Carozza J - Search Results

Year	Number of Results
2008	1
2016	1
2017	1
2018	4
2019	2
2020	8
2021	2
2022	6
2023	5
2024	4
2025	3

1

Extracellular cGAMP is a cancer cell-produced immunotransmitter involved in radiation-induced anti-cancer immunity.

Carozza JA, Böhnert V, Nguyen KC, Skariah G, Shaw KE, Brown JA, Rafat M, von Eyben R, Graves EE, Glenn JS, Smith M, Li L. Carozza JA, et al. Nat Cancer. 2020 Feb;1(2):184-196. doi: 10.1038/s43018-020-0028-4. Epub 2020 Feb 24. Nat Cancer. 2020. PMID: 33768207 Free PMC article.

2

Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint.

Mardjuki R, Wang S, Carozza J, Zirak B, Subramanyam V, Abhiraman G, Lyu X, Goodarzi H, Li L. Mardjuki R, et al. Among authors: carozza j. Cell Rep. 2024 May 28;43(5):114209. doi: 10.1016/j.celrep.2024.114209. Epub 2024 May 14. Cell Rep. 2024. PMID: 38749434 Free article.

3

Toxicity of extracellular cGAMP and its analogs to T cells is due to SLC7A1-mediated import.

Sudaryo V, Carvalho DR, Lee JM, Carozza JA, Cao X, Cordova AF, Li L. Sudaryo V, et al. Among authors: carozza ja. bioRxiv [Preprint]. 2024 Sep 24:2024.09.21.614248. doi: 10.1101/2024.09.21.614248. bioRxiv. 2024. PMID: 39386698 Free PMC article. Preprint.

4

Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS-cGAMP-STING Pathway.

Ritchie C, Carozza JA, Li L. Ritchie C, et al. Among authors: carozza ja. Annu Rev Biochem. 2022 Jun 21;91:599-628. doi: 10.1146/annurev-biochem-040320-101629. Epub 2022 Mar 14. Annu Rev Biochem. 2022. PMID: 35287475 Review.

5

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy.

Wang S, Johnson RM, Carozza JA, Fernandez D, Scicinski J, Verity NA, Mardjuki R, Cao X, Guo Y, Papkoff J, Ray N, Li L. Wang S, et al. Among authors: carozza ja. Cell Rep Med. 2025 Sep 16;6(9):102336. doi: 10.1016/j.xcrm.2025.102336. Epub 2025 Sep 5. Cell Rep Med. 2025. PMID: 40914167 Free PMC article.

6

Discovery of VH domains that allosterically inhibit ENPP1.

Solomon PE, Bracken CJ, Carozza JA, Wang H, Young EP, Wellner A, Liu CC, Sweet-Cordero EA, Li L, Wells JA. Solomon PE, et al. Among authors: carozza ja. Nat Chem Biol. 2024 Jan;20(1):30-41. doi: 10.1038/s41589-023-01368-5. Epub 2023 Jul 3. Nat Chem Biol. 2024. PMID: 37400538 Free PMC article.

7

ENPP1 inhibitor with ultralong drug-target residence time as an innate immune checkpoint blockade cancer therapy.

Johnson RM, Wang S, Carozza JA, Fernandez D, Scicinski J, Verity NA, Mardjuki R, Cao X, Papkoff J, Ray N, Li L. Johnson RM, et al. Among authors: carozza ja. bioRxiv [Preprint]. 2025 May 22:2025.05.18.654655. doi: 10.1101/2025.05.18.654655. bioRxiv. 2025. Update in: Cell Rep Med. 2025 Sep 16;6(9):102336. doi: 10.1016/j.xcrm.2025.102336. PMID: 40475652 Free PMC article. Updated. Preprint.

8

LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP.

Lahey LJ, Mardjuki RE, Wen X, Hess GT, Ritchie C, Carozza JA, Böhnert V, Maduke M, Bassik MC, Li L. Lahey LJ, et al. Among authors: carozza ja. Mol Cell. 2020 Nov 19;80(4):578-591.e5. doi: 10.1016/j.molcel.2020.10.021. Epub 2020 Nov 9. Mol Cell. 2020. PMID: 33171122 Free article.

9

ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.

Carozza JA, Cordova AF, Brown JA, AlSaif Y, Böhnert V, Cao X, Mardjuki RE, Skariah G, Fernandez D, Li L. Carozza JA, et al. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2119189119. doi: 10.1073/pnas.2119189119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588451 Free PMC article.

10

Validation of a non-invasive prenatal test for fetal RhD, C, c, E, K and Fy^a antigens.

Alford B, Landry BP, Hou S, Bower X, Bueno AM, Chen D, Husic B, Cantonwine DE, McElrath TF, Carozza JA, Wynn J, Hoskovec J, Gray KJ. Alford B, et al. Among authors: carozza ja. Sci Rep. 2023 Aug 7;13(1):12786. doi: 10.1038/s41598-023-39283-3. Sci Rep. 2023. PMID: 37550335 Free PMC article.

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