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Year Number of Results
1993 1
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1996 2
1997 1
1998 1
1999 2
2000 2
2001 1
2002 1
2004 6
2005 3
2006 6
2007 1
2008 4
2009 6
2010 7
2011 5
2012 6
2013 10
2014 16
2015 8
2016 8
2017 14
2018 10
2019 14
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2025 35

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229 results

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Page 1
Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.
Edwards NC, Lao PJ, Alshikho MJ, Ericsson OM, Rizvi B, Petersen ME, O'Bryant S, Aguilar LF, Simoes S, Mapstone M, Tudorascu DL, Janelidze S, Hansson O, Handen BL, Christian BT, Lee JH, Lai F, Rosas HD, Zaman S, Lott IT, Yassa MA; Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC-DS) Investigators; Gutierrez J, Wilcock DM, Head E, Brickman AM. Edwards NC, et al. Among authors: christian bt. Brain Commun. 2024 Sep 25;6(5):fcae331. doi: 10.1093/braincomms/fcae331. eCollection 2024. Brain Commun. 2024. PMID: 39403075 Free PMC article.
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys.
Tao Y, Vermilyea SC, Zammit M, Lu J, Olsen M, Metzger JM, Yao L, Chen Y, Phillips S, Holden JE, Bondarenko V, Block WF, Barnhart TE, Schultz-Darken N, Brunner K, Simmons H, Christian BT, Emborg ME, Zhang SC. Tao Y, et al. Among authors: christian bt. Nat Med. 2021 Apr;27(4):632-639. doi: 10.1038/s41591-021-01257-1. Epub 2021 Mar 1. Nat Med. 2021. PMID: 33649496 Free PMC article.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Among authors: christian bt. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography.
Coughlan GT, Betthauser TJ, Boyle R, Koscik RL, Klinger HM, Chibnik LB, Jonaitis EM, Yau WW, Wenzel A, Christian BT, Gleason CE, Saelzler UG, Properzi MJ, Schultz AP, Hanseeuw BJ, Manson JE, Rentz DM, Johnson KA, Sperling R, Johnson SC, Buckley RF. Coughlan GT, et al. Among authors: christian bt. JAMA Neurol. 2023 May 1;80(5):462-473. doi: 10.1001/jamaneurol.2023.0455. JAMA Neurol. 2023. PMID: 37010830 Free PMC article.
Characterizing the emergence of amyloid and tau burden in Down syndrome.
Zammit MD, Betthauser TJ, McVea AK, Laymon CM, Tudorascu DL, Johnson SC, Hartley SL, Converse AK, Minhas DS, Zaman SH, Ances BM, Stone CK, Mathis CA, Cohen AD, Klunk WE, Handen BL, Christian BT; Alzheimer's Biomarker Consortium - Down Syndrome. Zammit MD, et al. Among authors: christian bt. Alzheimers Dement. 2024 Jan;20(1):388-398. doi: 10.1002/alz.13444. Epub 2023 Aug 29. Alzheimers Dement. 2024. PMID: 37641577 Free PMC article.
CSF total tau as a proxy of synaptic degeneration.
Soares C, Bellaver B, Ferreira PCL, Povala G, Schaffer Aguzzoli C, Ferrari-Souza JP, Zalzale H, Lussier FZ, Rohden F, Abbas S, Bauer-Negrini G, Teixeira Leffa D, Benedet AL, Langhough R, Betthauser TJ, Christian BT, Wilson RE, L Tudorascu D, Rosa-Neto P, Karikari TK, Zetterberg H, Blennow K, Zimmer ER, Johnson SC, Pascoal TA. Soares C, et al. Among authors: christian bt. Nat Commun. 2025 Aug 29;16(1):8076. doi: 10.1038/s41467-025-63545-5. Nat Commun. 2025. PMID: 40883301 Free PMC article.
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex.
Ossenkoppele R, Coomans EM, Apostolova LG, Baker SL, Barthel H, Beach TG, Benzinger TLS, Betthauser T, Bischof GN, Bottlaender M, Bourgeat P, den Braber A, Brendel M, Brickman AM, Cash DM, Carrillo MC, Coath W, Christian BT, Dickerson BC, Dore V, Drzezga A, Feizpour A, van der Flier WM, Franzmeier N, Frisoni GB, Garibotto V, van de Giessen E, Domingo-Gispert J, Gnoerich J, Gu Y, Guan Y, Hanseeuw BJ, Harrison TM, Jack CR, Jaeger E, Jagust WJ, Jansen WJ, La Joie R, Johnson KA, Johnson SC, Kennedy IA, Kim JP, van Laere K, Lagarde J, Lao P, Luchsinger JA, Kern S, Kreisl WC, Malotaux V, Malpetti M, Manly JJ, Mao X, Mattsson-Carlgren N; Mayo Clinic Study on Aging; Messerschmidt K, Minguillon C, Mormino EM, O'Brien JT, Palmqvist S, Peretti DE, Petersen RC, Pijnenburg YAL, Pontecorvo MJ, Poirier J; PREVENT-AD Research Group; Rabinovici GD, Rahmouni N, Risacher SL, Rosa-Neto P, Rosen H, Rowe CC, Rowe JB, Rullmann M, Salman Y, Sarazin M, Saykin AJ, Schneider JA, Schöll M, Schott JM, Seo SW, Serrano GE, Shcherbinin S, Shekari M, Skoog I, Smith R, Sperling RA, Spruyt L, Stomrud E, Strandberg O, Therriault J, Xie F, Vandenberghe R, Villemagne VL, Villeneuve S, Visser PJ, Vossler H, Youn… See abstract for full author list ➔ Ossenkoppele R, et al. Among authors: christian bt. Nat Neurosci. 2025 Aug;28(8):1610-1621. doi: 10.1038/s41593-025-02000-6. Epub 2025 Jul 16. Nat Neurosci. 2025. PMID: 40670684 Free PMC article.
Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Christian BT, Hartley SL; Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS). Schworer EK, et al. Among authors: christian bt. Lancet Neurol. 2024 Dec;23(12):1214-1224. doi: 10.1016/S1474-4422(24)00426-5. Lancet Neurol. 2024. PMID: 39577922
Plasma GFAP for populational enrichment of clinical trials in preclinical Alzheimer's disease.
Bellaver B, Povala G, Ferreira PCL, Bauer-Negrini G, Lussier FZ, Leffa DT, Ferrari-Souza JP, Rodrigues MS, Amaral L, Oliveira MS, Soares C, Rocha A, Saha P, Rahmouni N, Macedo A, Tissot C, Therriault J, Servaes S, Klostranec J, Montembeault M, Benedet AL, Ashton NJ, Koscik RL, Betthauser TJ, Christian BT, Wilson R, Triana-Baltzer G, Vitali P, Gauthier S, Zetterberg H, Blennow K, Karikari TK, Tudorascu D, Zimmer ER, Johnson S, Rosa-Neto P, Pascoal TA. Bellaver B, et al. Among authors: christian bt. Alzheimers Dement. 2025 May;21(5):e70209. doi: 10.1002/alz.70209. Alzheimers Dement. 2025. PMID: 40346617 Free PMC article.
The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome.
Xicota L, Dang LT, Lee A, Krinsky-McHale S, Pang D, Melilli L, O'Bryant S, Henson RL, Laymon C, Lai F, Rosas HD, Ances B, Lott I, Hom C, Christian B, Hartley S, Zaman S, Head E, Mapstone M, Jin Z, Silverman W, Schupf N, Handen B, Lee JH; Alzheimer's Biomarker Consortium – Down Syndrome (ABC-DS). Xicota L, et al. EBioMedicine. 2024 Dec;110:105433. doi: 10.1016/j.ebiom.2024.105433. Epub 2024 Nov 4. EBioMedicine. 2024. PMID: 39500037 Free PMC article.
229 results