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87 results

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Page 1
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety.
Smole A, Benton A, Poussin MA, Eiva MA, Mezzanotte C, Camisa B, Greco B, Sharma P, Minutolo NG, Gray F, Bear AS, Baroja ML, Cummins C, Xu C, Sanvito F, Goldgewicht AL, Blanchard T, Rodriguez-Garcia A, Klichinsky M, Bonini C, June CH, Posey AD Jr, Linette GP, Carreno BM, Casucci M, Powell DJ Jr. Smole A, et al. Among authors: bear as. Cancer Cell. 2022 Dec 12;40(12):1470-1487.e7. doi: 10.1016/j.ccell.2022.11.006. Cancer Cell. 2022. PMID: 36513049 Free PMC article.
Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.
Bear AS, Nadler RB, O'Hara MH, Stanton KL, Xu C, Saporito RJ, Rech AJ, Baroja ML, Blanchard T, Elliott MH, Ford MJ, Jones R, Patel S, Brennan A, O'Neil Z, Powell DJ Jr, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. J Clin Invest. 2024 Sep 17;134(21):e175790. doi: 10.1172/JCI175790. J Clin Invest. 2024. PMID: 39287991 Free PMC article. Clinical Trial.
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.
Bear AS, Blanchard T, Cesare J, Ford MJ, Richman LP, Xu C, Baroja ML, McCuaig S, Costeas C, Gabunia K, Scholler J, Posey AD Jr, O'Hara MH, Smole A, Powell DJ Jr, Garcia BA, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. Nat Commun. 2021 Jul 16;12(1):4365. doi: 10.1038/s41467-021-24562-2. Nat Commun. 2021. PMID: 34272369 Free PMC article.
Mutant KRAS peptide targeted CAR-T cells engineered for cancer therapy.
Benton A, Liu J, Poussin MA, Lang Goldgewicht A, Udawela M, Bear AS, Wellhausen N, Carreno BM, Smith PM, Beasley MD, Kiefel BR, Powell DJ Jr. Benton A, et al. Among authors: bear as. Cancer Cell. 2025 Jul 14;43(7):1365-1376.e5. doi: 10.1016/j.ccell.2025.05.006. Epub 2025 Jun 5. Cancer Cell. 2025. PMID: 40480232
Ancient origin of an urban underground mosquito.
Haba Y, Aardema ML, Afonso MO, Agramonte NM, Albright J, Alho AM, Almeida APG, Alout H, Alten B, Altinli M, Amara Korba R, Andreadis SS, Anghel V, Arich S, Arsenault-Benoit A, Atyame C, Aubry F, Avila FW, Ayala D, Azrag RS, Babayan L, Bear A, Becker N, Bega AG, Bejarano S, Ben-Avi I, Benoit JB, Boubidi SC, Bradshaw WE, Bravo-Barriga D, Bueno-Marí R, Bušić N, Čabanová V, Cabeje B, Caputo B, Cardo MV, Carpenter S, Carreton E, Chouaïbou MS, Christian M, Coetzee M, Conner WR, Cornel A, Culverwell CL, Cupina AI, De Wolf K, Deblauwe I, Deegan B, Delacour-Estrella S, Torre AD, Diaz D, Dool SE, Dos Anjos VL, Dugassa S, Ebrahimi B, Eisa SYM, Elissa N, Fallatah SAB, Faraji A, Fedorova MV, Ferrill E, Fonseca DM, Foss KA, Foxi C, França CM, Fricker SR, Fritz ML, Frontera E, Fuehrer HP, Futami K, Ghallab EHS, Girod R, Gordeev MI, Greer D, Gschwind M, Guarido MM, Guat Ney T, Gunay F, Haklay E, Hamad AAE, Hang J, Hardy CM, Hartle JW, Hesson JC, Higa Y, Holzapfel CM, Honnen AC, Ionica AM, Jones L, Kadriaj P, Kamal HA, Kamdem C, Karagodin DA, Kasai S, Kavran M, Khater EIM, Kiene F, Kim HC, Kioulos I, Klein A, Klemenčić M, Klobučar A, Knutson E, Koenraadt CJM, Kothera L, Kreienbühl P, Labbé … See abstract for full author list ➔ Haba Y, et al. Among authors: bear a. bioRxiv [Preprint]. 2025 Feb 5:2025.01.26.634793. doi: 10.1101/2025.01.26.634793. bioRxiv. 2025. PMID: 39975080 Free PMC article. Preprint.
What comes to mind?
Bear A, Bensinger S, Jara-Ettinger J, Knobe J, Cushman F. Bear A, et al. Cognition. 2020 Jan;194:104057. doi: 10.1016/j.cognition.2019.104057. Epub 2019 Sep 26. Cognition. 2020. PMID: 31505322
LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma.
Blanchard T, Faridi P, Xu C, Bear AS, Rasool RU, Huang G, Lim TCC, Ayala R, Gabunia K, Ji M, Posey AD Jr, Scholler J, Asangani IA, Purcell AW, Linette GP, June CH, Carreno BM. Blanchard T, et al. Among authors: bear as. Sci Rep. 2025 Apr 15;15(1):13007. doi: 10.1038/s41598-025-96877-9. Sci Rep. 2025. PMID: 40234527 Free PMC article.
87 results