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Showing results for cheng long l
Search for Ching-Long L instead (1 results)
Metal-ion-chelating phenylalanine nanostructures reverse immune dysfunction and sensitize breast tumour to immune checkpoint blockade.
Tan M, Cao G, Wang R, Cheng L, Huang W, Yin Y, Ma H, Ho SH, Wang Z, Zhu M, Ran H, Nie G, Wang H. Tan M, et al. Among authors: cheng l. Nat Nanotechnol. 2024 Dec;19(12):1903-1913. doi: 10.1038/s41565-024-01758-3. Epub 2024 Aug 26. Nat Nanotechnol. 2024. PMID: 39187583
Here we demonstrate that metal-ion-chelating L-phenylalanine nanostructures synergize with short-term starvation (STS) to remodel the immunosuppressive microenvironment of breast and colorectal tumours. ...This study demonstrates the potential role of metal-ion-chelating …
Here we demonstrate that metal-ion-chelating L-phenylalanine nanostructures synergize with short-term starvation (STS) to remodel the …
α-Linolenic acid promotes testosterone synthesis by improving mitochondrial function in primary rooster Leydig cells.
Chang X, Li D, Guo Y, Sheng X, Wang X, Xing K, Xiao L, Lv X, Long C, Qi X. Chang X, et al. Among authors: long c. Theriogenology. 2025 Jan 15;232:9-19. doi: 10.1016/j.theriogenology.2024.10.026. Epub 2024 Nov 1. Theriogenology. 2025. PMID: 39504870
METHODS: Purified primary Leydig cells isolated from 65-week-old roosters were purified and treated with different concentrations of ALA treatments: (0 mum/L [control], solvent control group (DMSO), 20 muM/L, 40 muM/L, and 80 muM/L) and cell counting-8 …
METHODS: Purified primary Leydig cells isolated from 65-week-old roosters were purified and treated with different concentrations of ALA tre …
Chemical and nutritional characteristics, and microbial degradation of rapeseed meal recalcitrant carbohydrates: A review.
Long C, Qi XL, Venema K. Long C, et al. Front Nutr. 2022 Sep 28;9:948302. doi: 10.3389/fnut.2022.948302. eCollection 2022. Front Nutr. 2022. PMID: 36245487 Free PMC article. Review.
Glycoside hydrolases including in the degradation of RSM carbohydrates are alpha-L-Arabinofuranosidases (EC 3.2.1.55), endo-alpha-1,5-L-arabinanases (EC 3.2.1.99), Endo-1,4-beta-mannanase (EC 3.2.1.78), beta-mannosidase (EC 3.2.1.25), alpha-galactosidase (EC 3.2.1.2 …
Glycoside hydrolases including in the degradation of RSM carbohydrates are alpha-L-Arabinofuranosidases (EC 3.2.1.55), endo-alpha-1,5 …
Comparison of Herbal Medicines Used for Women's Menstruation Diseases in Different Areas of the World.
Jiao M, Liu X, Ren Y, Wang Y, Cheng L, Liang Y, Li Y, Zhang T, Wang W, Mei Z. Jiao M, et al. Among authors: cheng l. Front Pharmacol. 2022 Feb 4;12:751207. doi: 10.3389/fphar.2021.751207. eCollection 2021. Front Pharmacol. 2022. PMID: 35185533 Free PMC article. Review.
Zingiber officinale Roscoe (Ginger), Ruta graveolens L. (Common rue), Angelica sinensis (Oliv.) Diels (Angelica sinensis), Foeniculum vulgare Mill (Fennel), Catharanthus roseus (L.) ...
Zingiber officinale Roscoe (Ginger), Ruta graveolens L. (Common rue), Angelica sinensis (Oliv.) Diels (Angelica sinensis), Foeniculum …
α-Linolenic acid-regulated testosterone biosynthesis via activation of the JNK-SF-1 signaling pathway in primary rooster Leydig cells.
Zhao ZX, Shang MY, Long C, Yao XJ, Gao XB, Guo Y, Sheng XH, Wang XG, Xing K, Xiao LF, Qi XL. Zhao ZX, et al. Among authors: long c. Theriogenology. 2023 Oct 1;209:170-177. doi: 10.1016/j.theriogenology.2023.06.030. Epub 2023 Jun 24. Theriogenology. 2023. PMID: 37393747
METHODS: Primary rooster Leydig cells were treated with ALA (0, 20, 40, or 80 mumol/L) or pretreated with a p38 inhibitor (50 mumol/L), a c-Jun NH2-terminal kinase (JNK) inhibitor (20 mumol/L), or an extracellular signal-regulated kinase (ERK) inhibitor (20 m …
METHODS: Primary rooster Leydig cells were treated with ALA (0, 20, 40, or 80 mumol/L) or pretreated with a p38 inhibitor (50 mumol/ …
Establishment of a mathematical prediction model for voriconazole stable maintenance dose: a prospective study.
Zhou L, Li M, Li H, Guo Z, Gao Y, Zhang H, Qin F, Sang Z, Xing Q, Cheng L, Cao W. Zhou L, et al. Among authors: cheng l. Front Cell Infect Microbiol. 2023 Jul 26;13:1157944. doi: 10.3389/fcimb.2023.1157944. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37565064 Free PMC article. Clinical Trial.

BACKGROUND: In patients with invasive fungal infection (IFI), the steady-state serum trough concentration (C (min)) of voriconazole (VCZ) is highly variable and can lead to treatment failure (C (min) < 0.5 mg/L) and toxicity (C (min) 5.0 mg/L). However, It remain

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BACKGROUND: In patients with invasive fungal infection (IFI), the steady-state serum trough concentration (C (min)) of voriconazole (VCZ) is …
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.
An Y, Dai H, Duan Y, Cheng L, Shi L, He C, Wang C, Lv Y, Li H, Zhang H, Huang Y, Fu W, Sun W, Zhao B. An Y, et al. Among authors: cheng l. Chin Med. 2023 May 5;18(1):49. doi: 10.1186/s13020-023-00717-9. Chin Med. 2023. PMID: 37147692 Free PMC article.

METHODS: Thirty-two SPF-grade SD rats were raised as donor rats, and divided into control, type 2 diabetes mellitus (T2DM, fasting blood glucose 11.1 mmol/L), and Non-T2DM (fasting blood glucose < 11.1 mmol/L) groups. Feces were collected and prepared as fecal ba

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METHODS: Thirty-two SPF-grade SD rats were raised as donor rats, and divided into control, type 2 diabetes mellitus (T2DM, fasting blood glu …
Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia.
Xie Z, Zhang M, Song Q, Cheng L, Zhang X, Song G, Sun X, Gu M, Zhou C, Zhang Y, Zhu K, Yin J, Chen X, Li J, Nan F. Xie Z, et al. Among authors: cheng l. Acta Pharm Sin B. 2023 Feb;13(2):739-753. doi: 10.1016/j.apsb.2022.06.011. Epub 2022 Jun 18. Acta Pharm Sin B. 2023. PMID: 36873173 Free PMC article.
In this study, we developed the small molecule 326E with an enedioic acid structural moiety as a novel ACLY inhibitor, and its CoA-conjugated form 326E-CoA inhibited ACLY activity with an IC(50) = 5.31 1.2 mumol/L in vitro. 326E treatment reduced de novo lipogenesis, and i …
In this study, we developed the small molecule 326E with an enedioic acid structural moiety as a novel ACLY inhibitor, and its CoA-conjugate …
D-dimer for assessment of treatment response, and survival to drug-eluting beads transarterial chemoembolization in hepatocellular carcinoma.
Duan Y, Hou X, Guo J, Li H, Cai L, Cheng L, Zhao W, Shao X, Du H, Diao Z, Li C. Duan Y, et al. Among authors: cheng l. Clin Res Hepatol Gastroenterol. 2023 Apr;47(4):102096. doi: 10.1016/j.clinre.2023.102096. Epub 2023 Feb 17. Clin Res Hepatol Gastroenterol. 2023. PMID: 36801385 Free article.
Then, patients were classified by the median value of D-dimer, and it was observed that patients with D-dimer >0.7 mg/L achieved a lower complete response rate (12.0% vs. 46.2%, P = 0.007) but a similar objective response rate (84.0% vs. 84.6%, P = 1.000) compared to th …
Then, patients were classified by the median value of D-dimer, and it was observed that patients with D-dimer >0.7 mg/L achieved a …
Biocytin-Labeling in Whole-Cell Recording: Electrophysiological and Morphological Properties of Pyramidal Neurons in CYLD-Deficient Mice.
Tan S, Mo X, Qin H, Dong B, Zhou J, Long C, Yang L. Tan S, et al. Among authors: long c. Molecules. 2023 May 15;28(10):4092. doi: 10.3390/molecules28104092. Molecules. 2023. PMID: 37241833 Free PMC article.
Biocytin, a chemical compound that is an amide formed from the vitamin biotin and the amino acid L-lysine, has been used as a histological dye to stain nerve cells. Electrophysiological activity and morphology are two key characteristics of neurons, but revealing both the …
Biocytin, a chemical compound that is an amide formed from the vitamin biotin and the amino acid L-lysine, has been used as a histolo …
46 results