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Intrathecal soluble HLA-E correlates with disease activity in patients with multiple sclerosis and may cooperate with soluble HLA-G in the resolution of neuroinflammation.
Morandi F, Venturi C, Rizzo R, Castellazzi M, Baldi E, Caniatti ML, Tola MR, Granieri E, Fainardi E, Uccelli A, Pistoia V. Morandi F, et al. Among authors: caniatti ml. J Neuroimmune Pharmacol. 2013 Sep;8(4):944-55. doi: 10.1007/s11481-013-9459-3. Epub 2013 Apr 28. J Neuroimmune Pharmacol. 2013. PMID: 23625177
Serum IgG against Simian Virus 40 antigens are hampered by high levels of sHLA-G in patients affected by inflammatory neurological diseases, as multiple sclerosis.
Rizzo R, Pietrobon S, Mazzoni E, Bortolotti D, Martini F, Castellazzi M, Casetta I, Fainardi E, Di Luca D, Granieri E, Tognon M; Emilia-Romagna network for Multiple Sclerosis (ERMES) study group. Rizzo R, et al. J Transl Med. 2016 Jul 22;14(1):216. doi: 10.1186/s12967-016-0981-y. J Transl Med. 2016. PMID: 27443345 Free PMC article.
TIMP-1 resistant matrix metalloproteinase-9 is the predominant serum active isoform associated with MRI activity in patients with multiple sclerosis.
Trentini A, Manfrinato MC, Castellazzi M, Tamborino C, Roversi G, Volta CA, Baldi E, Tola MR, Granieri E, Dallocchio F, Bellini T, Fainardi E; Emilia-Romagna network for Multiple Sclerosis (ERMES) study group. Trentini A, et al. Mult Scler. 2015 Aug;21(9):1121-30. doi: 10.1177/1352458514560925. Epub 2015 Feb 6. Mult Scler. 2015. PMID: 25662349
Patient adherence to and tolerability of self-administered interferon β-1a using an electronic autoinjection device: a multicentre, open-label, phase IV study.
Lugaresi A, Florio C, Brescia-Morra V, Cottone S, Bellantonio P, Clerico M, Centonze D, Uccelli A, di Ioia M, De Luca G, Marcellusi A, Paolillo A; BRIDGE study group. Lugaresi A, et al. BMC Neurol. 2012 Mar 5;12:7. doi: 10.1186/1471-2377-12-7. BMC Neurol. 2012. PMID: 22390218 Free PMC article. Clinical Trial.