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1842 1
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1885 1
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1894 1
1895 1
1898 1
1899 2
1900 1
1901 1
1905 1
1907 2
1908 3
1909 1
1910 4
1911 2
1912 4
1913 5
1914 6
1915 5
1916 7
1917 13
1918 11
1919 11
1920 7
1921 8
1922 5
1923 6
1924 3
1925 8
1926 8
1927 10
1928 5
1929 4
1930 4
1931 3
1932 5
1933 9
1934 3
1935 2
1936 6
1937 6
1938 6
1939 1
1940 5
1941 2
1942 3
1943 5
1944 2
1945 9
1946 11
1947 13
1948 27
1949 35
1950 29
1951 35
1952 29
1953 46
1954 45
1955 59
1956 62
1957 80
1958 71
1959 88
1960 73
1961 70
1962 80
1963 89
1964 97
1965 100
1966 122
1967 119
1968 166
1969 150
1970 180
1971 177
1972 192
1973 211
1974 265
1975 1454
1976 1635
1977 1540
1978 1603
1979 1774
1980 1896
1981 2003
1982 2181
1983 2711
1984 2957
1985 3068
1986 3185
1987 3492
1988 3598
1989 4469
1990 4787
1991 4934
1992 5024
1993 5388
1994 5697
1995 6060
1996 6471
1997 6620
1998 7097
1999 7585
2000 8355
2001 8821
2002 9307
2003 10145
2004 10951
2005 11972
2006 13256
2007 13642
2008 14726
2009 15426
2010 16933
2011 18348
2012 20203
2013 21143
2014 22162
2015 22906
2016 23756
2017 24606
2018 25368
2019 26668
2020 30977
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568,984 results

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Page 1
Showing results for clear i
Search for Cleer I instead (2 results)
Whole-mouse clearing and imaging at the cellular level with vDISCO.
Cai R, Kolabas ZI, Pan C, Mai H, Zhao S, Kaltenecker D, Voigt FF, Molbay M, Ohn TL, Vincke C, Todorov MI, Helmchen F, Van Ginderachter JA, Ertürk A. Cai R, et al. Nat Protoc. 2023 Apr;18(4):1197-1242. doi: 10.1038/s41596-022-00788-2. Epub 2023 Jan 25. Nat Protoc. 2023. PMID: 36697871 Review.
Homeostatic and pathological phenomena often affect multiple organs across the whole organism. Tissue clearing methods, together with recent advances in microscopy, have made holistic examinations of biological samples feasible. Here, we report the detailed protocol for na …
Homeostatic and pathological phenomena often affect multiple organs across the whole organism. Tissue clearing methods, together with …
Three-dimensional imaging of solvent-cleared organs using 3DISCO.
Ertürk A, Becker K, Jährling N, Mauch CP, Hojer CD, Egen JG, Hellal F, Bradke F, Sheng M, Dodt HU. Ertürk A, et al. Nat Protoc. 2012 Nov;7(11):1983-95. doi: 10.1038/nprot.2012.119. Epub 2012 Oct 11. Nat Protoc. 2012. PMID: 23060243
The introduction of methods to achieve the optical clearing and subsequent light-sheet laser scanning of entire transparent organs without sectioning represents a major advance in the field. We recently developed a highly reproducible and versatile clearing procedur …
The introduction of methods to achieve the optical clearing and subsequent light-sheet laser scanning of entire transparent organs wi …
Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging.
Susaki EA, Tainaka K, Perrin D, Yukinaga H, Kuno A, Ueda HR. Susaki EA, et al. Nat Protoc. 2015 Nov;10(11):1709-27. doi: 10.1038/nprot.2015.085. Epub 2015 Oct 8. Nat Protoc. 2015. PMID: 26448360
Here we describe a protocol for advanced CUBIC (Clear, Unobstructed Brain/Body Imaging Cocktails and Computational analysis). The CUBIC protocol enables simple and efficient organ clearing, rapid imaging by light-sheet microscopy and quantitative imaging analysis of …
Here we describe a protocol for advanced CUBIC (Clear, Unobstructed Brain/Body Imaging Cocktails and Computational analysis). The CUB …
A protocol for combining fluorescent proteins with histological stains for diverse cell wall components.
Ursache R, Andersen TG, Marhavý P, Geldner N. Ursache R, et al. Plant J. 2018 Jan;93(2):399-412. doi: 10.1111/tpj.13784. Plant J. 2018. PMID: 29171896 Free article.
Higher plant function is contingent upon the complex three-dimensional (3D) architecture of plant tissues, yet severe light scattering renders deep, 3D tissue imaging very problematic. Although efforts to 'clear' tissues have been ongoing for over a century, many innovatio …
Higher plant function is contingent upon the complex three-dimensional (3D) architecture of plant tissues, yet severe light scattering rende …
Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice.
Gaikwad S, Puangmalai N, Sonawane M, Montalbano M, Price R, Iyer MS, Ray A, Moreno S, Kayed R. Gaikwad S, et al. Sci Transl Med. 2024 Jul 3;16(754):eadj5958. doi: 10.1126/scitranslmed.adj5958. Epub 2024 Jul 3. Sci Transl Med. 2024. PMID: 38959324
Moreover, a single intranasal dose of TTCM2-ms effectively cleared pathological tau, elevated synaptic proteins, and improved cognitive functions in aged tauopathy mice. ...Our study collectively provides evidence of the effectiveness of nasal tau immunotherapy in targetin …
Moreover, a single intranasal dose of TTCM2-ms effectively cleared pathological tau, elevated synaptic proteins, and improved cogniti …
Is It All Clear if Procalcitonin Clears in Acute Pancreatitis?
Kandasamy S. Kandasamy S. Indian J Crit Care Med. 2020 Mar;24(3):149-150. doi: 10.5005/jp-journals-10071-23388. Indian J Crit Care Med. 2020. PMID: 32435089 Free PMC article.
How to cite this article: Kandasamy S. Is It All Clear if Procalcitonin Clears in Acute Pancreatitis? Indian J Crit Care Med 2020;24(3):149-150....
How to cite this article: Kandasamy S. Is It All Clear if Procalcitonin Clears in Acute Pancreatitis? Indian J Crit Care Med 2 …
Centromeric chromatin clearings demarcate the site of kinetochore formation.
Kixmoeller K, Tarasovetc EV, Mer E, Chang YW, Black BE. Kixmoeller K, et al. Cell. 2025 Mar 6;188(5):1280-1296.e19. doi: 10.1016/j.cell.2024.12.025. Epub 2025 Jan 23. Cell. 2025. PMID: 39855195
Using cryo-ET on human mitotic chromosomes, we reveal a distinctive architecture at the centromere: clustered 20- to 25-nm nucleosome-associated complexes within chromatin clearings that delineate them from surrounding chromatin. Centromere components CENP-C and CENP-N are …
Using cryo-ET on human mitotic chromosomes, we reveal a distinctive architecture at the centromere: clustered 20- to 25-nm nucleosome-associ …
Tissue Clearing Approaches in Atherosclerosis.
Sun T, Li Y, Förstera B, Stanic K, Lu S, Steffens S, Yin C, Ertürk A, Megens RTA, Weber C, Habenicht A, Mohanta SK. Sun T, et al. Methods Mol Biol. 2022;2419:747-763. doi: 10.1007/978-1-0716-1924-7_45. Methods Mol Biol. 2022. PMID: 35237999
Methods to acquire subcellular optical access to the intact tissues surrounding healthy and diseased arteries are urgently needed to achieve these aims. Tissue clearing is a landmark next-generation, three-dimensional (3D) microscopy technique that allows to image large-sc …
Methods to acquire subcellular optical access to the intact tissues surrounding healthy and diseased arteries are urgently needed to achieve …
Imaging the Gut with "CLARITY".
Chandrasekharan B, Neish AS. Chandrasekharan B, et al. J Vis Exp. 2021 Jun 11;(172):10.3791/62143. doi: 10.3791/62143. J Vis Exp. 2021. PMID: 34180888 Free PMC article.
CLARITY (Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging compatible Tissue hYdrogel) has recently evolved as a valuable technique involving acrylamide embedding to delipidate tissue (without sectioning) and to preserve the 3-D tissue structure for immunostaining. …
CLARITY (Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging compatible Tissue hYdrogel) has recently evolved as a valuable tec …
High-Speed Clearing and High-Resolution Staining for Analysis of Various Markers for Neurons and Vessels.
Park JM, Choi SH, Lee ES, Gum SI, Hong S, Kim DS, Han MH, Lee SH, Oh JW. Park JM, et al. Tissue Eng Regen Med. 2024 Oct;21(7):1037-1048. doi: 10.1007/s13770-024-00658-w. Epub 2024 Jul 2. Tissue Eng Regen Med. 2024. PMID: 38955906 Free PMC article.
METHODS: Here, we cleared and immune-stained whole mouse brain tissues using a novel clearing technique termed high-speed clearing and high-resolution staining (HCHS). We observed neural structures within the cleared brains using both a confocal micros …
METHODS: Here, we cleared and immune-stained whole mouse brain tissues using a novel clearing technique termed high-speed c …
568,984 results
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