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Page 1
Showing results for blocks t
Search for Bloks T instead (2 results)
How to block and tackle the face.
Zide BM, Swift R. Zide BM, et al. Plast Reconstr Surg. 1998 Mar;101(3):840-51. doi: 10.1097/00006534-199803000-00041. Plast Reconstr Surg. 1998. PMID: 9500408
Surgeons should know a fail-safe method of nerve blocks. Fresh cadaver dissections are used to demonstrate a series of eight regional nerve-blocking routes. This sequence of bilateral blocks will routinely provide profound full facial anesthesia. Certain grou …
Surgeons should know a fail-safe method of nerve blocks. Fresh cadaver dissections are used to demonstrate a series of eight regional …
Lercanidipine and T-type calcium current.
Cerbai E, Mugelli A. Cerbai E, et al. Eur Rev Med Pharmacol Sci. 2018 Jun;22(12):4025-4031. doi: 10.26355/eurrev_201806_15289. Eur Rev Med Pharmacol Sci. 2018. PMID: 29949180 Free article.
Our previous data demonstrated that lercanidipine blocks L-type calcium channels (CaL). However, no data are available concerning its effects on T-type calcium channels (CaT). ...CONCLUSIONS: All CCBs examined in this study showed both T- and L-channel blo …
Our previous data demonstrated that lercanidipine blocks L-type calcium channels (CaL). However, no data are available concerning its …
Charybdotoxin blocks voltage-gated K+ channels in human and murine T lymphocytes.
Sands SB, Lewis RS, Cahalan MD. Sands SB, et al. J Gen Physiol. 1989 Jun;93(6):1061-74. doi: 10.1085/jgp.93.6.1061. J Gen Physiol. 1989. PMID: 2475579 Free PMC article.
Nanomolar concentrations of charbdotoxin (CTX), a purified peptide component of Leiurus quinquestriatus venom known to block Ca2+-activated K+ channels from muscle, blocked "type n" voltage-gated K+ channels in human T lymphoid cells. ...Noxiustoxin (NTX), a …
Nanomolar concentrations of charbdotoxin (CTX), a purified peptide component of Leiurus quinquestriatus venom known to block Ca2+-act …
Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function.
Fanunza E, Iampietro M, Distinto S, Corona A, Quartu M, Maccioni E, Horvat B, Tramontano E. Fanunza E, et al. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00530-20. doi: 10.1128/AAC.00530-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32366711 Free PMC article.
The mechanism of action of the most active compound, quercetin, showing a half-maximal inhibitory concentration (IC(50)) of 7.4 muM, was characterized to significantly restore the IFN-I signaling cascade, blocked by VP24, by directly interfering with the VP24 binding to ka …
The mechanism of action of the most active compound, quercetin, showing a half-maximal inhibitory concentration (IC(50)) of 7.4 muM, was cha …
Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy.
DeSilva DR, Jones EA, Favata MF, Jaffee BD, Magolda RL, Trzaskos JM, Scherle PA. DeSilva DR, et al. J Immunol. 1998 May 1;160(9):4175-81. J Immunol. 1998. PMID: 9574517
The block in T cell proliferation was mediated by down-regulating IL-2 mRNA levels. Blocking Ag-induced proliferation by inhibiting MEK did not induce anergy, unlike treatments that block entry into the cell cycle following antigenic stimulation. Surpr …
The block in T cell proliferation was mediated by down-regulating IL-2 mRNA levels. Blocking Ag-induced proliferation b …
RB and cell cycle progression.
Giacinti C, Giordano A. Giacinti C, et al. Oncogene. 2006 Aug 28;25(38):5220-7. doi: 10.1038/sj.onc.1209615. Oncogene. 2006. PMID: 16936740 Review.
It has been shown that Rb protein (pRb) is responsible for a major G1 checkpoint, blocking S-phase entry and cell growth. The retinoblastoma family includes three members, Rb/p105, p107 and Rb2/p130, collectively referred to as 'pocket proteins'. ...
It has been shown that Rb protein (pRb) is responsible for a major G1 checkpoint, blocking S-phase entry and cell growth. The retinob …
Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis.
Coisne C, Mao W, Engelhardt B. Coisne C, et al. J Immunol. 2009 May 15;182(10):5909-13. doi: 10.4049/jimmunol.0803418. J Immunol. 2009. PMID: 19414741
The efficiency of natalizumab to block T cell adhesion to the inflamed BBB was found to be more effective in EAE than in acute systemic TNF-alpha-induced inflammation. Our data demonstrate that alpha(4) integrin-mediated adhesion of human T cells to the infla …
The efficiency of natalizumab to block T cell adhesion to the inflamed BBB was found to be more effective in EAE than in acute …
Hemin blocks TIGIT/PVR interaction and induces ferroptosis to elicit synergistic effects of cancer immunotherapy.
Zhou X, Li Y, Zhang X, Li B, Jin S, Wu M, Zhou X, Dong Q, Du J, Zhai W, Wu Y, Qiu L, Li G, Qi Y, Zhao W, Gao Y. Zhou X, et al. Sci China Life Sci. 2024 May;67(5):996-1009. doi: 10.1007/s11427-023-2472-4. Epub 2024 Feb 1. Sci China Life Sci. 2024. PMID: 38324132
In this study, the small molecule Hemin that could bind with TIGIT to block TIGIT/PVR interaction was screened by virtual molecular docking and cell-based blocking assay. ...Hemin reinvigorated the function of CD8(+) T cells to secrete IFN-gamma and the eleva …
In this study, the small molecule Hemin that could bind with TIGIT to block TIGIT/PVR interaction was screened by virtual molecular d …
Blocking effect of an immuno-suppressive agent, cynarin, on CD28 of T-cell receptor.
Dong GC, Chuang PH, Chang KC, Jan PS, Hwang PI, Wu HB, Yi M, Zhou HX, Chen HM. Dong GC, et al. Pharm Res. 2009 Feb;26(2):375-81. doi: 10.1007/s11095-008-9754-5. Epub 2008 Nov 7. Pharm Res. 2009. PMID: 18989760 Free PMC article.
This Echinacea component is the first small molecule that is able to specifically block "signal 2" of T-cell activation. METHODS: In this study, we used the AFTIR method to further confirm that cynarin effectively blocked the binding between CD80 of B-cells a …
This Echinacea component is the first small molecule that is able to specifically block "signal 2" of T-cell activation. METHO …
Block of T-type calcium channels by protoxins I and II.
Bladen C, Hamid J, Souza IA, Zamponi GW. Bladen C, et al. Mol Brain. 2014 May 9;7:36. doi: 10.1186/1756-6606-7-36. Mol Brain. 2014. PMID: 24886690 Free PMC article.
We therefore hypothesized that binding sites for certain sodium channel blocking peptide toxins may be present in T-type calcium channels. FINDINGS: The sodium channel blocker ProTx I tonically blocked native and transiently expressed T-type channels i …
We therefore hypothesized that binding sites for certain sodium channel blocking peptide toxins may be present in T-type calci …
363,870 results
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