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1984 1
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82 results

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Page 1
De novo design of protein structure and function with RFdiffusion.
Watson JL, Juergens D, Bennett NR, Trippe BL, Yim J, Eisenach HE, Ahern W, Borst AJ, Ragotte RJ, Milles LF, Wicky BIM, Hanikel N, Pellock SJ, Courbet A, Sheffler W, Wang J, Venkatesh P, Sappington I, Torres SV, Lauko A, De Bortoli V, Mathieu E, Ovchinnikov S, Barzilay R, Jaakkola TS, DiMaio F, Baek M, Baker D. Watson JL, et al. Among authors: borst aj. Nature. 2023 Aug;620(7976):1089-1100. doi: 10.1038/s41586-023-06415-8. Epub 2023 Jul 11. Nature. 2023. PMID: 37433327 Free PMC article.
Atomically accurate de novo design of antibodies with RFdiffusion.
Bennett NR, Watson JL, Ragotte RJ, Borst AJ, See DL, Weidle C, Biswas R, Yu Y, Shrock EL, Ault R, Leung PJY, Huang B, Goreshnik I, Tam J, Carr KD, Singer B, Criswell C, Wicky BIM, Vafeados D, Sanchez MG, Kim HM, Torres SV, Chan S, Sun SM, Spear T, Sun Y, O'Reilly K, Maris JM, Sgourakis NG, Melnyk RA, Liu CC, Baker D. Bennett NR, et al. Among authors: borst aj. bioRxiv [Preprint]. 2025 Feb 28:2024.03.14.585103. doi: 10.1101/2024.03.14.585103. bioRxiv. 2025. Update in: Nature. 2025 Nov 5. doi: 10.1038/s41586-025-09721-5. PMID: 38562682 Free PMC article. Updated. Preprint.
Genomic profiling informs diagnoses and treatment in vascular anomalies.
Li D, Sheppard SE, March ME, Battig MR, Surrey LF, Srinivasan AS, Matsuoka LS, Tian L, Wang F, Seiler C, Dayneka J, Borst AJ, Matos MC, Paulissen SM, Krishnamurthy G, Nriagu B, Sikder T, Casey M, Williams L, Rangu S, O'Connor N, Thomas A, Pinto E, Hou C, Nguyen K, Pellegrino da Silva R, Chehimi SN, Kao C, Biroc L, Britt AD, Queenan M, Reid JR, Napoli JA, Low DM, Vatsky S, Treat J, Smith CL, Cahill AM, Snyder KM, Adams DM, Dori Y, Hakonarson H. Li D, et al. Among authors: borst aj. Nat Med. 2023 Jun;29(6):1530-1539. doi: 10.1038/s41591-023-02364-x. Epub 2023 Jun 1. Nat Med. 2023. PMID: 37264205 Free PMC article.
Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial.
Goldenberg NA, Kittelson JM, Abshire TC, Bonaca M, Casella JF, Dale RA, Halperin JL, Hamblin F, Kessler CM, Manco-Johnson MJ, Sidonio RF, Spyropoulos AC, Steg PG, Turpie AGG, Schulman S; Kids-DOTT Trial Investigators and the ATLAS Group. Goldenberg NA, et al. JAMA. 2022 Jan 11;327(2):129-137. doi: 10.1001/jama.2021.23182. JAMA. 2022. PMID: 35015038 Free PMC article. Clinical Trial.
Computational design of bifaceted protein nanomaterials.
Rankovic S, Carr KD, Decarreau J, Skotheim R, Kibler RD, Ols S, Lee S, Chun JH, Tooley MR, Dauparas J, Eisenach HE, Glögl M, Weidle C, Borst AJ, Baker D, King NP. Rankovic S, et al. Among authors: borst aj. bioRxiv [Preprint]. 2024 Dec 21:2024.10.18.619149. doi: 10.1101/2024.10.18.619149. bioRxiv. 2024. Update in: Nat Mater. 2025 Oct;24(10):1635-1643. doi: 10.1038/s41563-025-02295-7. PMID: 39484564 Free PMC article. Updated. Preprint.
Measuring coagulopathy in pediatric craniofacial surgery.
Borst AJ, Bonfield CM, Deenadayalan PS, Le CH, Xu M, Reddy SK. Borst AJ, et al. Blood Coagul Fibrinolysis. 2023 Sep 1;34(6):403-407. doi: 10.1097/MBC.0000000000001234. Epub 2023 Jun 12. Blood Coagul Fibrinolysis. 2023. PMID: 37395200 Review.
Computational design of non-porous pH-responsive antibody nanoparticles.
Yang EC, Divine R, Miranda MC, Borst AJ, Sheffler W, Zhang JZ, Decarreau J, Saragovi A, Abedi M, Goldbach N, Ahlrichs M, Dobbins C, Hand A, Cheng S, Lamb M, Levine PM, Chan S, Skotheim R, Fallas J, Ueda G, Lubner J, Somiya M, Khmelinskaia A, King NP, Baker D. Yang EC, et al. Among authors: borst aj. Nat Struct Mol Biol. 2024 Sep;31(9):1404-1412. doi: 10.1038/s41594-024-01288-5. Epub 2024 May 9. Nat Struct Mol Biol. 2024. PMID: 38724718 Free PMC article.
Computational design of bifaceted protein nanomaterials.
Rankovic S, Carr KD, Decarreau J, Skotheim R, Kibler RD, Ols S, Lee S, Chun JH, Tooley MR, Dauparas J, Eisenach HE, Glögl M, Weidle C, Borst AJ, Baker D, King NP. Rankovic S, et al. Among authors: borst aj. Nat Mater. 2025 Oct;24(10):1635-1643. doi: 10.1038/s41563-025-02295-7. Epub 2025 Jul 31. Nat Mater. 2025. PMID: 40745094 Free PMC article.
Smart data collection for CryoEM.
Bepler T, Borst AJ, Bouvette J, Cannone G, Chen S, Cheng A, Cheng A, Fan Q, Grollios F, Gupta H, Gupta M, Humphreys T, Kim PT, Kuang H, Li Y, Noble AJ, Punjani A, Rice WJ, Oscar S Sorzano C, Stagg SM, Strauss J, Yu L, Carragher B, Potter CS. Bepler T, et al. Among authors: borst aj. J Struct Biol. 2022 Dec;214(4):107913. doi: 10.1016/j.jsb.2022.107913. Epub 2022 Oct 28. J Struct Biol. 2022. PMID: 36341954
82 results