Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression.
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Bonnal RJP, et al.
Nat Immunol. 2021 Jun;22(6):735-745. doi: 10.1038/s41590-021-00930-4. Epub 2021 May 20.
Nat Immunol. 2021.
PMID: 34017124
Using single-cell transcriptomics, we found that CD4(+) T cells infiltrating primary and metastatic colorectal cancer and non-small-cell lung cancer are highly enriched for two subsets of comparable size and suppressor function comprising forkhead box protein P3(+) T(reg) …
Using single-cell transcriptomics, we found that CD4(+) T cells infiltrating primary and metastatic colorectal cancer and non-small-cell lun …
