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Page 1
Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis.
Chalmers JD, Burgel PR, Daley CL, De Soyza A, Haworth CS, Mauger D, Loebinger MR, McShane PJ, Ringshausen FC, Blasi F, Shteinberg M, Mange K, Teper A, Fernandez C, Zambrano M, Fan C, Zhang X, Metersky ML; ASPEN Investigators. Chalmers JD, et al. N Engl J Med. 2025 Apr 24;392(16):1569-1581. doi: 10.1056/NEJMoa2411664. N Engl J Med. 2025. PMID: 40267423 Clinical Trial.
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases.
Barturen G, Babaei S, Català-Moll F, Martínez-Bueno M, Makowska Z, Martorell-Marugán J, Carmona-Sáez P, Toro-Domínguez D, Carnero-Montoro E, Teruel M, Kerick M, Acosta-Herrera M, Le Lann L, Jamin C, Rodríguez-Ubreva J, García-Gómez A, Kageyama J, Buttgereit A, Hayat S, Mueller J, Lesche R, Hernandez-Fuentes M, Juarez M, Rowley T, White I, Marañón C, Gomes Anjos T, Varela N, Aguilar-Quesada R, Garrancho FJ, López-Berrio A, Rodriguez Maresca M, Navarro-Linares H, Almeida I, Azevedo N, Brandão M, Campar A, Faria R, Farinha F, Marinho A, Neves E, Tavares A, Vasconcelos C, Trombetta E, Montanelli G, Vigone B, Alvarez-Errico D, Li T, Thiagaran D, Blanco Alonso R, Corrales Martínez A, Genre F, López Mejías R, Gonzalez-Gay MA, Remuzgo S, Ubilla Garcia B, Cervera R, Espinosa G, Rodríguez-Pintó I, De Langhe E, Cremer J, Lories R, Belz D, Hunzelmann N, Baerlecken N, Kniesch K, Witte T, Lehner M, Stummvoll G, Zauner M, Aguirre-Zamorano MA, Barbarroja N, Castro-Villegas MC, Collantes-Estevez E, de Ramon E, Díaz Quintero I, Escudero-Contreras A, Fernández Roldán MC, Jiménez Gómez Y, Jiménez Moleón I, Lopez-Pedrera R, Ortega-Castro R, Ortego N, Raya E, Artusi C, Gerosa M, Meroni PL, Schio… See abstract for full author list ➔ Barturen G, et al. Among authors: belz d. Arthritis Rheumatol. 2021 Jun;73(6):1073-1085. doi: 10.1002/art.41610. Epub 2021 Apr 26. Arthritis Rheumatol. 2021. PMID: 33497037 Free article.
A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome.
Soret P, Le Dantec C, Desvaux E, Foulquier N, Chassagnol B, Hubert S, Jamin C, Barturen G, Desachy G, Devauchelle-Pensec V, Boudjeniba C, Cornec D, Saraux A, Jousse-Joulin S, Barbarroja N, Rodríguez-Pintó I, De Langhe E, Beretta L, Chizzolini C, Kovács L, Witte T; PRECISESADS Clinical Consortium; PRECISESADS Flow Cytometry Consortium; Bettacchioli E, Buttgereit A, Makowska Z, Lesche R, Borghi MO, Martin J, Courtade-Gaiani S, Xuereb L, Guedj M, Moingeon P, Alarcón-Riquelme ME, Laigle L, Pers JO. Soret P, et al. Nat Commun. 2021 Jun 10;12(1):3523. doi: 10.1038/s41467-021-23472-7. Nat Commun. 2021. PMID: 34112769 Free PMC article.
A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome.
Casares-Marfil D, Martínez-Bueno M, Borghi MO, Pons-Estel G; PRECISESADS Clinical Consortium; Reales G, Zuo Y, Espinosa G, Radstake T, van den Hoogen LL, Wallace C, Guthridge J, James JA, Cervera R, Meroni PL, Martin J, Knight JS, Alarcón-Riquelme ME, Sawalha AH. Casares-Marfil D, et al. Arthritis Rheumatol. 2024 Nov;76(11):1623-1634. doi: 10.1002/art.42947. Epub 2024 Aug 11. Arthritis Rheumatol. 2024. PMID: 38973605
Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis.
Parodis I, Lindblom J, Toro-Domínguez D, Beretta L, Borghi MO, Castillo J, Carnero-Montoro E, Enman Y, Mohan C, Alarcón-Riquelme ME, Barturen G, Nikolopoulos D; PRECISESADS Clinical Consortium. Parodis I, et al. Kidney Int Rep. 2024 Mar 13;9(6):1817-1835. doi: 10.1016/j.ekir.2024.03.014. eCollection 2024 Jun. Kidney Int Rep. 2024. PMID: 38899167 Free PMC article.
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants.
Castellini-Pérez O, Povedano E, Barturen G, Martínez-Bueno M, Iakovliev A, Kerick M, López-Domínguez R, Marañón C, Martín J, Ballestar E; PRECISEADS Clinical Consortium; PRECISEADS Flow Cytometry Study Group; Borghi MO, Qiu W, Zhu C, Shankara S, Spiliopoulou A, de Rinaldis E, Carnero-Montoro E, Alarcón-Riquelme ME. Castellini-Pérez O, et al. NPJ Genom Med. 2024 Jul 16;9(1):38. doi: 10.1038/s41525-024-00420-0. NPJ Genom Med. 2024. PMID: 39013887 Free PMC article.
Novel IgG and IgA autoantibodies validated in two independent cohorts are associated with disease activity and determine organ manifestations in systemic lupus erythematosus: implications for anti-LIN28A, anti-HMGN5, anti-IRF5, and anti-TGIF1.
Lindblom J, Lagutkin D, Sherina N, Idborg H, Beretta L, Borghi MO; PRECISESADS Clinical Consortium; Peyper JM, Barturen G, Jakobsson PJ, Alarcón-Riquelme ME, Nikolopoulos D, Parodis I. Lindblom J, et al. Ann Rheum Dis. 2025 Jul;84(7):1164-1179. doi: 10.1016/j.ard.2025.04.008. Epub 2025 May 9. Ann Rheum Dis. 2025. PMID: 40348637 Free article.
Call to Action: How Can We Promote the Development of New Pharmacologic Treatments in Chronic Obstructive Pulmonary Disease?
Belz DC, Putcha N, Alupo P, Siddharthan T, Baugh A, Hopkinson N, Castaldi P, Papi A, Mannino D, Miravitlles M, Han M, Fabbri LM, Montes de Oca M, Krishnan JA, Singh D, Martinez FJ, Hansel NN, Calverley P. Belz DC, et al. Am J Respir Crit Care Med. 2024 Dec 1;210(11):1300-1307. doi: 10.1164/rccm.202311-2180PP. Am J Respir Crit Care Med. 2024. PMID: 39405496 No abstract available.
49 results