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59 results

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Page 1
Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates.
Yu YJ, Atwal JK, Zhang Y, Tong RK, Wildsmith KR, Tan C, Bien-Ly N, Hersom M, Maloney JA, Meilandt WJ, Bumbaca D, Gadkar K, Hoyte K, Luk W, Lu Y, Ernst JA, Scearce-Levie K, Couch JA, Dennis MS, Watts RJ. Yu YJ, et al. Among authors: atwal jk. Sci Transl Med. 2014 Nov 5;6(261):261ra154. doi: 10.1126/scitranslmed.3009835. Sci Transl Med. 2014. PMID: 25378646
Leveraging neonatal Fc receptor (FcRn) to enhance antibody transport across the blood brain barrier.
Lafrance-Vanasse J, Sadekar SS, Yang Y, Yadav DB, Meilandt WJ, Wetzel-Smith MK, Cai H, Crowell SR, Nguyen V, Lee V, Chih B, Kwong M, Chan P, Santagostino S, Lee D, Chung S, Lazar GA, Ernst JA, Atwal JK. Lafrance-Vanasse J, et al. Among authors: atwal jk. Nat Commun. 2025 May 3;16(1):4143. doi: 10.1038/s41467-025-59447-1. Nat Commun. 2025. PMID: 40319060 Free PMC article.
Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid.
Sadekar SS, Bowen M, Cai H, Jamalian S, Rafidi H, Shatz-Binder W, Lafrance-Vanasse J, Chan P, Meilandt WJ, Oldendorp A, Sreedhara A, Daugherty A, Crowell S, Wildsmith KR, Atwal J, Fuji RN, Horvath J. Sadekar SS, et al. Among authors: atwal j. Clin Pharmacol Ther. 2022 Apr;111(4):826-834. doi: 10.1002/cpt.2531. Epub 2022 Feb 23. Clin Pharmacol Ther. 2022. PMID: 35064573 Free PMC article. Review.
ERBB2/HER2 Alterations in ctDNA and Metachronous Tissues of Patients with Metastatic Urothelial Cancer.
Vandekerkhove G, Murtha AJ, Müller DC, Stephenson M, Rostin K, Munzur AD, Vasquez-Rios C, Nikkola J, Sipola J, Annala M, Herberts C, Fung E, Atwal J, Al-Subaie S, Parekh K, Bernales CQ, Donnellan G, Finch D, Noonan K, Ko JJ, Ozgun G, Nappi L, Kollmannsberger C, Lavoie JM, Parimi S, Todenhöfer T, Ost P, Wang G, Black PC, Maurice-Dror C, Chi KN, Eigl BJ, Wyatt AW. Vandekerkhove G, et al. Among authors: atwal j. Clin Cancer Res. 2025 Sep 2;31(17):3725-3741. doi: 10.1158/1078-0432.CCR-24-3912. Clin Cancer Res. 2025. PMID: 40540011
59 results