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A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants.
Liu X, Ng WH, Zusinaite E, Freitas J, Taylor A, Yerragunta V, Aavula SM, Gorriparthi S, Ponsekaran S, Bonda RL, Mani P, Nimmagadda SV, Wang S, Lello LS, Zaid A, Dua U, Taft-Benz SA, Anderson E, Baxter VK, Sarkar S, Ling ZL, Ashhurst TM, Cheng SMS, Pattnaik P, Kanakasapapathy AK, Baric RS, Burt FJ, Peiris M, Heise MT, King NJC, Merits A, Lingala R, Mahalingam S. Liu X, et al. Among authors: cheng sms. Nat Commun. 2024 Aug 26;15(1):7225. doi: 10.1038/s41467-024-51535-y. Nat Commun. 2024. PMID: 39187479 Free PMC article.
SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years.
Rowntree LC, Audsley J, Allen LF, McQuilten HA, Hagen RR, Chaurasia P, Petersen J, Littler DR, Tan HX, Murdiyarso L, Habel JR, Foo IJH, Zhang W, Ten Berge ERV, Ganesh H, Kaewpreedee P, Lee KWK, Cheng SMS, Kwok JSY, Jayasinghe D, Gras S, Juno JA, Wheatley AK, Kent SJ, Rossjohn J, Cheng AC, Kotsimbos TC, Trubiano JA, Holmes NE, Pang Chan KK, Hui DSC, Peiris M, Poon LLM, Lewin SR, Doherty PC, Thevarajan I, Valkenburg SA, Kedzierska K, Nguyen THO. Rowntree LC, et al. Among authors: cheng sms. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2411428121. doi: 10.1073/pnas.2411428121. Epub 2024 Sep 16. Proc Natl Acad Sci U S A. 2024. PMID: 39284068 Free PMC article.
A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories.
Brangel P, Tureli S, Mühlemann B, Liechti N, Zysset D, Engler O, Hunger-Glaser I, Ghiga I, Mattiuzzo G, Eckerle I, Bekliz M, Rössler A, Schmitt MM, Knabl L, Kimpel J, Tort LFL, de Araujo MF, de Oliveira ACA, Caetano BC, Siqueira MM, Budt M, Gensch JM, Wolff T, Hassan T, Selvaraj FA, Hermanus T, Kgagudi P, Crowther C, Richardson SI, Bhiman JN, Moore PL, Cheng SMS, Li JKC, Poon LLM, Peiris M, Corman VM, Drosten C, Lai L, Hunsawong T, Rungrojcharoenkit K, Lohachanakul J, Sigal A, Khan K, Thiel V, Barut GT, Ebert N, Mykytyn AZ, Owusu Donkor I, Aboagye JO, Nartey PA, Van Kerkhove MD, Cunningham J, Haagmans BL, Suthar MS, Smith D, Subissi L. Brangel P, et al. Among authors: cheng sms. Viruses. 2024 Dec 18;16(12):1936. doi: 10.3390/v16121936. Viruses. 2024. PMID: 39772242 Free PMC article.
Neutralizing antibody titres in SARS-CoV-2 infections.
Lau EHY, Tsang OTY, Hui DSC, Kwan MYW, Chan WH, Chiu SS, Ko RLW, Chan KH, Cheng SMS, Perera RAPM, Cowling BJ, Poon LLM, Peiris M. Lau EHY, et al. Among authors: cheng sms. Nat Commun. 2021 Jan 4;12(1):63. doi: 10.1038/s41467-020-20247-4. Nat Commun. 2021. PMID: 33397909 Free PMC article.
HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes.
Rowntree LC, Allen LF, Hagen RR, McQuilten HA, Quadeer AA, Chaurasia P, Kaewpreedee P, Lee KWK, Cohen CA, Petersen J, Littler DR, Habel JR, Zhang W, Cheng SMS, Chan KKP, Kwok JSY, Leung KSM, Wu JT, Lee CK, Davies J, Pannaraj PS, Kaity Allen E, Thomas PG, Tosif S, Crawford NW, Lappas M, Thevarajan I, Lewin SR, Kent SJ, Juno JA, Bond KA, Williamson DA, Holmes NE, Smibert OC, Gordon CL, Trubiano JA, Kotsimbos TC, Cheng AC, Efstathiou C, Turtle L, Thwaites RS, Brightling CE; PHOSP-COVID Collaborative Group; Rossjohn J, McKay MR, Tian J, Liu WJ, Gao GF, Xu J, Sonehara K, Ishii KJ, Namkoong H, Okada Y, Peiris M, Hui DSC, Poon LLM, Doherty PC, Nguyen THO, Valkenburg SA, Kedzierska K. Rowntree LC, et al. Among authors: cheng sms. Proc Natl Acad Sci U S A. 2025 Sep 9;122(36):e2503145122. doi: 10.1073/pnas.2503145122. Epub 2025 Sep 2. Proc Natl Acad Sci U S A. 2025. PMID: 40892914 Free PMC article.
Resurgence of Omicron BA.2 in SARS-CoV-2 infection-naive Hong Kong.
Xie R, Edwards KM, Adam DC, Leung KSM, Tsang TK, Gurung S, Xiong W, Wei X, Ng DYM, Liu GYZ, Krishnan P, Chang LDJ, Cheng SMS, Gu H, Siu GKH, Wu JT, Leung GM, Peiris M, Cowling BJ, Poon LLM, Dhanasekaran V. Xie R, et al. Among authors: cheng sms. Nat Commun. 2023 Apr 27;14(1):2422. doi: 10.1038/s41467-023-38201-5. Nat Commun. 2023. PMID: 37105966 Free PMC article.
57 results