jensen TE, Kiens B, Hostrup M, Larsen S, Ørtenblad N, Højlund K, Kjær M, Ruas JL, Trifunovic A, Wojtaszewski JFP, Nielsen J, Qvortrup K, Pilegaard H, Richter EA, Sylow L. Pham TCP, et al. Nat Commun. 2024 Nov 13;15(1):9826. doi: 10.1038/s41467-024-54183-4. Nat Commun. 2024. PMID: 39537626 Free PMC article.
Activin receptor type IIA/IIB blockade increases muscle mass and strength, but compromises glycemic control in mice.
Carlsson M, Frank E, Màrmol JM, Ali MS, Raun SH, Battey E, Andersen NR, Irazoki A, Lund C, Henríquez-Olguin C, Højfeldt MK, Blomquist P, Bromer FD, Mocciaro G, Lodberg A, Folsted Andersen CB, Eijken M, Fritzen AM, Knudsen JR, Richter EA, Sylow L. Carlsson M, et al. Mol Metab. 2025 Dec;102:102261. doi: 10.1016/j.molmet.2025.102261. Epub 2025 Sep 27. Mol Metab. 2025. PMID: 41022302 Free PMC article.
The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action.
Møller LLV, Ali MS, Davey J, Raun SH, Andersen NR, Long JZ, Qian H, Jeppesen JF, Henriquez-Olguin C, Frank E, Jensen TE, Højlund K, Wojtaszewski JFP, Nielsen J, Chiu TT, Jedrychowski MP, Gregorevic P, Klip A, Richter EA, Sylow L. Møller LLV, et al. Proc Natl Acad Sci U S A. 2023 Jul 4;120(27):e2211041120. doi: 10.1073/pnas.2211041120. Epub 2023 Jun 26. Proc Natl Acad Sci U S A. 2023. PMID: 37364105 Free PMC article.
40 results