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Multicenter Study
. 2013 May-Jun;17(3):346-52.
doi: 10.1016/j.bjid.2012.10.022. Epub 2013 May 14.

Frequency of microorganisms isolated in patients with bacteremia in intensive care units in Colombia and their resistance profiles

Jorge Alberto Cortes  1 , Aura Lucía Leal, Anita María Montañez, Giancarlo Buitrago, Juan Sebastián Castillo, Lucy Guzman; GREBO
Collaborators, Affiliations
Multicenter Study

Frequency of microorganisms isolated in patients with bacteremia in intensive care units in Colombia and their resistance profiles

Jorge Alberto Cortes et al. Braz J Infect Dis. 2013 May-Jun.

Abstract

Objective: The aim of this study was to describe the most frequently found bacterial microorganisms in bloodstream isolates taken from patients in intensive care units in Colombia and their resistance profiles.

Methods: This was a multicentre descriptive observational study that was carried out between January 2001 and June 2008 with laboratory data from 33 participating hospitals in a surveillance network.

Results: The most frequently found microorganisms were coagulase-negative Staphylococci 39.6%, Staphylococcus aureus 12.3%, Klebsiella pneumoniae 8.2%, Escherichia coli 5.7%, Acinetobacter baumannii, 4.0% and Pseudomonas aeruginosa 3.8%. Coagulase-negative Staphylococci registered greater than 70% oxacillin resistance rate. S. aureus presented a change in its multiresistance profile during the years of follow-up. There was a trend towards a lower resistance rate among E. coli and K. pneumoniae isolates during the study period while A. baumannii carbapenem resistance rate exceeded 50%.

Discussion: There has been a change in the frequency of species being isolated with a higher frequency of enterobacteriaceae compared to Gram-positive microorganisms, in general with a high resistance rate.

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Figures

Fig. 1
Fig. 1
Frequency of selected Gram-positive cocci associated with bloodstream infections in patients in intensive care units, excluding coagulase negative Staphylococci. 2001–first half of 2008.
Fig. 2
Fig. 2
Frequency of selected Gram-negative bacilli associated with bloodstream infections in patients admitted to ICU. 2001–first half of 2008.
Fig. 3
Fig. 3
Tendency of oxacillin-resistant S. aureus, according to resistant phenotype tendency. 2001–first half of 2008. GREBO.
Fig. 4
Fig. 4
Resistance profile of P. aeruginosa causing bloodstream infections in patients admitted to ICU. 2001–first half of 2008. GREBO. Each bar represents the rate of resistance to the selected antibiotic. Number of isolates tested is below each year.
Fig. 5
Fig. 5
Resistance profile for A. baumannii causing bloodstream infections in patients admitted to ICU. 2001–first half of 2008. GREBO. Each bar represents the rate of resistance to the selected antibiotic. Number of isolates tested is below each year.
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References

    1. Lizaso D., Aguilera C.K., Correa M., et al. Epidemiología y factores de riesgo de mortalidad de las bacteriemias intrahospitalarias por bacilos gramnegativos. Rev Chilena Infectol. 2008;25:368–373. - PubMed
    1. WHO. Prevention of hospital-acquired infections: a practical guide; 2002 (updated 2002; cited). Available from: http://www.who.int/csr/resources/publications/drugresist/WHO_CDS_CSR_EPH... [Revised: march 7, 2011].
    1. Ribas R.M., Freitas C., Gontijo Filho P.P. Nosocomial bloodstream infections: organisms, risk factors and resistant phenotypes in the Brazilian University Hospital. Braz J Infect Dis. 2007;11:351–354. - PubMed
    1. Leal A.L., Eslava-Schmalbach J., Alvarez C., Buitrago G., Mendez M. Canales endémicos y marcadores de resistencia bacteriana, en instituciones de tercer nivel de Bogotá, Colombia. Rev Salud Publica (Bogota) 2006;8:59–70. - PubMed
    1. Institute CaLS . CLSI; Wayne, PA: 2008. M100-S18, performance standards for antimicrobial susceptibility testing. Eighteen informational supplement.

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