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ErbB-2 induces bilateral adrenal pheochromocytoma formation in mice.
Lai EW, Rodriguez OC, Aventian M, Cromelin C, Fricke ST, Martiniova L, Lubensky IA, Lisanti MP, Picard KL, Powers JF, Tischler AS, Pacak K, Albanese C. Lai EW, et al. Among authors: cromelin c. Cell Cycle. 2007 Aug 1;6(15):1946-50. doi: 10.4161/cc.6.15.4521. Epub 2007 May 31. Cell Cycle. 2007. PMID: 17671425
ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Casimiro M, Rodriguez O, Pootrakul L, Aventian M, Lushina N, Cromelin C, Ferzli G, Johnson K, Fricke S, Diba F, Kallakury B, Ohanyerenwa C, Chen M, Ostrowski M, Hung MC, Rabbani SA, Datar R, Cote R, Pestell R, Albanese C. Casimiro M, et al. Among authors: cromelin c. Cancer Res. 2007 May 1;67(9):4364-72. doi: 10.1158/0008-5472.CAN-06-1898. Cancer Res. 2007. PMID: 17483350
A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
Rodriguez OC, Lai EW, Vissapragada S, Cromelin C, Avetian M, Salinas P, Ramos H, Kallakury B, Casimiro M, Lisanti MP, Tanowitz HB, Pacak K, Glazer RI, Avantaggiati M, Albanese C. Rodriguez OC, et al. Among authors: cromelin c. Am J Pathol. 2009 Jun;174(6):2051-60. doi: 10.2353/ajpath.2009.080859. Epub 2009 May 14. Am J Pathol. 2009. PMID: 19443706 Free PMC article.