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16,377 results

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Page 1
Showing results for chiral p
Search for Chirag P instead (1 results)
Chiral and Regenerable NAD(P)H Models Enabled Biomimetic Asymmetric Reduction: Design, Synthesis, Scope, and Mechanistic Studies.
Wang J, Zhao ZB, Zhao Y, Luo G, Zhu ZH, Luo Y, Zhou YG. Wang J, et al. J Org Chem. 2020 Feb 21;85(4):2355-2368. doi: 10.1021/acs.joc.9b03054. Epub 2020 Jan 10. J Org Chem. 2020. PMID: 31886670
However, the development of a general and new-generation biomimetic asymmetric reduction is still a long-term challenge. Herein, a series of chiral and regenerable NAD(P)H models with central, axial, and planar chiralities have been designed and applied in bi …
However, the development of a general and new-generation biomimetic asymmetric reduction is still a long-term challenge. Herein, a series of …
Axially chiral N-alkyl-N-cinnamoyl amide type P,olefin ligands for Pd-catalyzed reactions.
Mino T, Takaya K, Koki K, Akimoto N, Yoshida Y, Kasashima Y, Sakamoto M. Mino T, et al. Org Biomol Chem. 2023 Mar 29;21(13):2775-2778. doi: 10.1039/d3ob00224a. Org Biomol Chem. 2023. PMID: 36920143
We synthesized N-alkyl-N-cinnamoyl amide type phosphine-olefin compounds 1 and found axial chirality in a C(aryl)-N(amide) bond in compounds 1 by HPLC analysis using a chiral stationary phase column. We successfully obtained enantiomeric isomers of 1 and demonstrate …
We synthesized N-alkyl-N-cinnamoyl amide type phosphine-olefin compounds 1 and found axial chirality in a C(aryl)-N(amide) bond in co …
Artificial Chiral Probes and Bioapplications.
Hao C, Xu L, Kuang H, Xu C. Hao C, et al. Adv Mater. 2020 Oct;32(41):e1802075. doi: 10.1002/adma.201802075. Epub 2019 Jan 17. Adv Mater. 2020. PMID: 30656745 Review.
The development of artificial chiral architectures, especially chiral inorganic nanostructures, has greatly promoted research into chirality in nanoscience. The nanoscale chirality of artificial chiral nanostructures offers many new application …
The development of artificial chiral architectures, especially chiral inorganic nanostructures, has greatly promoted research …
Cinnamoyl amide type chiral P,olefin ligands for Pd-catalyzed reactions.
Mino T, Fujisawa Y, Yoshida S, Hirama M, Akiyama T, Saito R, Yoshida Y, Kasashima Y, Sakamoto M. Mino T, et al. Org Biomol Chem. 2021 Dec 8;19(47):10385-10389. doi: 10.1039/d1ob02086b. Org Biomol Chem. 2021. PMID: 34821903
We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and demonstrated Pd-catalyzed asymmetric allylic substitution reactions of indoles using (S,aS)-4d as a chiral ligand with high enantiosel …
We synthesized cinnamoyl amide type chiral P,olefin ligand (S)-4. We successfully obtained separable diastereomers of 4d and d …
Chiral Supramolecular Assemblies: Controllable Construction and Biological Activity.
He S, Jiang Z, Dou X, Gao L, Feng C. He S, et al. Chempluschem. 2023 Jul;88(7):e202300226. doi: 10.1002/cplu.202300226. Chempluschem. 2023. PMID: 37438864 Review.
This review discusses recent advances in chiral supramolecular assembly, including the precise construction and regulation of assembled chiral nanostructures with tunable chirality. ...This review not only contributes to further understanding of the importanc …
This review discusses recent advances in chiral supramolecular assembly, including the precise construction and regulation of assembl …
Chiral metallosupramolecular architectures.
Chen LJ, Yang HB, Shionoya M. Chen LJ, et al. Chem Soc Rev. 2017 May 9;46(9):2555-2576. doi: 10.1039/c7cs00173h. Chem Soc Rev. 2017. PMID: 28452389 Review.
Over the past few decades, supramolecular chirality in discrete metallosupramolecular architectures has received considerable attention. ...Although chirality can be introduced prior to, during or even after the coordination self-assembly process, this review puts m …
Over the past few decades, supramolecular chirality in discrete metallosupramolecular architectures has received considerable attenti …
Chiral Induced Spin Selectivity and Its Implications for Biological Functions.
Naaman R, Paltiel Y, Waldeck DH. Naaman R, et al. Annu Rev Biophys. 2022 May 9;51:99-114. doi: 10.1146/annurev-biophys-083021-070400. Epub 2021 Dec 21. Annu Rev Biophys. 2022. PMID: 34932912 Review.
Chirality in life has been preserved throughout evolution. It has been assumed that the main function of chirality is its contribution to structural properties. In the past two decades, however, it has been established that chiral molecules possess unique ele
Chirality in life has been preserved throughout evolution. It has been assumed that the main function of chirality is its cont
Unimolecular Chiral Stepping Inversion Machine.
Sun Y, Liu L, Jiang L, Chen Y, Zhang H, Xu X, Liu Y. Sun Y, et al. J Am Chem Soc. 2023 Aug 2;145(30):16711-16717. doi: 10.1021/jacs.3c04430. Epub 2023 Jul 24. J Am Chem Soc. 2023. PMID: 37486147
Compared with the longer aliphatic linker PT5, PT3 with a shorter aliphatic linker shows chiral stepping inversion, achieving chiral inversion under a two-electron redox potential. ...This work demonstrates unimolecular chiral stepping inversion, providing a …
Compared with the longer aliphatic linker PT5, PT3 with a shorter aliphatic linker shows chiral stepping inversion, achieving chir
Rhodium-Catalyzed Asymmetric Access to P-Chiral Triarylphosphine Oxides via Insertion of PH Bonds into Diazonaphthoquinones.
Kang Y, Shi Y, Huang G, Li X. Kang Y, et al. Angew Chem Int Ed Engl. 2025 Jul 28;64(31):e202500436. doi: 10.1002/anie.202500436. Epub 2025 Jun 30. Angew Chem Int Ed Engl. 2025. PMID: 40050247
While significant progress has been made in the enantioselective insertion of carbenes into heteroatom-hydrogen bonds, this chemistry is restricted to the construction of carbon-based chirality. The asymmetric insertion of carbenes into PH that delivers P-chiral
While significant progress has been made in the enantioselective insertion of carbenes into heteroatom-hydrogen bonds, this chemistry is res …
Access to P- and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cp(x) Ir(III) -Catalyzed C-H Arylations.
Jang YS, Woźniak Ł, Pedroni J, Cramer N. Jang YS, et al. Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12901-12905. doi: 10.1002/anie.201807749. Epub 2018 Aug 29. Angew Chem Int Ed Engl. 2018. PMID: 30044513
An enantioselective C-H arylation of phosphine oxides with o-quinone diazides catalyzed by an iridium(III) complex bearing an atropchiral cyclopentadienyl (Cp(x) ) ligand and phthaloyl tert-leucine as co-catalyst is reported. The method allows access to a) P-chiral
An enantioselective C-H arylation of phosphine oxides with o-quinone diazides catalyzed by an iridium(III) complex bearing an atropchiral cy …
16,377 results
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