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36 results

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Page 1
Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM.
Chen HH, Highland HM, Frankel EG, Scartozzi AC, Zhang X, Roshani R, Sharma P, Kar A, Buchanan VL, Polikowsky HG, Petty LE, Seo J, Anwar MY, Kim D, Graff M, Young KL, Zhu W, Karastergiou K, Shaw DM, Justice AE, Fernández-Rhodes L, Krishnan M, Gutierrez A, McCormick PJ, Aguilar-Salinas CA, Tusié-Luna MT, Muñoz-Hernandez LL, Herrera-Hernandez M, Lee M, Gamazon ER, Cox NJ, Pajukanta P, Fried SK, Gordon-Larsen P, Shah RV, Fisher-Hoch SP, McCormick JB, North KE, Below JE. Chen HH, et al. Among authors: buchanan vl. Cell Genom. 2025 Mar 12;5(3):100784. doi: 10.1016/j.xgen.2025.100784. Epub 2025 Mar 4. Cell Genom. 2025. PMID: 40043711 Free PMC article.
Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Smit RAJ, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE, Buchanan VL, Chittoor G, Graff M, Guindo-Martínez M, Lu Y, Marouli E, Sakaue S, Spracklen CN, Vedantam S, Wilson EP, Chen SH, Ferreira T, Ji Y, Karaderi T, Lüll K, Machado M, Malden DE, Medina-Gomez C, Moore A, Rüeger S, Akiyama M, Allison MA, Alvarez M, Andersen MK, Appadurai V, Arbeeva L, Bartell E, Bhaskar S, Bielak LF, Bis JC, Bollepalli S, Bork-Jensen J, Bradfield JP, Bradford Y, Brandl C, Braund PS, Brody JA, Broeckel U, Burgdorf KS, Cade BE, Cai Q, Camarda S, Campbell A, Cañadas-Garre M, Chai JF, Chesi A, Choi SH, Christofidou P, Couture C, Cuellar-Partida G, Danning R, Degenhardt F, Delgado GE, Delitala A, Demirkan A, Deng X, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Eichelmann F, Eliasen AU, Engmann JE, Erdos MR, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Frank M, Freitag-Wolf S, Fritsche LG, Fuchsberger C, Galesloot TE, Gao Y, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, Heard-Costa N, Hemerich D, Highland… See abstract for full author list ➔ Smit RAJ, et al. Among authors: buchanan vl. Nat Med. 2025 Sep;31(9):3151-3168. doi: 10.1038/s41591-025-03827-z. Epub 2025 Jul 21. Nat Med. 2025. PMID: 40691366 Free PMC article.
Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns.
Anwar MY, Highland H, Buchanan VL, Graff M, Young K, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson CW, Aguet F, Ardlie KG, Gerszten RE, Clish CB, Lange LA, Ding J, Goodarzi MO, Chen YI, Peloso GM, Guo X, Stanislawski MA, Rotter JI, Rich SS, Justice AE, Liu CT, North K. Anwar MY, et al. Among authors: buchanan vl. Obesity (Silver Spring). 2024 Nov;32(11):2024-2034. doi: 10.1002/oby.24137. Obesity (Silver Spring). 2024. PMID: 39497627 Free PMC article.
Host genetic effects in pneumonia.
Chen HH, Shaw DM, Petty LE, Graff M, Bohlender RJ, Polikowsky HG, Zhong X, Kim D, Buchanan VL, Preuss MH, Shuey MM, Loos RJF, Huff CD, Cox NJ, Bastarache JA, Bastarache L, North KE, Below JE. Chen HH, et al. Among authors: buchanan vl. Am J Hum Genet. 2021 Jan 7;108(1):194-201. doi: 10.1016/j.ajhg.2020.12.010. Epub 2020 Dec 13. Am J Hum Genet. 2021. PMID: 33357513 Free PMC article.
Genetic underpinnings of the heterogeneous impact of obesity on lipid levels and cardiovascular disease.
Kim D, Highland HM, Smit RAJ, Hysong MR, Buchanan VL, Young KL, Zhao C, Spracklen CN, Kilpeläinen TO, Guo B, Darst BF, Cai Y, Wang Z, Lundin J, Berndt SI, Manson JE, Marouli E, Lange L, Lange E, Fornage M, Gignoux CR, Haiman CA, Rich SS, Buyske S, Loos RJF, Kooperberg C, Peters U, Avery CL, Gordon-Larsen P, Graff M, Raffield LM, North KE. Kim D, et al. Among authors: buchanan vl. Genome Med. 2025 Oct 6;17(1):113. doi: 10.1186/s13073-025-01522-9. Genome Med. 2025. PMID: 41053791 Free PMC article.
Alterations in DNA Methylation, Proteomic, and Metabolomic Profiles in African Ancestry Populations with APOL1 Risk Alleles.
Zhang X, Scadden AW, Marthi A, Buchanan VL, Qu Y, Ferrier KR, Chen BD, Graff M, Avila J, Boerwinkle E, Buyske S, Clish CB, Cruz D, Fornage M, Gerzsten RE, Gignoux CR, Glover L, Hou L, Justice AE, Kooperberg C, Kramer H, Lange L, Loos RJF, Matise T, Mychaleckyj JC, Olabisi OA, Peters U, Raffield LM, Reiner AP, Rich SS, Rotter JI, Taylor KD, Yu B, Zheng Y, North KE, Mottl AK, Highland HM, Stanislawski MA. Zhang X, et al. Among authors: buchanan vl. J Am Soc Nephrol. 2025 Apr 7;36(8):1490-1504. doi: 10.1681/ASN.0000000688. J Am Soc Nephrol. 2025. PMID: 40193202
Schwannoma of the Posterior Tibial Nerve.
Buchanan V, Rawat M. Buchanan V, et al. J Orthop Sports Phys Ther. 2020 Feb;50(2):111. doi: 10.2519/jospt.2020.9103. J Orthop Sports Phys Ther. 2020. PMID: 32005092
Strengthening Causal Inference in Exposomics Research: Application of Genetic Data and Methods.
Avery CL, Howard AG, Ballou AF, Buchanan VL, Collins JM, Downie CG, Engel SM, Graff M, Highland HM, Lee MP, Lilly AG, Lu K, Rager JE, Staley BS, North KE, Gordon-Larsen P. Avery CL, et al. Among authors: buchanan vl. Environ Health Perspect. 2022 May;130(5):55001. doi: 10.1289/EHP9098. Epub 2022 May 9. Environ Health Perspect. 2022. PMID: 35533073 Free PMC article.
Genetic determinants of metabolic biomarkers and their associations with cardiometabolic traits in Hispanic/Latino adolescents.
Kim D, Justice AE, Chittoor G, Blanco E, Burrows R, Graff M, Howard AG, Wang Y, Rohde R, Buchanan VL, Voruganti VS, Almeida M, Peralta J, Lehman DM, Curran JE, Comuzzie AG, Duggirala R, Blangero J, Albala C, Santos JL, Angel B, Lozoff B, Gahagan S, North KE. Kim D, et al. Among authors: buchanan vl. Pediatr Res. 2022 Aug;92(2):563-571. doi: 10.1038/s41390-021-01729-7. Epub 2021 Oct 13. Pediatr Res. 2022. PMID: 34645953 Free PMC article.
36 results