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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1964 1
1965 5
1966 6
1967 2
1971 5
1972 1
1973 1
1977 1
1980 2
1981 1
1983 1
1985 3
1987 3
1988 2
1989 2
1990 3
1991 6
1992 4
1993 5
1994 4
1995 6
1996 7
1997 8
1998 5
1999 7
2000 8
2001 8
2002 10
2003 10
2004 17
2005 16
2006 23
2007 24
2008 29
2009 26
2010 26
2011 32
2012 33
2013 35
2014 36
2015 34
2016 43
2017 40
2018 42
2019 27
2020 26
2021 40
2022 45
2023 41
2024 46
2025 41

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753 results

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Page 1
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
Burr ML, Sparbier CE, Chan YC, Williamson JC, Woods K, Beavis PA, Lam EYN, Henderson MA, Bell CC, Stolzenburg S, Gilan O, Bloor S, Noori T, Morgens DW, Bassik MC, Neeson PJ, Behren A, Darcy PK, Dawson SJ, Voskoboinik I, Trapani JA, Cebon J, Lehner PJ, Dawson MA. Burr ML, et al. Among authors: chan yc. Nature. 2017 Sep 7;549(7670):101-105. doi: 10.1038/nature23643. Epub 2017 Aug 16. Nature. 2017. PMID: 28813417 Free PMC article.
An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer.
Burr ML, Sparbier CE, Chan KL, Chan YC, Kersbergen A, Lam EYN, Azidis-Yates E, Vassiliadis D, Bell CC, Gilan O, Jackson S, Tan L, Wong SQ, Hollizeck S, Michalak EM, Siddle HV, McCabe MT, Prinjha RK, Guerra GR, Solomon BJ, Sandhu S, Dawson SJ, Beavis PA, Tothill RW, Cullinane C, Lehner PJ, Sutherland KD, Dawson MA. Burr ML, et al. Among authors: chan yc. Cancer Cell. 2019 Oct 14;36(4):385-401.e8. doi: 10.1016/j.ccell.2019.08.008. Epub 2019 Sep 26. Cancer Cell. 2019. PMID: 31564637 Free PMC article.
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.
Sparbier CE, Gillespie A, Gomez J, Kumari N, Motazedian A, Chan KL, Bell CC, Gilan O, Chan YC, Popp S, Gough DJ, Eckersley-Maslin MA, Dawson SJ, Lehner PJ, Sutherland KD, Ernst P, McGeehan GM, Lam EYN, Burr ML, Dawson MA. Sparbier CE, et al. Among authors: chan yc. Nat Cell Biol. 2023 Feb;25(2):258-272. doi: 10.1038/s41556-022-01056-x. Epub 2023 Jan 12. Nat Cell Biol. 2023. PMID: 36635503 Free PMC article.
Non-genetic determinants of malignant clonal fitness at single-cell resolution.
Fennell KA, Vassiliadis D, Lam EYN, Martelotto LG, Balic JJ, Hollizeck S, Weber TS, Semple T, Wang Q, Miles DC, MacPherson L, Chan YC, Guirguis AA, Kats LM, Wong ES, Dawson SJ, Naik SH, Dawson MA. Fennell KA, et al. Among authors: chan yc. Nature. 2022 Jan;601(7891):125-131. doi: 10.1038/s41586-021-04206-7. Epub 2021 Dec 8. Nature. 2022. PMID: 34880496
Metronidazole-Induced Mania.
Chan YC. Chan YC. Prim Care Companion CNS Disord. 2023 Jun 22;25(3):22cr03408. doi: 10.4088/PCC.22cr03408. Prim Care Companion CNS Disord. 2023. PMID: 37347677 Free article. No abstract available.
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses.
Chan KL, Gomez J, Cardinez C, Kumari N, Sparbier CE, Lam EYN, Yeung MM, Garciaz S, Kuzich JA, Ong DM, Brown FC, Chan YC, Vassiliadis D, Wainwright EN, Motazedian A, Gillespie A, Fennell KA, Lai J, House IG, Macpherson L, Ang CS, Dawson SJ, Beavis PA, Wei AH, Burr ML, Dawson MA. Chan KL, et al. Among authors: chan yc. Cancer Cell. 2022 Oct 10;40(10):1190-1206.e9. doi: 10.1016/j.ccell.2022.09.007. Epub 2022 Sep 29. Cancer Cell. 2022. PMID: 36179686 Free PMC article.
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.
Guirguis AA, Ofir-Rosenfeld Y, Knezevic K, Blackaby W, Hardick D, Chan YC, Motazedian A, Gillespie A, Vassiliadis D, Lam EYN, Tran K, Andrews B, Harbour ME, Vasiliauskaite L, Saunders CJ, Tsagkogeorga G, Azevedo A, Obacz J, Pilka ES, Carkill M, MacPherson L, Wainwright EN, Liddicoat B, Blyth BJ, Albertella MR, Rausch O, Dawson MA. Guirguis AA, et al. Among authors: chan yc. Cancer Discov. 2023 Oct 5;13(10):2228-2247. doi: 10.1158/2159-8290.CD-23-0007. Cancer Discov. 2023. PMID: 37548590
Reply.
Li HL, Chan YC, Cheng SW. Li HL, et al. Among authors: chan yc. J Vasc Surg Venous Lymphat Disord. 2024 May;12(3):101821. doi: 10.1016/j.jvsv.2024.101821. J Vasc Surg Venous Lymphat Disord. 2024. PMID: 38631805 Free PMC article. No abstract available.
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Gordon SJV, Perner F, MacPherson L, Wenge DV, Bourgeois W, Fennell K, Klaus T, Petrovic J, Horvath J, Cao J, Lapek J, Uryu S, White J, Lam EYN, Mu XJ, Chan YC, Gillespie A, Blyth B, Camerino MA, Bozikis YE, Holze H, Knezevic K, Balic J, Stupple PA, Street IP, Monahan BJ, Sharma S, Wainwright EN, Vassiliadis D, Paul TA, Armstrong SA, Dawson MA. Gordon SJV, et al. Among authors: chan yc. bioRxiv [Preprint]. 2024 Dec 12:2024.12.11.627663. doi: 10.1101/2024.12.11.627663. bioRxiv. 2024. Update in: Cancer Discov. 2025 Oct 6;15(10):2117-2138. doi: 10.1158/2159-8290.CD-24-1517. PMID: 39713447 Free PMC article. Updated. Preprint.
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia.
Gilan O, Talarmain L, Bell CC, Neville D, Knezevic K, Ferguson DT, Boudes M, Chan YC, Davidovich C, Lam EYN, Dawson MA. Gilan O, et al. Among authors: chan yc. Nat Struct Mol Biol. 2023 Oct;30(10):1592-1606. doi: 10.1038/s41594-023-01087-4. Epub 2023 Sep 7. Nat Struct Mol Biol. 2023. PMID: 37679565
753 results