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. 2020;151(2 & 3):241-243.
doi: 10.4103/ijmr.IJMR_577_20.

Transmission electron microscopy imaging of SARS-CoV-2

Sharda Prasad  1 , Varsha Potdar  2 , Sarah Cherian  3 , Priya Abraham  4 , Atanu Basu  5 ; ICMR-NIV NIC Team
Collaborators, Affiliations

Transmission electron microscopy imaging of SARS-CoV-2

Sharda Prasad et al. Indian J Med Res. 2020.
No abstract available

PubMed Disclaimer

Conflict of interest statement

None

Figures

Figure
Figure
Transmission electron microscopy imaging of COVID-19. (A) A representative negative-stained COVID-19 particle showing morphodiagnostic features of family Coronaviridae. (B) Defocussed image of the same particle resolving the virus envelope glycoprotein morphology in finer details. The boxed area A shows a tetramer-like aggregate of four distinct peplomers, arrows shown by B show a more orthodox morphology of coronavirus surface projections. M indicates the matrix of the virus particle. C shows a distinct 'peplomer head' with negative stain silhouette. The area D is interesting as possible linear projections could be imaged. Five distinct peplomers could be imaged as shown by the arrows. (C) A highly magnified processed image for pixel corrections shows a distinct evidence of direct 'stalk' connecting the peplomer to the virion surface. The peplomers are shown with asterisk and the stalk with an arrow. Magnification bars are built into the micrographs.
See this image and copyright information in PMC

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